\u27A slap in the face\u27: Morehead laments plan to cut funds - for Kentucky Folk Art Center

https://scholarworks.moreheadstate.edu/college_histories/1163/thumbnail.jp

Accelerating waters: an Anthropocene history of Colorado's 1976 Big Thompson Flood

2016 Summer.Includes bibliographical references.Scale matters. But in the Anthropocene, it is not clear how environmental scholars navigate between analytical levels from local and regional phenomena on the one hand, to global Earth-system processes on the other. The Anthropocene, in particular, challenges the ways in which history has traditionally been conceived and narrated, as this new geological epoch suggests that humans now rival the great forces of nature. The Big Thompson River Flood of 1976 provides an opportunity to explore these issues. Over the Anthropocene's "Great Acceleration" spike, human activities and environmental change intensified both in Colorado's Big Thompson Canyon and across much of the world. The same forces that amplified human vulnerability to the catastrophic deluge on a micro-level through highway construction, automobile vacationing, and suburban development were also at work with the planetary upsurge in roads, cars, tourism, atmospheric carbon dioxide, and flooding on the macro-level. As a theoretical tool, the Anthropocene offers a more ecological means to think and write about relationships among time and space

Nitric oxide-dependent vasodilation is compromised in isolated pulmonary arteries from COX knockout mice

Cyclooxygenase (COX) has two isoforms and is essential for prostanoid synthesis. COX-1 is constitutive whilst COX-2 is induced in inflammation. Two COX products, prostacyclin (PGI2) and thromboxane (TxA2), regulate vessel tone; PGI2 mediates vasodilation and platelet inhibition, and TxA2 opposes this. PGI2 therapies are used in pulmonary arterial hypertension (PAH). Endogenous TxA2/PGI2 has been linked to PAH in animal models, but the mechanism and isoform involved is debated. We hypothesized that pulmonary artery (PA) from COX-1–/– and COX-2–/– mice would have altered vasodilatory function compared with wild-type (WT; C57Bl6) mice. Vasomotor responses to contractile and relaxant agents were measured by myography. PA from all mice responded similarly to contraction by high potassium or the TxA2 mimetic, U46619. Relaxation to PGI2 receptor or PPARβ/ agonists was also similar in all PAs. However, COX-1–/– and, to a lesser extent, COX-2–/– PA had impaired vasodilation to acetylcholine (ACh), which stimulates endothelial nitric oxide (NO) release, and COX-1–/– PA also dilated less to sodium nitroprusside (SNP); an NO donor that works on smooth muscle (Fig 1). These data indicate an interaction between COX and NO sensing pathways in pulmonary vessels, and have implications for our understanding of PAH.Non peer reviewedFinal Accepted Versio

In Kentucky, Ivanka Trump touts \u27booming\u27 economy

Article published in the Lexington Herald Leader on October 27, 2018 by Will Wright. Discusses Ivanka Trump\u27s visit to Morehead State with Governor Bevin.https://scholarworks.moreheadstate.edu/college_histories/1264/thumbnail.jp

Living with the tsunami: Contested knowledges, spatial politics and everyday practices in South East Sri Lanka

The thesis offers an ethnographic account of the ongoing legacies of the 2004 Indian Ocean tsunami, focusing explicitly on communities in Arugam Bay, South East Sri Lanka. It provides empirical evidence that the tsunami should not be considered ‘over’ or an ‘event’ confined to the past, but instead that it is ongoing, shaping everyday life. The thesis argues that ongoing experiences of the tsunami are not equal, and it unpicks some of the relationships that shape these inequalities, specifically with regards to knowledge production in relation to the disaster. In doing this, it highlights the contested geographies surrounding the area. The thesis presents three overlapping ways in which the tsunami continues to be experienced in everyday life: through its spectacularisation and commodification; through the practices of (I)NGOs; and through the lived coastscape. Informed by literature that seeks to understand disasters and places ‘on their own terms’, the thesis develops the concept of ‘communities of practice’: a theory of practice which highlights the contextual nature of practices in everyday life, emphasising that they are both influenced by discursive and embodied knowledges, and in turn, produce knowledges. This term is used heuristically to explore the tsunami’s legacies, and highlights the ways in which specific knowledges are produced and contested in the area. The thesis focuses specifically on four key communities of practice: fishing; tourism; surfing; and researching. These are central to the production of everyday life and hence embodied knowledges of the tsunami, and are therefore present throughout the whole thesis. Running alongside this are a number of themes: the agency of the more-than-human, specifically the sea; memory and memorialisation of disaster; and broader theories of space and place. These are mobilised to argue that people continue to live with the tsunami as a part of everyday life