5,084 research outputs found

    An architecture of internet based data processing based on multicast and anycast protocols

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    Most of the current web-based application systems suffer from poor performance and costly heterogeneous accessing. Distributed or replicated strategies can alleviate the problem in some degree, but there are still some problems of the distributed or replicated model, such as data synchronization, load balance, and so on.&nbsp; In this paper, we propose a novel architecture for Internet-based data processing system based on multicast and anycast protocols. The proposed architecture breaks the functionalities of existing data processing system, in particular, the database functionality, into several agents. These agents communicate with each other using multicast and anycast mechanisms. We show that the proposed architecture provides better scalability, robustness, automatic load balance, and performance than the current distributed architecture of Internet-based dataprocessing.<br /

    BIOMECHANICAL EFFECT OF GROUP EXERCISE PROGRAM USING STABILITY BALL ON THE COUNTER MOVEMENT JUMP

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    The purpose of this study was to evaluate the training effect of three-month group exercise program using stability ball. Ten female subjects were recruited to join this group exercise class for three months. The biomechanical parameters of counter-movement jump were collected before and after class. The average of maximal jumping height and the take-off velocity have significantly increased after three months. The group exercise program accoring American College of Sport Medicine trainig guideline which was designed in this study was helpful to increase the jump height of counter movement jump and to improve the biomechanical parameters of the landing

    Landau-Zener-Stuckelberg-Majorana interference in a 3D transmon driven by a chirped microwave

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    By driving a 3D transmon with microwave fields, we generate an effective avoided energy-level crossing. Then we chirp microwave frequency, which is equivalent to driving the system through the avoided energy-level crossing by sweeping the avoided crossing. A double-passage chirp produces Landau-Zener-St\"uckelberg-Majorana interference that agree well with the numerical results. Our method is fully applicable to other quantum systems that contain no intrinsic avoided level crossing, providing an alternative approach for quantum control and quantum simulation

    Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.

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    Type IIA topoisomerases (Top2s) manipulate the handedness of DNA crossovers by introducing a transient and protein-linked double-strand break in one DNA duplex, termed the DNA-gate, whose opening allows another DNA segment to be transported through to change the DNA topology. Despite the central importance of this gate-opening event to Top2 function, the DNA-gate in all reported structures of Top2-DNA complexes is in the closed state. Here we present the crystal structure of a human Top2 DNA-gate in an open conformation, which not only reveals structural characteristics of its DNA-conducting path, but also uncovers unexpected yet functionally significant conformational changes associated with gate-opening. This structure further implicates Top2's preference for a left-handed DNA braid and allows the construction of a model representing the initial entry of another DNA duplex into the DNA-gate. Steered molecular dynamics calculations suggests the Top2-catalyzed DNA passage may be achieved by a rocker-switch-type movement of the DNA-gate
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