43 research outputs found
A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol
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Influence of chronic phenytoin administration on the pharmacokinetics and pharmacodynamics of vecuronium
No full textInfluence of renal failure on the pharmacokinetics and neuromuscular effects of a single dose of rapacuronium bromide
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A pharmacokinetic-dynamic explanation of the rapid onset-offset of rapacuronium
No full textThe rapid onset and offset of rapacuronium can be explained from its pharmacokinetic and pharmacodynamic characteristics. A unique property of rapacuronium is its high value for k(e0), indicating a rapid access to the receptor site. The reason for this high k(e0) may be related to the low intrinsic potency of rapacuronium, but this is not yet fully clarified
