Effect and Mechanism of 808 nm Light Pretreatment of Hypoxic Primary Neurons

This study investigated the effect of low intensity 808 nm light pretreatment of hypoxic primary neurons. Cobalt chloride (CoCl2) has been used to induce hypoxic injury in primary mouse cortical neurons. Low intensity 808 nm light was from light-emitting diode (LED). Cells were randomly divided into 4 groups: normal control group, CoCl2-induced group, CoCl2-induced group with 808 nm light irradiation pretreatment, and normal group with 808 nm light irradiation pretreatment. Effect of low intensity 808 nm light on neuronal morphology has been observed by microscope. MTT colorimetric assay has been used to detect the effect of low intensity 808 nm light on neuronal activity. Adenosine triphosphate (ATP) concentration and cytochrome C oxidase (COX) activity has been detected to study the effect of low intensity 808 nm light on neuronal mitochondria function. The results indicated that low intensity 808 nm light pretreatment alone did not affect cell viability, COX activity, and ATP content of neurons and low intensity 808 nm light pretreatment promoted the cell viability, COX activity, and ATP content of neurons with CoCl2 exposure; however, low intensity 808 nm light pretreatment did not completely recover COX activity and cellular ATP content of primary neurons with CoCl2 exposure to the level of the normal neurons

Dirac-boson stars

In this paper, we construct \textit{Dirac-boson stars} (DBSs) model composed of a scalar field and two Dirac fields. The scalar field and both Dirac fields are in the ground state. We consider the solution families of the DBSs for the synchronized frequency $\tilde{\omega}$ and the nonsynchronized frequency $\tilde{\omega}_D$ cases, respectively. We find several different solutions when the Dirac mass $\tilde{\mu}_D$ and scalar field frequency $\tilde{\omega}_S$ are taken in some particular ranges. In contrast, no similar case has been found in previous studies of multistate boson stars. Moreover, we discuss the characteristics of each type of solution family of the DBSs and present the relationship between the ADM mass $M$ of the DBSs and the synchronized frequency $\tilde{\omega}$ or the nonsynchronized frequency $\tilde{\omega}_D$. Finally, we calculate the binding energy $E_B$ of the DBSs and investigate the relationship of $E_B$ with the synchronized frequency $\tilde{\omega}$ or the nonsynchronized frequency $\tilde{\omega}_D$.Comment: 26 pages, 12 figure

Tidal Love numbers of Axion stars

We investigate the tidal deformability of spherically symmetric axion stars on the stable branches, including the Newtonian and relativistic branches. The results suggest that on the stable branch, the electric Love numbers of axion star are positive, while the magnetic Love numbers are negative. On the Newtonian stable branch, the electric tidal Love numbers are much larger than the magnetic ones, while on the relativistic stable branch, they are slightly larger. Furthermore, the relativistic stable branch has much smaller tidal Love numbers than the Newtonian stable branch, indicating weaker deformability of axion stars on the relativistic stable branch. This could be attributed to the fact that on the relativistic branch, axion stars are more compact, resulting hardly distorted by tidal forces.Comment: 22 pages, 5 figure

Excited Dirac stars with higher azimuthal harmonic index

In this paper, we investigate the properties of the first excited state Dirac stars (DSs) with higher azimuthal harmonic index (specifically, the azimuthal harmonic indexes $m_D$ = $3/2$, $5/2$, $7/2$), as well as the relationship between the ADM mass and angular momentum of Dirac stars with respect to frequency. Moreover, We find that the ergospheres of DSs appear at lower spinor field frequencies, and both the ergospheres and the distribution of the spinor field functions are asymmetric about the equatorial plane. Furthermore, we introduce the ground state scalar field and examine its impact on this system, which is known as the multi-state Dirac-boson stars (DBSs) model. We show various types of solution families for DBSs under both synchronized frequency $\omega$ and nonsynchronized frequencies and find that similar to DSs, the spinor field and the ergospheres of DBSs are also asymmetric about the equatorial plane, but the ergospheres appear at higher spinor field frequencies.Comment: 22 pages, 8 figure

Novel Microfiber Sensor and Its Biosensing Application for Detection of hCG Based on a Singlemode-Tapered Hollow Core-Singlemode Fiber Structure

A novel microfiber sensor is proposed and demonstrated based on a singlemode-tapered hollow core -singlemode (STHS) fiber structure. Experimentally a STHS with taper waist diameter of 26.5 μm has been fabricated and RI sensitivity of 816, 1601.86, and 4775.5 nm/RIU has been achieved with RI ranges from 1.3335 to 1.3395 , from 1.369 to 1.378, and from 1.409 to 1.4175 respectively, which agrees very well with simulated RI sensitivity of 885, 1517, and 4540 nm/RIU at RI ranges from 1.3335 to 1.337, from 1.37 to 1.374, and from 1.41 to 1.414 . The taper waist diameter has impact on both temperature and strain sensitivity of the sensor structure: (1) the smaller the waist diameter, the higher the temperature sensitivity, and experimentally 26.82 pm/°C has been achieved with a taper waist diameter of 21.4 μm; (2) as waist diameter decrease, strain sensitivity increase and 7.62 pm/με has been achieved with a taper diameter of 20.3 μm. The developed sensor was then functionalized for human chorionic gonadotropin (hCG) detection as an example for biosensing application. Experimentally for hCG concentration of 5 mIU/ml, the sensor has 0.5 nm wavelength shift, equivalent to limit of detection (LOD) of 0.6 mIU/ml by defining 3 times of the wavelength variation (0.06 nm) as measurement limit. The biosensor demonstrated relatively good reproducibility and specificity, which has potential for real medical diagnostics and other applications