5,454 research outputs found

    Federalism in Securities Regulation: A Brief Introduction and Reflection

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    Can Money Change Who We Are? Estimating the Effects of Unearned Income on Measures of Incentive-Enhancing Personality Traits

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    The importance of noncognitive childhood skills in predicting higher wages is well documented in economics. This paper studies the reverse. Using surveys of lottery winners, we analyze the effects of unearned income on the Big Five personality traits. After correcting for potential endogeneity problems from prize sizes, we find that unearned income improves traits that predict pro-social and cooperative behaviors, preferences for social contact, empathy, and gregariousness, and reduces individuals' tendency toward negative emotional states: known in economics literature as incentive-enhancing personality traits. Our results support the possibility of scope for later interventions to improve the personality traits of adults.noncognitive skills, personality traits, lottery winners, instrumental variables, unearned income

    In vitro characterization of cadmium and zinc uptake via the gastrointestinal tract of rainbow trout (Oncorhynchus mykiss): interactive effects and the influence of calcium

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    An in vitro gut sac technique was employed to study whether Cd and Zn uptake mechanisms in the gastro-intestinal tract of the rainbow trout are similar to those at the gills, where both metals are taken up via the Ca transport pathway. Metal accumulation in surface mucus, in the mucosal epithelium, and transport into the blood space were assayed using radiolabelled Cd or Zn concentrations of 50 mol L−1 in the luminal (internal) saline. Elevated luminal Ca (10 or 100 mmol L−1 versus 1 mmol L−1) reduced Cd uptake into all three phases by approximately 60% in the stomach, but had no effect in the anterior, mid, or posterior intestine. This finding is in accordance with recent in vivo evidence that Ca is taken up mainly via the stomach, and that high [Ca] diets inhibit Cd accumulation from the food specifically in this section of the tract. In contrast, 10 mmol L−1 luminal Ca had no effect on Zn transport in any section, whereas 100 mmol L−1 Ca stimulated Zn uptake, by approximately threefold, into all three phases in the stomach only. There was no influence of elevated luminal Zn (10 mmol L−1) on Cd uptake in the stomach or anterior intestine, or of high Cd (10 mmol L−1) on Zn uptake in these sections. However, high [Zn] stimulated Cd transport into the blood space but inhibited accumulation in the mucosal epithelium and/or mucus-binding in the mid and posterior intestine, whereas high [Cd] exerted a reciprocal effect in the mid-intestine only. We conclude that Cd uptake occurs via an important Ca-sensitive mechanism in the stomach which is different from that at the gills, while Cd transport mechanisms in the intestine are not directly Ca-sensitive. Zn uptake does not appear to involve Ca uptake pathways, in contrast to the gills. These results are discussed in the context of other possible Cd and Zn transport pathways, and the emerging role of the stomach as an organ of divalent metal uptake.Natural Sciences and Engineering Research Council of Canada CRD Program, the International Lead Zinc Research Organization, the International Zinc Association, the Nickel Producers Environmental Research Association, the International Copper Association, the Copper Development Association, Teck-Cominco, Xstrata (Noranda-Falconbridge), and Inc

    In vitro analysis of the bioavailability of six metals via the gastrointestinal tract of rainbow trout (Oncorhynchus mykiss)

