Uji Efek Pemberian Ekstrak Biji Petai Cina (Leucaena Leucochepala L) Terhadap Kadar Gula Darah Tikus Wistar (Rattus Norvegicus) Yang Diinduksi Dengan Aloksan

: Public believes that Lead Tree seeds (Leucaena leucochepala L) as a kind of medicinal plant that have capability of treating a lot of diseases, among them is diabetes. This study aimed to test whether the Lead tree seeds extract can reduce blood glucose levels of Wistar rats (R. norvegicus) which has induced alloxan. The subjects in these research were male wistar rat with total of 18 samples divided into six groups consisting of a negative control group and five groups induced by alloxan with dose 130 mg/kgBW of rat, which can cause wistar rats in hyperglycemic state. Hyperglycemic rats were given lead tree seed extract at a dose of 0,14 mg/200 gBW, 0,3 mg/200 gBW, and 0,6 mg/200 gBW, positive control group was given insulin analogue, and one group was given alloxan. Data obtained from the examination of blood glucose levels in all groups of Wistar rats on day zero, day one and day two every six hours on 0, 6, 12, 18, and 24. The results showed that giving lead tree seed extract does not have the effect to reduce blood glucose levels Wistar rats

Uji Efek Ekstrak Umbi Bawang Putih (Allium Sativum L.) Terhadap Kadar Glukosa Darah Tikus Wistar (Rattus Norvegicus) Yang Diinduksi Aloksan

: Garlic (A. sativumL.) is one of many herbal medicine that have been used worldwide to prevent and treat a lot of disease, for example to treat diabetes mellitus. This research aimed to evaluate the effect of garlic bulbs extract administration on elevated blood glucose levels on Wistar rats (R. norvegicus) induced by alloxan. The subjects inthis research were male Wistar rats with total of 18 samples divided into six groups as follows negative control group and five hyperglycemic groups induced by 130 mg/kgBW of alloxan. Garlic bulbs extract was administered with dose of 3 mg/200 gBW of rat, 6 mg/200 gBW of rats, and 12 mg/200 gBW on each groups of hyperglycemic rats, insulin analogue was administered on positive control groups of hyperglycemic rats, and only alloxan was given to the last group. Blood glucose levels was measured on day zero, day one and day two every six hours on 0, 6, 12, 18, and 24. Data from the measurement showed that 6 mg/200 gBW and 12 mg/200 gBW of garlic bulbs extract can reduce elevated blood glucose levels on Wistar rats. Garlic bulbs extract has shown effect on reducing elevated blood glucose levels on Wistar rats induced by alloxan

Uji Efek Ekstrak Buah Okra (Abelmoschus Esculentus) Terhadap Kadar Glukosa Darah Pada Tikus Wistar (Rattus Norvegicus) Yang Diinduksi Aloksan

: Okra (Abelmoschus esculentus) is one of many herbal medicine that have been used worldwide to prevent and treat diabetes mellitus. This research aimed to evaluate the effect of garlic bulbs extract administration on elevated blood glucose levels on Wistar rats (R. norvegicus) induced by alloxan. The subject in this research were male Wistar rats with total of 15 samples divided into 5 groups, consisting of one negative control group, one positive control group who were induce by 130 mg/kgBW of alloxan that cause the Rats in conditions of hyperglycemic, and three groups of Rats were given okra extract with dose of 0.375 ml/100 gBW of rat, 0.75 ml/100 gBW of rat , and 1.5 ml/100 gBW of rat. Blood glucose levels was measured on day zero, day one and day two every thirty minutes on 0, 30, 60, 90, 120, and every six hours on 0, 6, 12, 18, and 24. Data from the measurement showed that 0.375 ml/100 gBW, 0.75 ml/100 gBW , and 1.5 ml/100 gBW of okra extract can't reduce elevated blood glucose levels on Wistar rats