2-[(Diphenyl­phosphor­yl)(hy­droxy)meth­yl]-5-meth­oxy­phenol

In the title compound, C20H19O4P, the dihedral angle between the phenyl rings is 73.3 (4)° and the dihedral angles between the benzene ring and the two phenyl rings are 43.0 (3) and 54.3 (1)°. In the crystal, O—H⋯O hydrogen bonds and weak O—H⋯O inter­actions are observed, which form a supra­molecular sheet parallel to (010)

Poly[bis­(2,2′-bipyridine-κ2 N,N′)deca-μ-oxido-dioxidodicopper(II)tetra­vanadium(V)]

The title compound, [Cu2V4O12(C10H8N2)2]n, shows a two-dimensional copper–vanadate layer composed of eight-membered rings, each containing four corner-sharing VO4 tetra­hedra; these are linked through six penta­coordinated CuII atoms with the 2,2′-bipyridine ligands attached and pointing above and below the plane of the layer. The Cu atom is coordinated by two N donors from the 2,2′-bipyridine ligand and three O atoms from three adjacent VO4 units to form a distorted tetragonal pyramid. These layers are further connected by π–π inter­actions between inter­leaving bipyridine ligands of adjacent layers [centroid–centroid distances = 3.63 (1) and 3.68 (1) Å] into a three-dimensional supra­molecular structure

Poly[[diaqua-μ2-4,4′-bipyridyl-μ2-o-phthalato-nickel(II)] dihydrate]

In the title layer complex, {[Ni(C8H4O4)(C10H8N2)(H2O)2]·2H2O}n, the Ni atom has a distorted octa­hedral environment, defined by the phthalate and 4,4′-bipyridyl ligands which link the Ni atoms, forming a square lattice in the bc plane. This extends into a three-dimensional supra­molecular network through O—H⋯O hydrogen-bonding inter­actions. The Ni atom lies on, and both ligands are bis­ected by, a crystallographic twofold axis

Bioactive selaginellins from Selaginella tamariscina (Beauv.) Spring

A new selaginellin named selaginellin O (1), along with three other known selaginellins (2–4) were isolated from Selaginella tamariscina (Beauv.) Spring. On the basis of spectroscopic analysis, the structure of selaginellin O was demonstrated to be 4-[(4’-hydroxy-4-formyl-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one. Compound 1, 2 and 3 exhibited appreciable cytotoxic activity against cultured HeLa cells (human cervical carcinoma cells), as well as significant antioxidant activity

A new phenylethyl alkyl amide from the Ambrostoma quadriimpressum Motschulsky

A new phenylethyl alkyl amide, (10R)-10-hydroxy-N-phenethyloctadecanamide (1), was isolated from the beetle Ambrostoma quadriimpressum Motschulsky. The structure of the amide was determined by NMR and MS. The absolute configuration of compound 1 was confirmed by an asymmetric total synthesis, which was started from L-glutamic acid. The construction of the aliphatic chain was accomplished by the selective protection of the hydroxy groups and two-time implementation of the Wittig olefination reaction

Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines

The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type ring opening followed by cyclization of the resulting haloalkoxy amine

Visible-light photoredox catalysis enabled bromination of phenols and alkenes

A mild and efficient methodology for the bromination of phenols and alkenes has been developed utilizing visible light-induced photoredox catalysis. The bromine was generated in situ from the oxidation of Br− by Ru(bpy)33+, both of which resulted from the oxidative quenching process

Visible-light-induced bromoetherification of alkenols for the synthesis of β-bromotetrahydrofurans and -tetrahydropyrans

A visible-light-induced photoredox-catalyzed bromoetherification of alkenols is described. This approach, with CBr4 as the bromine source through generation of bromine in situ, provides a mild and operationally simple access to the synthesis of β-bromotetrahydrofurans and -tetrahydropyrans with high efficiency and regioselectivity

Visible-Light-Promoted Direct Amination of Phenols via Oxidative Cross-Dehydrogenative Coupling Reaction

A transition-metal-free approach was disclosed for intermolecular aryl C–N bonds formation between phenols and cyclic anilines via cross-dehydrogenative coupling (CDC) amination that was mediated by visible light, wherein K₂S₂O₈ served as an external oxidant. The salient features of this protocol include circumventing the requirement for prefunctionalized starting materials and achieving single regioselectivity of amination adducts at room temperature