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    An in vitro gut sac technique was used to compare the uptake rates of essential (copper, zinc and nickel) and non-essential metals (silver, cadmium and lead) at 50 mol L−1 each (a typical nutritive level in solution in chyme) in the luminal saline in four sections of the gastro-intestinal tract (stomach, anterior, mid and posterior intestines) of the freshwater rainbow trout. Cu, Zn, Cd and Ag exhibited similar regional patterns: on an area-specific basis, uptake rates for these metals were highest in the anterior intestine, lowest in the stomach, and approximately equal in the mid and posterior intestinal segments. When these rates were converted to a whole animal basis, the predominance of the anterior intestine increased because of its greater area, while the contribution of the stomach rose slightly to approach those of the mid and posterior intestines. However, for Pb and Ni, area-specific and whole organism transport rates were greatest in the mid (Pb) and posterior (Ni) intestines. Surprisingly, total transport rates did not differ appreciably among the essential and non-essential metals, varying only from 0.025 (Ag) to 0.050 nmol g−1 h−1 (Ni), suggesting that a single rate constant can be applied for risk assessment purposes. These rates were generally comparable to previously reported uptake rates from waterborne exposures conducted at concentrations 1–4 orders of magnitude lower, indicating that both routes are likely important, and that gut transporters operate with much lower affinity than gill transporters. Except for Ni, more metal was bound to mucus and/or trapped in the mucosal epithelium than was transported into the blood space in every compartment except the anterior intestine, where net transport predominated. Overall, mucus binding was a significant predictor of net transport rate for every metal except Cd, and the strongest relationship was seen for Pb.Natural Sciences and Engineering Research Council of Canada CRD Program, the International Lead Zinc Research Organization, the International Zinc Association, the Nickel Producers Environmental Research Association, the International Copper Association, the Copper Development Association, Teck-Cominco, NorandaFalconbridge, and Inc

    Confinement of the Sun's interior magnetic field: some exact boundary-layer solutions

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    High-latitude laminar confinement of the Sun's interior magnetic field is shown to be possible, as originally proposed by Gough and McIntyre (1998) but contrary to a recent claim by Brun and Zahn (A&A 2006). Mean downwelling as weak as 2x10^-6cm/s -- gyroscopically pumped by turbulent stresses in the overlying convection zone and/or tachocline -- can hold the field in advective-diffusive balance within a confinement layer of thickness scale ~ 1.5Mm ~ 0.002 x (solar radius) while transmitting a retrograde torque to the Ferraro-constrained interior. The confinement layer sits at the base of the high-latitude tachocline, near the top of the radiative envelope and just above the `tachopause' marking the top of the helium settling layer. A family of exact, laminar, frictionless, axisymmetric confinement-layer solutions is obtained for uniform downwelling in the limit of strong rotation and stratification. A scale analysis shows that the flow is dynamically stable and the assumption of laminar flow realistic. The solution remains valid for downwelling values of the order of 10^-5cm/s but not much larger. This suggests that the confinement layer may be unable to accept a much larger mass throughput. Such a restriction would imply an upper limit on possible internal field strengths, perhaps of the order of hundreds of gauss, and would have implications also for ventilation and lithium burning. The solutions have interesting chirality properties not mentioned in the paper owing to space restrictions, but described at http://www.atmos-dynamics.damtp.cam.ac.uk/people/mem/papers/SQBO/solarfigure.htmlComment: 6 pages, 3 figures, to appear in conference proceedings: Unsolved Problems in Stellar Physic

    Can money change who we are? estimating the effects of unearned income on measures of incentive-enhancing personality

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    The importance of noncognitive childhood skills in predicting higher wages is well documented in economics. This paper studies the reverse. Using surveys of lottery winners, we analyze the effects of unearned income on the Big Five personality traits. After correcting for potential endogeneity problems from prize sizes, we find that unearned income improves traits that predict pro-social and cooperative behaviors, preferences for social contact, empathy, and gregariousness, and reduces individuals' tendency toward negative emotional states: known in economics literature as incentive-enhancing personality traits. Our results support the possibility of scope for later interventions to improve the personality traits of adults

    Money or mental health : the cost of alleviating psychological distress with monetary compensation versus psychological therapy

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    Money is the default way in which intangible losses, such as pain and suffering, are currently valued and compensated in law courts. Economists have suggested that subjective well-being regressions can be used to guide compensation payouts for psychological distress following traumatic life events. We bring together studies from law, economic, psychology and medical journals to show that alleviating psychological distress through psychological therapy could be at least 32 times more cost effective than financial compensation. This result is not only important for law courts but has important implications for public health. Mental health is deteriorating across the world – improvements to mental health care might be a more efficient way to increase the health and happiness of our nations than pure income growth
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