10,776 research outputs found

    On p_T-broadening of high energy partons associated with the LPM effect in a finite-volume QCD medium

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    We study the contributions from radiation to pp_{\perp}-broadening of a high energy parton traversing a QCD medium with a finite length LL. The interaction between the parton and the medium is described by decorrelated static multiple scattering. Amplitudes of medium-induced gluon emission and parton self-energy diagrams are evaluated in the soft gluon limit in the BDMPS formalism. We find both the double-logarithmic correction from incoherent scattering, which is parametrically the same as that in single scattering, and the logarithmic correction from the LPM effect. Therefore, we expect a parametrically large correction from radiation to the medium-induced pp_\perp-broadening in perturbative QCD.Comment: 19 pages, focusing only on calculations about the medium-induced diagrams, origin for double-log reinterpreted, final version to appear in JHE

    Unsupervised visual domain adaptation via dictionary evolution

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    © 2016 IEEE. In real-word visual applications, distribution mismatch between samples from different domains may significantly degrade classification performance. To improve the generalization capability of classifier across domains, domain adaptation has attracted a lot of interest in computer vision. This work focuses on unsupervised domain adaptation which is still challenging because no labels are available in the target domain. Most of the attention has been dedicated to seeking domain-invariant feature by exploring the shared structure between domains, ignoring the valuable discriminative information contained in the labeled source data. In this paper, we propose a Dictionary Evolution (DE) approach to construct discriminative features robust to domain shift. Specifically, DE aims to adapt a discriminative dictionary learnt based on labeled source samples to unlabeled target samples through a gradual transition process. We show that the learnt dictionary is endowed with cross-domain data representation ability and powerful discriminant capability. Empirical results on real world data sets demonstrate the advantages of the proposed approach over competing methods

    Magnetic field mediated low-temperature resistivity upturn in electron-doped La1-xHfxMnO3 manganite oxides

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    Phase diagram and spin-glass phenomena in electron-doped La1-xHfxMnO3 (0.05 ≤ x ≤ 0.3) manganite oxides

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    The effects of tetravalent hafnium doping on the structural, transport, and magnetic properties of polycrystalline La1−xHfxMnO3 (LHMO) (0.05 ≤ x ≤ 0.3) were investigated systematically. LHMO exhibited a typical colossal magnetoresistance effect via the double-exchange between Mn2+ and Mn3+ ions, instead of that between Mn3+ and Mn4+ ions in hole-doped manganites. A phase diagram was obtained for the first time through magnetization and resistance measurements in a broad temperature range. As the Hf concentration varied from x = 0.05 to 0.3, the Curie point and metal-to-insulator transition temperature increased significantly, whereas the magnetization and resistivity decreased remarkably. An abnormal enhancement of the magnetization was observed at about 42 K. It was further confirmed that a second magnetic phase MnO2 in LHMO gives rise to such a phenomenon. The possible causes are discussed in detail. The dynamic magnetic properties of LHMO, including relaxation and aging processes, were studied, demonstrating a spin-glass state at low temperature accompanied by a ferromagnetic phase.published_or_final_versio

    Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission

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    BACKGROUND: Dendritic cell (DC) transmission of human immunodeficiency virus (HIV) to CD4+ T cells occurs across a point of cell-cell contact referred to as the infectious synapse. The relationship between the infectious synapse and the classically defined immunological synapse is not currently understood. We have recently demonstrated that human B cells expressing exogenous DC-SIGN, DC-specific intercellular adhesion molecule-3 (ICAM-3)-grabbing nonintegrin, efficiently transmit captured HIV type 1 (HIV-1) to CD4+ T cells. K562, another human cell line of hematopoietic origin that has been extensively used in functional analyses of DC-SIGN and related molecules, lacks the principal molecules involved in the formation of immunological synaptic junctions, namely major histocompatibility complex (MHC) class II molecules and leukocyte function-associated antigen-1 (LFA-1). We thus examined whether K562 erythroleukemic cells could recapitulate efficient DC-SIGN-mediated HIV-1 transmission (DMHT). RESULTS: Here we demonstrate that DMHT requires cell-cell contact. Despite similar expression of functional DC-SIGN, K562/DC-SIGN cells were inefficient in the transmission of HIV-1 to CD4+ T cells when compared with Raji/DC-SIGN cells. Expression of MHC class II molecules or LFA-1 on K562/DC-SIGN cells was insufficient to rescue HIV-1 transmission efficiency. Strikingly, we observed that co-culture of K562 cells with Raji/DC-SIGN cells impaired DMHT to CD4+ T cells. The K562 cell inhibition of transmission was not directly exerted on the CD4+ T cell targets and required contact between K562 and Raji/DC-SIGN cells. CONCLUSIONS: DMHT is cell type dependent and requires cell-cell contact. We also find that the cellular milieu can negatively regulate DC-SIGN transmission of HIV-1 in trans

    Evaluation of Negation and Uncertainty Detection and its Impact on Precision and Recall in Search

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    Radiology reports contain information that can be mined using a search engine for teaching, research, and quality assurance purposes. Current search engines look for exact matches to the search term, but they do not differentiate between reports in which the search term appears in a positive context (i.e., being present) from those in which the search term appears in the context of negation and uncertainty. We describe RadReportMiner, a context-aware search engine, and compare its retrieval performance with a generic search engine, Google Desktop. We created a corpus of 464 radiology reports which described at least one of five findings (appendicitis, hydronephrosis, fracture, optic neuritis, and pneumonia). Each report was classified by a radiologist as positive (finding described to be present) or negative (finding described to be absent or uncertain). The same reports were then classified by RadReportMiner and Google Desktop. RadReportMiner achieved a higher precision (81%), compared with Google Desktop (27%; p < 0.0001). RadReportMiner had a lower recall (72%) compared with Google Desktop (87%; p = 0.006). We conclude that adding negation and uncertainty identification to a word-based radiology report search engine improves the precision of search results over a search engine that does not take this information into account. Our approach may be useful to adopt into current report retrieval systems to help radiologists to more accurately search for radiology reports

    Preferential regulation of stably expressed genes in the human genome suggests a widespread expression buffering role of microRNAs

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    In this study, we comprehensively explored the stably expressed genes (SE genes) and fluctuant genes (FL genes) in the human genome by a meta-analysis of large scale microarray data. We found that these genes have distinct function distributions. miRNA targets are shown to be significantly enriched in SE genes by using propensity analysis of miRNA regulation, supporting the hypothesis that miRNAs can buffer whole genome expression fluctuation. The expression-buffering effect of miRNA is independent of the target site number within the 3'-untranslated region. In addition, we found that gene expression fluctuation is positively correlated with the number of transcription factor binding sites in the promoter region, which suggests that coordination between transcription factors and miRNAs leads to balanced responses to external perturbations
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