1 research outputs found
Radiation-induced anaplastic astrocytoma following treatment of medulloblastoma
We hereby report a case of a 10-year-old girl in whom neurosurgery was performed for cerebellar vermis medulloblastoma
in April 2000. After resection the patient underwent chemotherapy followed by radiotherapy, receiving
53.07 Gy to posterior fossa and 35.07 Gy to the rest of the craniospinal axis. In 2012, she was diagnosed with
anaplastic astrocytoma, which was located within the high-dose region. Surgical resection of the tumour was performed.
Postoperatively, the patient received radiation therapy (50.4 Gy) with concurrent temozolomide, followed
by 6 cycles of adjuvant temozolomide. Five years after the diagnosis of anaplastic astrocytoma, the patient remains
asymptomatic