Chinese red yeast rice (Monascus purpureus-fermented rice) promotes bone formation

<p>Abstract</p> <p>Background</p> <p>Statin can induce the gene expression of bone morphogenetic protein-2. Red yeast rice (RYR, <it>Hongqu</it>), <it>i.e</it>. rice fermented with <it>Monascus purpureus</it>, contains a natural form of statin. This study demonstrates the effects of RYR extract on bone formation.</p> <p>Methods</p> <p>Bone defects were created in the parietal bones of two New Zealand white rabbits. In the test animal, two defects were grafted with collagen matrix mixed with RYR extract. In the control animal, two defects were grafted with collagen matrix alone. UMR 106 cell line was used to test RYR extract <it>in vitro</it>. In the control group, cells were cultured for three durations (24 hours, 48 hours and 72 hours) without any intervention. In the RYR group, cells were cultured for the same durations with various concentrations of RYR extract (0.001 g/ml, 0.005 g/ml and 0.01 g/ml). Bicinchoninic acid (BCA) assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and alkaline phosphatase (ALP) assay were performed to measure total protein, mitochondrial activity and bone cell formation respectively.</p> <p>Results</p> <p>The test animal showed more formation of new bone in the defects than the control animal. RYR significantly increased the optical density in the MTT assay and ALP activity <it>in vitro</it>.</p> <p>Conclusion</p> <p>RYR extract stimulated new bone formation in bone defects <it>in vivo </it>and increased bone cell formation <it>in vitro</it>.</p

Self correction of anterior crossbite: a case report

A 9-year-old Chinese boy presented with an anterior crossbite, no treatment was performed at that time because the incisors have open root apices. The crossbite self-corrected after one year. This case demonstrated that an anterior crossbite may self-correct without treatment

Diagnosis and management of root resorption by erupting canines using cone-beam computed tomography and fixed palatal appliance: a case report

<p>Abstract</p> <p>Introduction</p> <p>Resorption of the root of the maxillary incisors during ectopic eruption of the maxillary canines is not an uncommon phenomenon, and must be considered in all patients with seriously diverging eruption of the maxillary canines.</p> <p>Case presentation</p> <p>We report on the diagnosis and treatment of a 10-year-old Chinese boy with severe crowding and risk of root resorptions caused by impacted canines in the upper arch and reverse overjet. With the aid of cone-beam computed tomography, the upper right canine crown of our patient was positioned in close proximity to the right lateral incisor while the left canine crown was hitting the root apex of the left lateral incisor. To avoid any progress of root resorption, use of an upper fixed palatal appliance with torquing spring to move the root of lateral incisors away from the canines, plus extraction of upper primary first molars, was selected as an interceptive treatment.</p> <p>Conclusions</p> <p>Careful planning is crucial to avoid any complication through orthodontic treatment and to reduce the treatment time and cost.</p

Orthodontic traction of impacted canine using magnet: a case report

A 15 year and 1 month old Chinese female with palatally impacted upper left canine was successfully treated with an upper removable appliance with a magnet incorporated to provide orthodontic traction force. This case report indicates the possibility of using magnetic force as a safe, effective and comfortable way for orthodontic traction

Repair of a defect following the removal of an impacted maxillary canine by orthodontic tooth movement: a case report

This case report describes a 13-year-old boy with alveolar bony defect resulted from surgical removal of impacted upper canine transposed in the anterior region. The boy had a normal occlusion with malposition of upper central and lateral incisors. The treatment objectives were to align teeth, close spaces by mesial movement of the buccal segments in the upper jaw to repair bone loss. Fixed appliance with palatal root torque was used for the mesial movements, levelling, and alignment of teeth

The effects of Rhizoma Curculiginis and Rhizoma Drynariae extracts on bones

© 2007 Wong et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

The modified two-by-one fixed orthodontic appliance for bodily movement of canine: a case report

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

Orthodontic tooth movement enhancing bony apposition in alveolar bony defect: a case report

Introduction: Prevalence of complications from orthognathic surgery is relatively low but if it happens it is vital to manage the post complication bony defect appropriately. Case Presentation: This case report describes a 20-year-old gentleman who suffered from a complication from a bimaxillary orthognathic surgery. A bone grafting was carried out to repair the bony defect from the surgery but it was unsuccessful. A non-invasive technique employing the use of very light orthodontic force with a laceback stainless steel ligature is described and a successful space closure with an improvement in the periodontal condition and bone apposition has been shown. Conclusion: This technique can be considered if orthodontic tooth movement is needed across a deficient alveolar ridge. © 2009 Hibino and Wong; licensee BioMed Central Ltd.published_or_final_versio

Photomicrograph of bone defect grafted with extract in collagen matrix on day 14

<p><b>Copyright information:</b></p><p>Taken from "The effects of and extracts on bones"</p><p>http://www.cmjournal.org/content/2/1/13</p><p>Chinese Medicine 2007;2():13-13.</p><p>Published online 19 Dec 2007</p><p>PMCID:PMC2206024.</p><p></p> New bone can be seen spanning the defect. Some collagen matrix (C) remained at the center of the bone defect (Periodic acid-Schiff stain; original magnification × 40)

Photomicrograph of bone defect grafted with collagen matrix (positive control) on day 14

<p><b>Copyright information:</b></p><p>Taken from "The effects of and extracts on bones"</p><p>http://www.cmjournal.org/content/2/1/13</p><p>Chinese Medicine 2007;2():13-13.</p><p>Published online 19 Dec 2007</p><p>PMCID:PMC2206024.</p><p></p> No bone could be seen across the defect except a little new bone near the ends of the host bone (H). Collagen matrix (C) remained across the bone defect (Periodic acid-Schiff stain, original magnification × 40)