Day care study showed no differences in long-term symptoms in children who were and were not infected during COVID-19 outbreaks

Peer Reviewe

IDIM: Put on your Mask! - But why? *Easy as Pie*

This video is about protective masks. Why do we wear them? What are the different masks? What do they protect against and what should we pay attention to when wearing a mask? Have fun watching

IDIM: Masque! Mais pourquoi? - Trop facile!

Cette vidéo traite des masques de protection. Pourquoi les portons-nous? Quels sont les différents masques? Contre quoi protègent-ils et à quoi devons-nous faire attention lorsque nous portons un masque? Amusez-vous à regarder! // This video is about protective masks. Why do we wear them? What are the different masks? What do they protect against and what should we pay attention to when wearing a mask? Have fun watching

The changing clinical presentation of COVID-19 in children during the course of the pandemic.

AIM To investigate the evolution of clinical symptoms of COVID-19 in children throughout the pandemic. METHODS In this national prospective surveillance study, symptoms in children hospitalised with COVID-19 were collected from all paediatric hospitals in Switzerland between March 2020 and March 2023. Data was analysed across four time periods, according to the predominantly circulating SARS-CoV-2 variant: T1 (wild-type), T2 (Alpha), T3 (Delta) and T4 (Omicron), as well as by age group. RESULTS The study included 1323 children. The proportion of children admitted to an intensive care unit remained stable throughout the pandemic. However, the pattern and frequency of clinical manifestations changed over time. Respiratory symptoms were less prevalent during T1 (wild-type), fever during T2 (Alpha) and rash during T4 (Omicron). In contrast, fever and neurological symptoms were more prevalent during T4 (Omicron). Newly described symptoms during T4 (Omicron) included conjunctivitis, laryngotracheitis and seizures. Fever was more prevalent among neonates and infants whereas respiratory symptoms were more common among infants. Gastrointestinal symptoms were more frequent among toddlers, while both toddlers and school-aged children presented with neurological symptoms more often than other age groups. CONCLUSION Continuous surveillance is required to detect changes in manifestations and there by be prepared for the optimal management of complications in children with COVID-19

Physical activity promotion in daycare centres in Germany: study protocol for a cross-sectional survey within the BeweKi study

Introduction In Germany, a total of 92.2% of children between the age of 3 and school entry age attend daycare centres. Therefore, daycare centres are a suitable setting to promote physical activity among children. Yet, there is a lack of knowledge on the promotion of physical activity in daycare centres with regards to different structures and concepts, culture/policies/practices and the characteristics of directors and pedagogical staff of daycare centres in Germany. The aim of this study is to investigate (a) the status quo, as well as (b) the fostering and hindering conditions (barriers and facilitators) of physical activity promotion in daycare centres in Germany.Methods and analysis The cross-sectional study will collect data from November 2022 to February 2023. For the sample, about 5500 daycare centres will be drawn from an address database available through the German Youth Institute (DJI) and invited to the survey. From each daycare centre a director and a pedagogical staff member will be asked to fill in a standardised self-administered questionnaire. The survey explores characteristics of the daycare centre and the implementation of physical activity promotion, for example, the extent and form of physical activity promotion, the use and size of indoor and outdoor area, structural conditions such as personal and financial resources, personal attitudes towards physical activity promotion, demographic characteristics of pedagogical staff, structural daycare centre’s characteristics such as proportion of children from socioeconomic disadvantaged groups. In addition, micro-geographical data on socioeconomic and infrastructural environment of the daycare centres will be included in the data set.Ethics and dissemination The study has been received and approved by the Commissioner for Data Protection of the Robert Koch Institute and by the Ethics Committee of Alice Salomon Hochschule Berlin, University of Applied Sciences. Results will be disseminated through publications and presentations to scientific community and stakeholders

IDIM: Pandemic - easy as pie! *for kids*

In this video, the medical student Juliane Wurm explains everything about a pandemic, why everyone is talking about it and what you can do to help. Have fun watching! // In diesem Video erklärt euch Juliane Wurm, Medizinstudentin, was eine Pandemie eigentlich ist, warum gerade alle darüber reden und was du tun kannst um mitzuhelfen. Viel Spaß damit

SARS-CoV-2 seroconversion in children attending daycare versus adults in Germany between October 2020 and June 2021

Abstract Background: Data on seroconversion rates after SARS-CoV-2 infection in young children (<6 years) is scarce. The present study compares seroconversion rates between young children and adults and identifies associated factors. Methods: The COALA study (“Corona-outbreak-related examinations in daycare centers”) investigated transmission dynamics of SARS-CoV-2 in daycare centers and associated households (10/2020-06/2021). 114 individuals tested positive for SARS-CoV-2 through PCR either prior to the study period by health authorities or in PCR testing during the study period. Two capillary blood samples were obtained within five weeks consecutively and tested for SARS-CoV-2 IgG-antibodies (second sampling depending on positive PCR). Results from 91 participants (38 young children 1–6 years, 53 adults) were included in the analyses. Results: Seroconversion rate in young children is significantly higher than in adults (97.4% versus 66%). High viral load and longer time interval between the probable date of infection and antibody testing are associated with seroconversion. Conclusions: Our findings depict substantial development of specific antibodies in young children after SARS-CoV-2 infection. This may provide temporary protection from re-infection for young children or severe disease for this age group

IDIM: Pandemie – Kinderleicht erklärt *für Kinder*

In this video, the medical student Juliane Wurm explains everything about a pandemic, why everyone is talking about it and what you can do to help. Have fun watching! // In diesem Video erklärt euch Juliane Wurm, Medizinstudentin, was eine Pandemie eigentlich ist, warum gerade alle darüber reden und was du tun kannst um mitzuhelfen. Viel Spaß damit

IDIM: Herdenimmunität - kinderleicht! *für Kinder*

In diesem Video geht es um Herdenimmunität. Ich erkläre euch was Immunität ist und wie man gegen eine Infektionskrankheit immun wird. Außerdem erfahrt ihr wie eine Gesellschaft Herdenimmunität erlangt. Viel Spaß damit! // This video deals with herd immunity. Medical student Juliane Wurm explains what immunity is and how to become immune against an infectious disease. You will also learn how a society achieves herd immunity. Have fun