Baseline characteristics of the study and validation groups.

<p>Mean values with standard deviations are given, unless otherwise specified.</p><p>* CC homozygotes vs. G-allele carriers.</p><p>^{^} derivation vs. validation group.</p><p>^#Smoking status in the derivation group was available in 453 patients (in 213 CC homozygotes and 240 G-allele carriers). It was available in all patients from the validation group.</p><p>NA- data not available.</p><p>Baseline characteristics of the study and validation groups.</p

Kaplan-Meier survival curves for CC homozygotes and G-allele carriers of the rs12526453 SNP in the derivation group (panel A) and in the validation group (panel B).

<p>The differences between the groups were statistically significant (p = 0.017 in the derivation group and p = 0.031 in the validation group, Cox`s F test).</p

A univariate analysis for 3-year mortality in the validation cohort.

<p>For all parameters only admission values were used.</p><p>A univariate analysis for 3-year mortality in the validation cohort.</p

The expression data from microarrays experiments for <i>NLRP2</i> gene on admission (A) (p = 0.00001) and discharge (B) (p = 0.0003).

<p>The points present the expression level from all analyzed patients with CC genotype (red) and CG/GG (blue).</p

A univariate analysis for 5-year mortality in the derivation cohort.

<p>For all parameters only admission values were used.</p><p>A univariate analysis for 5-year mortality in the derivation cohort.</p

Principal component analysis of PBMCs gene expression profiles.

<p>PCA plot shows the first three principal components of microarray data in respect to their correlation.</p