Time and Geometric Quantization

In this paper we briefly review the functional version of the Koopman-von Neumann operatorial approach to classical mechanics. We then show that its quantization can be achieved by freezing to zero two Grassmannian partners of time. This method of quantization presents many similarities with the one known as Geometric Quantization.Comment: Talk given by EG at "Spacetime and Fundamental Interactions: Quantum Aspects. A conference to honour A.P.Balachandran's 65th birthday

Myelomeningocele: neglected aspects

The commonest cause of neurogenic bladder in children is myelomeningocele. Survival of children is much improved in the Western world, but by 35 years old, about 50% will have died. In adults, the commonest causes of death are lung and heart diseases. All physical aspects deteriorate with age, especially in those with thoracic lesions. Those who walk in childhood have a 20–50% chance of becoming wheelchair dependent as adults. Immobility, poor respiratory reserve, obesity, latex allergy and worsening kyphoscoliosis contribute to the increased risks of surgery. It is essential that safe and manageable urine drainage is established in childhood: the bladder never improves with time, and surgical reconstruction becomes progressively more difficult. Independence in adult life will only be possible with intense preparation in childhood. Children must be allowed to join in with family chores and events. Education, both academic and practical, must be encouraged. Skills such as driving, shopping and birth control must be taught. However, even with the best support, less than 40% will have gainful employment. Children who are continent and have lesions below L2 are likely to have normal sexual function. Sexual activity in adolescents, especially in those with hydrocephalus, is limited (but not absent). However, by adult life, about two thirds will have established a regular partnership. All females and those males who are naturally potent are likely to be fertile. There is a high risk of neural tube defects in their offspring unless the female partner takes prophylactic folic acid for 3 months before pregnancy and for first trimester

Refinement of the n−αn-\alpha and p−αp-\alpha fish-bone potential

The fishbone potential of composite particles simulates the Pauli effect by nonlocal terms. We determine the $n-\alpha$ and $p-\alpha$ fish-bone potential by simultaneously fitting to the experimental phase shifts. We found that with a double Gaussian parametrization of the local potential can describe the $n-\alpha$ and $p-\alpha$ phase shifts for all partial waves.Comment: 3 pages, 3 figure

Evaluating the multiple benefits of a sustainable drainage scheme in Newcastle, UK

Sustainable Drainage Systems (SuDS) and Blue-Green infrastructure (BGI) provide a range of environmental, economic and social benefits in addition to managing water quantity and quality. Recognition of the multifunctionality of SuDS and BGI, and the specific benefits that may accrue to different beneficiaries, may facilitate partnership working towards multifunctional infrastructure that meets the strategic objectives of public and private organisations. We evaluate the multiple benefits of the Killingworth and Longbenton surface water management scheme, a Partnership Project in NE England jointly funded by Northumbrian Water, the Environment Agency and North Tyneside Council. Using CIRIA’s Benefits of SuDS Tool (BeST) and the Blue-Green Cities Multiple Benefits GIS Toolbox, we a) quantify and monetise six key benefits, b) assess two qualitative benefits, c) illustrate the spatial distribution of five non-flood benefits, and d) highlight locations with the greatest opportunity for multi-beneficial intervention. The Killingworth and Longbenton scheme generates; significant flood damage reduction benefits; improves water quality, habitat size, carbon sequestration, attractiveness of the area and property prices (amenity), and; reduces noise pollution. Utilisation of these complementary tools for multiple benefit evaluation shows promise as an aid to facilitate partnership working towards implementation of multifunctional SuDS and BGI

