Insights from Review and Content Analysis of Current COVID-19 Mobile Apps and Recommendations for Future Pandemics

A number of mobile health apps related to coronavirus infectious disease 2019 (COVID-19) have been developed, but research into app content analytics for effective surveillance and management is still in its preliminary stages. The present study aimed to identify the purpose and functions of the currently available COVID-19 apps using content analysis. The secondary aim was to propose directions for the future development of apps that aid infectious disease surveillance and control with a focus on enhancing the app content and quality. Prior to conducting an app search in the App Store and the Google Play Store, we reviewed previous studies on COVID-19 apps found in Google Scholar and PubMed to examine the main purposes of the apps. Using the five selected keywords based on the review, we searched the two app stores to retrieve eligible COVID-19 apps including those already addressed in the reviewed literature. We conducted descriptive and content analyses of the selected apps. We classified the purpose types of the COVID-19 apps into the following five categories: Information provision, tracking, monitoring, mental health management, and engagement. We identified 890 apps from the review articles and the app stores: 47 apps met the selection criteria and were included in the content analysis. Among the selected apps, iOS apps outnumbered Android apps, 27 apps were government-developed, and most of the apps were created in the United States. The most common function for the iOS apps (63.6%) and Android apps (62.5%) was to provide COVID-19-related knowledge. The most common function among the tracking apps was to notify users of contact with infected people by the iOS apps (40.9%) and Android apps (37.5%). About 29.5% of the iOS apps and 25.0% of the Android apps were used to record symptoms and self-diagnose. Significantly fewer apps targeted mental health management and engagement. Six iOS apps (6/44, 13.6%) and four Android apps (4/24, 16.7%) provided behavioral guidelines about the pandemic. Two iOS apps (2/44, 4.5%) and two Android apps (2/24, 8.3%) featured communication functions. The present content analysis revealed that most of the apps provided unilateral information and contact tracing or location tracking. Several apps malfunctioned. Future research and development of COVID-19 apps or apps for other emerging infectious diseases should address the quality and functional improvements, which should begin with continuous monitoring and actions to mitigate any technical errors

Scoring of Human Body-Balance Ability on Wobble Board Based on the Geometric Solution

Many studies have reported that the human body-balance ability was essential in the early detection and self-management of chronic diseases. However, devices to measure balance, such as motion capture and force plates, are expensive and require a particular space for installation as well as specialized knowledge for analysis. Therefore, this study aimed to propose and verify a new algorithm to score the human body-balance ability on the wobble board (HBBAWB), based on a geometric solution using a cheap and portable device. Although the center of gravity (COG), the projected point of the center of mass (COM) on the fixed ground, has been used as the index for the balance ability, generally, it was not proper to use the COG under the condition of no fixed environment. The reason was that the COG index did not include the information on the slope for the wobble. Thus, this study defined the new index as the perpendicular-projection point (PPP), which was the projected point of the COM on the tilted plane. The proposed geometric solution utilized the relationship among three points, the PPP, the COM, and the middle point between the two feet, via linear regression. The experimental results found that the geometric solution, which utilized the relationship between the three angles of the equivalent model, enabled us to score the HBBAWB

The complete mitochondrial genome of the longneck croaker, pseudotolithus typus Bleeker, 1863 from Sierra Leone

The complete mitochondrial DNA information of Pseudotolithus typus Bleeker, 1863, collected from Sierra Leone was determined using next-generation sequencing (NGS) and bioinfromatic analysis. Its mitogenome (16,504 bp) encoded the typical 13 protein-coding genes (PCGs), 2 ribosomal RNAs (12S & 16S), and 22 tRNAs. All 13 PCGs showed a standard start codon (ATG) but an unusual stop codon (AGA) was identified in COX1 gene. Except for ND6, all 12 PCGs were encoded on the light strand. Except for tRNASer-GCT, 21 tRNAs formed the typical clover-leaf structures. Phylogenetic analysis showed three mitochondrial genomes in the genus Pseudotolithus formed a clade distinct from the other species in the same family. The mitogenome of P. typus identified in this study exhibited 96.27% and 88.86% identity to T. typus in the Guinean water and P. elongatus, respectively. Additional mitogenome sequences of Pseudotolithus species will provide useful information for their scientific management in western African countries

Perovskite solar cells approaching 25% PCE using side chain terminated hole transport materials with low concentration in a non-halogenated solvent process

Synchronously achieving high power conversion efficiency (PCE) at low cost is a great challenge for the star hole transport material (HTM) spiro-OMeTAD-based perovskite solar cells (PSCs) because of their expense. Three side-chain modified HTMs, spiro-mF-V, -A, and -P, are designed and synthesized. The incorporation of side chains, such as vinyloxy, allyloxy, and propargyloxy, effectively improves the hole mobility and matches the energy levels with the perovskite layer. All three HTMs show a high PCE of 23.7, 23.80, and 24.85% for spiro-mF-V, -A, and -P using a non-halogenated solvent, such as toluene for eco-friendly PSC fabrication. Furthermore, spiro-mF-V, -A, and -P exhibit good solubility and homogeneous film with smooth surface morphologies in a non-halogenated solvent system. In particular, the obtained PCE values exceed 23.7% at a low concentration in a non-halogenated system, which is one-third that of the spiro-OMeTAD-based PSCs. To the best of the authors' knowledge, it is the highest reported PCE for HTMs using non-halogenated solvents in PSCs. These findings show that the side chain engineering technique can produce novel HTMs for low-cost, environmentally friendly solvent processing

Enhanced expression of neuronal nitric oxide synthase and phospholipase C-gamma 1 in regenerating murine neuronal cells by pulsed electromagnetic field

Pulsed electromagnetic field (PEMF) has been shown to improve the rate of peripheral nerve regeneration. In the present study we investigated the expression of neuronal nitric oxide synthase (nNOS) and phospholipase C-gamma1 (PLC-gamma1) in regenerating rat laryngeal nerves during the exposure to PEMF after surgical transection and reanastomosis. Axons were found to regenerate into the distal stump nearly twice faster in PEMF-exposed animals than in the control. Consistently, motor function was better recovered in PEMF-treated rats. The expression of nNOS and PLC-gamma1 was highly enhanced in the regenerated nervesopen272