1 research outputs found
Copper-Catalyzed Ligand-Free Diazidation of Olefins with TMSN<sub>3</sub> in CH<sub>3</sub>CN or in H<sub>2</sub>O
An environmentally
benign, copper-catalyzed diazidation of a broad
range of olefins, including vinylarenes, unactivated alkenes, allene,
and dienes, under mild conditions with TMSN<sub>3</sub> (trimethylazidosilane)
as azido source, has been developed. This reaction can be carried
out in organic solvent or in aqueous solution where water is the sole
solvent. The functional group compatibility of this reaction is good,
which is proved by late-stage functionalizations of complex substrates