Pharmaceutical transition to non-CFC pressurized metered dose inhalers

The production of ozone-depleting chlorofluorocarbons (CFCs) was discontinued on 1 January 1996 for all uses deemed non-essential under the Montreal Protocol. However, the use of CFCs as propellants in pressurized metered dose inhalers (pMDIs) was classed as essential, providing an exemption from the agreement. Following extensive research, the hydrofluoroalkanes (HFA) 134a and 227 were identified as the only suitable replacements for CFC propellants in pMDIs.The drug delivery of pMDIs formulated with HFA 134a as a propellant and containing either salbutamol (100 μg per actuation) or fluticasone propionate (125 and 250 μg per actuation) have been assessed for dose uniformity and particle size distribution.All of the HFA 134a pMDIs delivered doses throughout the life of the canisters that were reproducible and within specified regulatory requirements. Each of the products provided an emitted dose which was within ±25% of the mean value indicating accurate and consistent dosing (93, 112 and 221 μg per metered dose for the salbutamol 100 μg and fluticasone propionate 125 and 250 μg HFA 134a pMDIs, respectively). These findings were unaffected by changing the storage orientation of the pMDI or by using the device in a manner designed to simulate typical patient use. The particle size distributions of HFA 134a pMDI doses did not differ significantly from those of the corresponding CFC pMDIs. As a result of the similar pharmaceutical performance, it is unnecessary to change the label claim dose of active drug when making the transition from a CFC to an HFA 134a pMDI for salbutamol (VentolinTM) and fluticasone propionate (FlixtideTM). A seamless transition to non-CFC pMDIs will help to maintain the confidence of patients and healthcare professionals in asthma therapy

Conformal Spinning Quantum Particles in Complex Minkowski Space as Constrained Nonlinear Sigma Models in U(2,2) and Born's Reciprocity

We revise the use of 8-dimensional conformal, complex (Cartan) domains as a base for the construction of conformally invariant quantum (field) theory, either as phase or configuration spaces. We follow a gauge-invariant Lagrangian approach (of nonlinear sigma-model type) and use a generalized Dirac method for the quantization of constrained systems, which resembles in some aspects the standard approach to quantizing coadjoint orbits of a group G. Physical wave functions, Haar measures, orthonormal basis and reproducing (Bergman) kernels are explicitly calculated in and holomorphic picture in these Cartan domains for both scalar and spinning quantum particles. Similarities and differences with other results in the literature are also discussed and an extension of Schwinger's Master Theorem is commented in connection with closure relations. An adaptation of the Born's Reciprocity Principle (BRP) to the conformal relativity, the replacement of space-time by the 8-dimensional conformal domain at short distances and the existence of a maximal acceleration are also put forward.Comment: 33 pages, no figures, LaTe

Individual Differences in Notetaking, Summarization, and Learning from Lectures

This study investigated working memory, verbal ability, and prior knowledge as predictors of the quality of: (a) students' notes taken during a lecture; (b) summaries of the lecture written during a review period; and (c) recall of the lecture content. The usefulness of taking notes was considered in terms of quality of summarization and recall of the lecture material for three groups of students who: (a) listened to the lecture, took notes, and reviewed those notes; (b) listened to the lecture and reviewed a set of provided notes; or (c) listened to the lecture, took notes, and then reviewed a set of provided notes. Results indicated that students with higher working memory benefit more from listening to the lecture than listening and taking notes. However, the quality of summaries written was a more powerful predictor of performance than the individual differences students' brought to the task. This study extends previous studies by integrating summarization and lecture learning research and providing new insight into the role of notetaking and its relationship to working memory.La mémoire de travail, l'habileté verbale et les connaissances préalables ont été étudiées pour leur valeur prédictive de la qualité: (a) des notes que prenaient les étudiants pendant le cours; (b) des résumés de cours rédigés pendant une période de révision; et (c) du rappel du contenu de cours. L'utilité de la prise de notes a été évaluée d'après la qualité des résumés et le rappel du contenu de cours chez trois groupes d'étudiants qui: (a) écoutaient le cours, prenaient des notes et les révisaient; (b) écoutaient le cours et révisaient des notes qu 'on leur fournissait; ou (c) écoutaient le cours, prenaient des notes et révisaient ensuite des notes qu'on leur fournissait. Les résultats indiquent que, pour les étudiants qui ont une plus grande mémoire de travail, il est plus profitable de tout simplement écouter le cours que d'écouter et de prendre des notes. Cependant, la qualité des résumés s'est avérée avoir une meilleure valeur prédictive de la performance que le sont les différences individuelles qui se manifestent pendant l'apprentissage. Cette étude contribue aux précédentes en intégrant la recherche sur le résumé et l'apprentissage qui a lieu pendant les cours, ainsi qu'en fournissant de nouvelles idées sur le rôle de la prise de notes et son lien avec la mémoire de travail