The cos 2 phi asymmetry of Drell-Yan and J/psi production in unpolarized ppbar scattering

We investigate the cos 2 phi azimuthal asymmetry in Drell--Yan and J/psi production from unpolarized ppbar scattering at GSI-HESR energies. The contribution to this asymmetry arising from the leading-twist Boer-Mulders function h_1^perp(x, k_T^2), which describes a correlation between the transverse momentum and the transverse spin of quarks in an unpolarized hadron, is explicitly evaluated, and predictions for the GSI-HESR kinematic regime are presented. We show that the cos 2 phi asymmetry is quite sizable both on the J/psi peak and in the Drell-Yan continuum region. Therefore these processes may offer an experimentally viable access to the Boer-Mulders function in the early unpolarized stage of GSI experiments.Comment: 5 pages, 3 figures, to be published in Eur. Phys.

Hydrogen Sulfide Protects HUVECs against Hydrogen Peroxide Induced Mitochondrial Dysfunction and Oxidative Stress

10.1371/journal.pone.0053147PLoS ONE82

Guest Molecule-Responsive Functional Calcium Phosphonate Frameworks for Tuned Proton Conductivity

We report the synthesis, structural characterization, and functionality of an open-framework hybrid that combines Ca2+ ions and the rigid polyfunctional ligand 5-(dihydroxyphosphoryl) isophthalic acid (PiPhtA). Ca-PiPhtA-I is obtained by slow crystallization at ambient conditions from acidic (pH≈3) aqueous solutions. It possesses a high water content (both Ca coordinated and in the lattice), and importantly, it exhibits water-filled 1D channels. At 75 °C, Ca-PiPhtA-I is partially dehydrated and exhibits a crystalline diffraction pattern that can be indexed in a monoclinic cell with parameters close to the pristine phase. Rietveld refinement was carried out for the sample heated at 75 °C, Ca-PiPhtA-II, using synchrotron powder X-ray diffraction data.All connectivity modes of the “parent” Ca-PiPhtA-I framework are retained in Ca-PiPhtA-II. Upon Ca-PiPhtA-I exposure to ammonia vapors (28% aqueous NH3) a new derivative is obtained (Ca-PiPhtA-NH3) containing 7 NH3 and 16 H2O molecules according to elemental and thermal analyses. Ca-PiPhtA-NH3 exhibits a complex X-ray diffraction pattern with peaks at 15.3 and 13.0 Å that suggest partial breaking and transformation of the parent pillared structure. Although detailed structural identification of Ca-PiPhtA-NH3 was not possible, due in part to nonequilibrium adsorption conditions and the lack of crystallinity, FT-IR spectra and DTA-TG analysis indicate profound structural changes compared to the pristine Ca-PiPhtA-I. At 98% RH and T = 24 °C, proton conductivity, σ, for Ca PiPhtA-I is 5.7 ×10−4 S·cm−1. It increases to 1.3 × 10−3 S·cm−1 upon activation by preheating the sample at 40 °C for 2 h followed by water equilibration at room temperature under controlled conditions. Ca-PiPhtA-NH3 exhibits the highest proton conductivity, 6.6 × 10−3 S·cm−1, measured at 98% RH and T = 24 °C. Ea for proton transfer in the above-mentioned frameworks range between 0.23 and 0.4 eV, typical of a Grothuss mechanism of proton conduction.Proyecto nacional MAT2010-1517

H2S biosynthesis and catabolism: new insights from molecular studies

Hydrogen sulfide (H2S) has profound biological effects within living organisms and is now increasingly being considered alongside other gaseous signalling molecules, such as nitric oxide (NO) and carbon monoxide (CO). Conventional use of pharmacological and molecular approaches has spawned a rapidly growing research field that has identified H2S as playing a functional role in cell-signalling and post-translational modifications. Recently, a number of laboratories have reported the use of siRNA methodologies and genetic mouse models to mimic the loss of function of genes involved in the biosynthesis and degradation of H2S within tissues. Studies utilising these systems are revealing new insights into the biology of H2S within the cardiovascular system, inflammatory disease, and in cell signalling. In light of this work, the current review will describe recent advances in H2S research made possible by the use of molecular approaches and genetic mouse models with perturbed capacities to generate or detoxify physiological levels of H2S gas within tissue

Submerged membrane bioreactor for vegetable oil wastewater treatment

Chemical Engineering and Technology381101-10

Melamine Functionalized Copolymer for Sequence Specific siRNA Loading and Ligand-Driven Delivery

Triamino triazine, also termed melamine, presents three identical interfaces that are capable of recognizing U/T with three hydrogen bonds. When displayed on a polymeric chain, melamine displaying polymers are capable of condensing structureless U/T tracts into triple-stranded structures, which have been conferred with enhanced tolerance towards nuclease degradation and preserved biological function. In this study, a mixed-block copolymer with alternating display of N-Acetylgalactosamine (GalNAc) and melamine p(GM)_(10) is synthesized via reversible addition-fragmentation chain transfer (RAFT). The polymer has been demonstrated to sequence specifically load the 27-mer dicer substrate siRNA targeting ApoB-100 precursor mRNA that is appended with U stretches. The loaded siRNA can be efficiently processed by recombinant dicer, and readily uptaken by HepG2 cells via receptor mediated endocytosis, eliciting an IC 50 of 5 nM. Further, the copolymer is immunologically tolerant as the result of carbohydrate decoration, and induces minimum cytokine release syndrome. Hence, melamine displaying polymer offers a novel siRNA delivery strategy with enhanced RNAi potency; further, RAFT polymerization has been demonstrated to be a versatile platform for synthesizing tailored delivery system with tissue/disease-specific ligand conjugations