Methionine enkephalin: immunomodulator in normal volunteers, cancer and AIDS patients

Clinical studies of the immunological effects of methionine enkephalin in normal volunteers, cancer, and AIDS patients are summarized. The major immunology changes seen were increases in T cell subsets, natural killer activity, as well as mitogen blastogenesis. Clinically, the cancer and ARC patients did not develop infections

LES POPULATIONS DE LYMPHOCYTES HUMAINS

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Isoprinosine (Inosiplex): Immunological and clinical effects in man

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

Enkephalins and endorphins: Activation molecules for the immune system and natural killer activity?

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Enkephalins and endorphins as modifiers of the immune system: Present and future

This paper summarizes the data related to the relations between enkephalins and endorphins and the immune system. It is shown that lymphocytes have surface receptors for endorphins and enkephalins. Furthermore, endorphins and enkephalins can influence several immune functions such as antibody synthesis, lymphocyte proliferation, and natural killer cytotoxicity. It is thus possible that the receptors play a functional role. In view of these observations, several hypotheses are proposed. Endorphins and enkephalins are physiological regulators of the immune response (two-hit opioid peptide lymphocyte receptor hypothesis) and they are humoral mediators between the central nervous system and the immune system. They may play a pathogenic role in a variety of diseases with primary or secondary immunological defects. Finally, enkephalins and endorphins can be considered as immunomodulators and modifiers of the biological response and as such may become a tool in the field of immunotherapy.SCOPUS: re.jinfo:eu-repo/semantics/publishe

Immunoregulatory agents: synthetic compounds, microbial extracts, Chinese herbs, neuropeptides and intravenous immunoglobulins

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Preventing transfusion risks: Benefits of and outlook for autologous transfusion

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

IMMUNOTHERAPIE DU CANCER

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

IMMUNOLOGIE ET CANCER

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

The effects of isoprinosine

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe