172 research outputs found
Observation of a ppb mass threshoud enhancement in \psi^\prime\to\pi^+\pi^-J/\psi(J/\psi\to\gamma p\bar{p}) decay
The decay channel
is studied using a sample of events collected
by the BESIII experiment at BEPCII. A strong enhancement at threshold is
observed in the invariant mass spectrum. The enhancement can be fit
with an -wave Breit-Wigner resonance function with a resulting peak mass of
and a
narrow width that is at the 90% confidence level.
These results are consistent with published BESII results. These mass and width
values do not match with those of any known meson resonance.Comment: 5 pages, 3 figures, submitted to Chinese Physics
Graphene Photonics and Optoelectronics
The richness of optical and electronic properties of graphene attracts
enormous interest. Graphene has high mobility and optical transparency, in
addition to flexibility, robustness and environmental stability. So far, the
main focus has been on fundamental physics and electronic devices. However, we
believe its true potential to be in photonics and optoelectronics, where the
combination of its unique optical and electronic properties can be fully
exploited, even in the absence of a bandgap, and the linear dispersion of the
Dirac electrons enables ultra-wide-band tunability. The rise of graphene in
photonics and optoelectronics is shown by several recent results, ranging from
solar cells and light emitting devices, to touch screens, photodetectors and
ultrafast lasers. Here we review the state of the art in this emerging field.Comment: Review Nature Photonics, in pres
Murine Gamma Herpesvirus 68 Hijacks MAVS and IKKĪ² to Abrogate NFĪŗB Activation and Antiviral Cytokine Production
Upon viral infection, mitochondrial antiviral signaling (MAVS) protein serves as a key adaptor to promote cytokine production. We report here that murine gamma herpesvirus 68 (Ī³HV68), a model virus for oncogenic human gamma herpesviruses, subverts cytokine production via the MAVS adaptor. During early infection, Ī³HV68 hijacks MAVS and IKKĪ² to induce the site-specific phosphorylation of RelA, a crucial subunit of the transcriptionally active NFĪŗB dimer, which primes RelA for the proteasome-mediated degradation. As such, Ī³HV68 efficiently abrogated NFĪŗB activation and cytokine gene expression. Conversely, uncoupling RelA degradation from Ī³HV68 infection promoted NFĪŗB activation and elevated cytokine production. Loss of MAVS increased cytokine production and immune cell infiltration in the lungs of Ī³HV68-infected mice. Moreover, exogenous expression of the phosphorylation- and degradation-resistant RelA variant restored Ī³HV68-induced cytokine production. Our findings uncover an intricate strategy whereby signaling via the upstream MAVS adaptor is intercepted by a pathogen to nullify the immediate downstream effector, RelA, of the innate immune pathway
Branching fraction measurements of Ļc0 and Ļc2 to Ļ0Ļ0 and Ī·Ī·
Using a sample of 1.06Ć108 Ļ ā² decays collected by the BESIII detector, Ļc0 and Ļc2 decays into Ļ0Ļ0 and Ī·Ī· are studied. The branching fraction results are Br(Ļc0āĻ 0Ļ0)=(3.23Ā±0.03Ā±0.23Ā±0.14)Ć10 -3, Br(Ļc2āĻ0Ļ0)=(8.8Ā±0.2Ā±0.6Ā±0.4)Ć10 -4, Br(Ļc0āĪ·Ī·)=(3.44Ā±0.10Ā±0. 24Ā±0.2)Ć10 -3, and Br(Ļc2āĪ·Ī·)=(6. 5Ā±0.4Ā±0.5Ā±0.3)Ć10 -4, where the uncertainties are statistical, systematic due to this measurement, and systematic due to the branching fractions of Ļ ā²ā Ī³ĻcJ. The results provide information on the decay mechanism of Ļc states into pseudoscalars. Ā© 2010 The American Physical Society.published_or_final_versio
Measurement of the matrix element for the decay Ī·ā²āĪ·Ļ +Ļ -
