Short-Term Analysis of Human Dental Pulps After Direct Capping with Portland Cement

This study evaluated the short-term response of human pulp tissue when directly capped with Portland cement. In this series of cases, twenty human third molars that were scheduled for extraction were used. After cavity preparation, pulp exposure was achieved and Portland cement pulp capping was performed. Teeth were extracted after 1, 7, 14 and 21 days following treatment and prepared for histological examination and bacterial detection. Each group had 5 teeth. The results were descriptively analysed. Dentin bridge formation was seen in two teeth with some distance from the material interface (14 and 21 days). Soft inflammatory responses were observed in most of the cases. Bacteria were not disclosed in any specimen. PC exhibited some features of biocompatibility and capability of inducing mineral pulp response in short-term evaluation. The results suggested that PC has a potential to be used as a less expensive pulp capping material in comparison to other pulp capping materials

Predicting Important Residues and Interaction Pathways in Proteins Using Gaussian Network Model: Binding and Stability of HLA Proteins

A statistical thermodynamics approach is proposed to determine structurally and functionally important residues in native proteins that are involved in energy exchange with a ligand and other residues along an interaction pathway. The structure-function relationships, ligand binding and allosteric activities of ten structures of HLA Class I proteins of the immune system are studied by the Gaussian Network Model. Five of these models are associated with inflammatory rheumatic disease and the remaining five are properly functioning. In the Gaussian Network Model, the protein structures are modeled as an elastic network where the inter-residue interactions are harmonic. Important residues and the interaction pathways in the proteins are identified by focusing on the largest eigenvalue of the residue interaction matrix. Predicted important residues match those known from previous experimental and clinical work. Graph perturbation is used to determine the response of the important residues along the interaction pathway. Differences in response patterns of the two sets of proteins are identified and their relations to disease are discussed

Internationales Treffen der Strömungsforscher im DLR Göttingen

Strömungsforscher und Messtechnikentwickler aus der ganzen Welt treffen sich vom 23. bis 25. September 2009 im Deutschen Zentrum für Luft- und Raumfahrt Göttingen (DLR). Im Mittelpunkt der Konferenz steht die heutzutage wichtigste Messtechnik zur Messung von Strömungsgeschwindigkeiten, die sogenannte Particle Image Velocimetry (PIV). Forscher der Universität Oldenburg hatten sie vor 25 Jahren zusammen mit Kollegen aus dem DLR erstmals in einem Windkanal in Göttingen erprobt

Das Eichsfeld aus der Satellitenperspektive

Auf aktuellem Forschungsstand wird das Eichsfeld in dieser Publikation einer umfassenden landeskundlichen Betrachtung unterzogen. Die unterschiedlichen Sichtweisen aller relevanten natur- und geisteswissenschaftlichen Disziplinen kommen dabei zum Tragen