54,889 research outputs found

    Force and Mass Dynamics in Non-Newtonian Suspensions

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    Above a certain solid fraction, dense granular suspensions in water exhibit non-Newtonian behavior, including impact-activated solidification. Although it has been suggested that solidification depends on boundary interactions, quantitative experiments on the boundary forces have not been reported. Using high-speed video, tracer particles, and photoelastic boundaries, we determine the impactor kinematics and the magnitude and timings of impactor-driven events in the body and at the boundaries of cornstarch suspensions. We observe mass shocks in the suspension during impact. The shockfront dynamics are strongly correlated to those of the intruder. However, the total momentum associated with this shock never approaches the initial impactor momentum. We also observe a faster second front, associated with the propagation of pressure to the boundaries of the suspension. The two fronts depend differently on the initial impactor speed, v0v_0, and the suspension packing fraction. The speed of the pressure wave is at least an order of magnitude smaller than (linear) ultrasound speeds obtained for much higher frequencies, pointing to complex amplitude and frequency response of cornstarch suspensions to compressive strains

    Nonequilibrium Phase Transitions of Vortex Matter in Three-Dimensional Layered Superconductors

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    Large-scale simulations on three-dimensional (3D) frustrated anisotropic XY model have been performed to study the nonequilibrium phase transitions of vortex matter in weak random pinning potential in layered superconductors. The first-order phase transition from the moving Bragg glass to the moving smectic is clarified, based on thermodynamic quantities. A washboard noise is observed in the moving Bragg glass in 3D simulations for the first time. It is found that the activation of the vortex loops play the dominant role in the dynamical melting at high drive.Comment: 3 pages,5 figure

    Phonon Squeezed States Generated by Second Order Raman Scattering

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    We study squeezed states of phonons, which allow a reduction in the quantum fluctuations of the atomic displacements to below the zero-point quantum noise level of coherent phonon states. We investigate the generation of squeezed phonon states using a second order Raman scattering process. We calculate the expectation values and fluctuations of both the atomic displacement and the lattice amplitude operators, as well as the effects of the phonon squeezed states on macroscopically measurable quantities, such as changes in the dielectric constant. These results are compared with recent experiments.Comment: 4 pages, REVTE

    Analytical Solution of Electron Spin Decoherence Through Hyperfine Interaction in a Quantum Dot

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    We analytically solve the {\it Non-Markovian} single electron spin dynamics due to hyperfine interaction with surrounding nuclei in a quantum dot. We use the equation-of-motion method assisted with a large field expansion, and find that virtual nuclear spin flip-flops mediated by the electron contribute significantly to a complete decoherence of transverse electron spin correlation function. Our results show that a 90% nuclear polarization can enhance the electron spin T2T_2 time by almost two orders of magnitude. In the long time limit, the electron spin correlation function has a non-exponential 1/t21/t^2 decay in the presence of both polarized and unpolarized nuclei.Comment: 4 pages, 3 figure

    Relativistic description of magnetic moments in nuclei with doubly closed shells plus or minus one nucleon

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    Using the relativistic point-coupling model with density functional PC-PK1, the magnetic moments of the nuclei 207^{207}Pb, 209^{209}Pb, 207^{207}Tl and 209^{209}Bi with a jjjj closed-shell core 208^{208}Pb are studied on the basis of relativistic mean field (RMF) theory. The corresponding time-odd fields, the one-pion exchange currents, and the first- and second-order corrections are taken into account. The present relativistic results reproduce the data well. The relative deviation between theory and experiment for these four nuclei is 6.1% for the relativistic calculations and somewhat smaller than the value of 13.2% found in earlier non-relativistic investigations. It turns out that the π\pi meson is important for the description of magnetic moments, first by means of one-pion exchange currents and second by the residual interaction provided by the π\pi exchange.Comment: 11 pages, 7 figure

    Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway.

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    BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction, the induction pathways and potential roles of specific chemokines in TBEV-mediated neurological disease are poorly understood. METHODS: BALB/c mice were intracerebrally injected with TBEV, followed by evaluation of chemokine and cytokine profiles using protein array analysis. The virus-infected mice were treated with the CC chemokine antagonist Met-RANTES or anti-RANTES mAb to determine the role of RANTES in affecting TBEV-induced neurological disease. The underlying signaling mechanisms were delineated using RANTES promoter luciferase reporter assay, siRNA-mediated knockdown, and pharmacological inhibitors in human brain-derived cell culture models. RESULTS: In a mouse model, pathological features including marked inflammatory cell infiltrates were observed in brain sections, which correlated with a robust up-regulation of RANTES within the brain but not in peripheral tissues and sera. Antagonizing RANTES within CNS extended the survival of mice and reduced accumulation of infiltrating cells in the brain after TBEV infection. Through in vitro studies, we show that virus infection up-regulated RANTES production at both mRNA and protein levels in human brain-derived cell lines and primary progenitor-derived astrocytes. Furthermore, IRF-3 pathway appeared to be essential for TBEV-induced RANTES production. Site mutation of an IRF-3-binding motif abrogated the RANTES promoter activity in virus-infected brain cells. Moreover, IRF-3 was activated upon TBEV infection as evidenced by phosphorylation of TBK1 and IRF-3, while blockade of IRF-3 activation drastically reduced virus-induced RANTES expression. CONCLUSIONS: Our findings together provide insights into the molecular mechanism underlying RANTES production induced by TBEV, highlighting its potential importance in the process of neuroinflammatory responses to TBEV infection
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