The Dalitz plot of Ī·āā²āĪ·Ļā+Ļā- decay is studied using (225.2Ā±2.8)Ć106 J/Ļ events collected with the BESIII detector at the BEPCII eā+eā- collider. With the largest sample of Ī·āā² decays to date, the parameters of the Dalitz plot are determined in a generalized and a linear representation. Also, the branching fraction of J/ĻāĪ³Ī·āā² is determined to be (4.84Ā±0.03Ā±0.24)Ć10ā-3, where the first error is statistical and the second systematic. Ā© 2011 American Physical Society.published_or_final_versio
First observation of the decays ĻcJāĻ0Ļ0Ļ0Ļ0
We present a study of the P-wave spin-triplet charmonium Ļ cJ decays (J=0, 1, 2) into Ļ0Ļ0Ļ0Ļ0. The analysis is based on 106Ć106 Ļāā² decays recorded with the BESIII detector at the BEPCII electron positron collider. The decay into the Ļ0Ļ0Ļ0Ļ0 hadronic final state is observed for the first time. We measure the branching fractions B(Ļ c0āĻ0Ļ0Ļ0Ļ0)=(3.34Ā±0. 06Ā±0.44)Ć10ā-3, B(Ļ c1āĻ0Ļ0Ļ0Ļ0) =(0.57Ā±0.03Ā±0.08)Ć10ā-3, and B(Ļ c2āĻ0Ļ0Ļ0Ļ0)=(1.21Ā±0.05Ā±0.16) Ć10ā-3, where the uncertainties are statistical and systematical, respectively. Ā© 2011 American Physical Society.published_or_final_versio
Higher-order multipole amplitude measurement in Ļ ā²āĪ³Ļ c2
Using 106Ć106 Ļ ā² events collected with the BESIII detector at the BEPCII storage ring, the higher-order multipole amplitudes in the radiative transition Ļ ā²āĪ³Ļ c2āĪ³Ļ +Ļ -/Ī³K +K - are measured. A fit to the Ļ c2 production and decay angular distributions yields M2=0.046Ā±0. 010Ā±0.013 and E3=0.015Ā±0.008Ā±0.018, where the first errors are statistical and the second systematic. Here M2 denotes the normalized magnetic quadrupole amplitude and E3 the normalized electric octupole amplitude. This measurement shows evidence for the existence of the M2 signal with 4.4Ļ statistical significance and is consistent with the charm quark having no anomalous magnetic moment. Ā© 2011 American Physical Society.published_or_final_versio
Study of a00(980)-f0(980) mixing
Using samples of 2.25Ć108 J/Ļ events and 1.06Ć108 Ļ ā² events collected with the BES III detector, we study the f 0(980)āa00(980) and a00(980)āf 0(980) transitions in the processes J/ĻāĻf 0(980) āĻa00(980) and Ļ c1āĻ0a00(980)āĻ0f 0(980), respectively. Evidence for f 0(980)āa00(980) is found with a significance of 3.4Ļ, while in the case of a00(980)āf 0(980) transition, the significance is 1.9Ļ. Measurements and upper limits of both branching ratios and mixing intensities are determined. Ā© 2011 American Physical Society.published_or_final_versio
The Current State of Proteomics in GI Oncology
Proteomics refers to the study of the entire set of proteins in a given cell or tissue. With the extensive development of protein separation, mass spectrometry, and bioinformatics technologies, clinical proteomics has shown its potential as a powerful approach for biomarker discovery, particularly in the area of oncology. More than 130 exploratory studies have defined candidate markers in serum, gastrointestinal (GI) fluids, or cancer tissue. In this article, we introduce the commonly adopted proteomic technologies and describe results of a comprehensive review of studies that have applied these technologies to GI oncology, with a particular emphasis on developments in the last 3Ā years. We discuss reasons why the more than 130 studies to date have had little discernible clinical impact, and we outline steps that may allow proteomics to realize its promise for early detection of disease, monitoring of disease recurrence, and identification of targets for individualized therapy
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