Frontiers of parasitology research in the People's Republic of China : infection, diagnosis, protection and surveillance

ABSTRACT: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public health response. A comprehensive effort, involving the collaboration of 188 scientists (<85% from P.R. China) from 48 different institutions and universities (80% from P.R. China), covers this collection of 29 articles published in Parasites & Vectors. The research mainly stems from a research project entitled 'Surveillance and diagnostic tools for major parasitic diseases in P.R. China' (grant no. 2008ZX10004-011) and highlights the frontiers of research in parasitology. The majority of articles in this thematic series deals with the most important parasitic diseases in P.R. China, emphasizing Schistosoma japonicum, Plasmodium vivax and Clonorchis sinensis plus some parasites of emerging importance such as Angiostrongylus cantonensis. Significant achievements have been made through the collaborative research programme in the following three fields: (i) development of control strategies for the national control programme; (ii) updating the surveillance data of parasitic infections both in human and animals; and (iii) improvement of existing, and development of novel, diagnostic tools to detect parasitic infections. The progress is considerable and warrants broad validation efforts. Combined with the development of improved tools for diagnosis and surveillance, integrated and multi-pronged control strategies now pave the way for elimination of parasitic diseases in P.R. China. Experiences and lessons learned can stimulate control and elimination efforts of parasitic diseases in other parts of the world

Engineering the accurate distortion of an object's temperature-distribution signature

It is up to now a challenge to control the conduction of heat. Here we develop a method to distort the temperature distribution signature of an object at will. As a result, the object accurately exhibits the same temperature distribution signature as another object that is predetermined, but actually does not exist in the system. Our finite element simulations confirm the desired effect for different objects with various geometries and compositions. The underlying mechanism lies in the effects of thermal metamaterials designed by using this method. Our work is of value for applications in thermal engineering.Comment: 11 pages, 4 figure