230 research outputs found

    Fully quantum-mechanical treatment of proton-hydrogen scattering

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    © Published under licence by IOP Publishing Ltd. A fully quantum-mechanical convergent close-coupling approach to proton collisions with atomic hydrogen has been developed. Cross sections for target ionisation and electron capture by the projectile have been calculated in the energy range from 20 keV to 1 MeV. Calculated electron capture cross sections are in good agreement with the experiment, however for ionisation discrepancies between theory and experiment at intermediate energies still remain

    Design Case Retrieval by Generic Representations

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    Baidu, Weibo and Renren: The Global Political Economy of Social Media in China

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    The task of this work is to conduct a global political-economic analysis of China's major social media platforms in the context of transformations of the Chinese economy. It analyses Chinese social media's commodity and capital form. It compares the political economy of Baidu (search engine), Weibo (microblog) and Renren (social networking site) to the political economy of the US platforms Google (search engine), Twitter (microblog) and Facebook (social networking site) in order to analyse differences and commonalities. The comparative analysis focuses on aspects such as profits, the role of advertising, the boards of directors, shareholders, financial market values, terms of use and usage policies. The analysis is framed by the question to which extent China has a capitalist or socialist economy

    The Phrenic Component of Acute Schizophrenia – A Name and Its Physiological Reality

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    Decreased heart rate variability (HRV) was shown for unmedicated patients with schizophrenia and their first-degree relatives, implying genetic associations. This is known to be an important risk factor for increased cardiac mortality in other diseases. The interaction of cardio-respiratory function and respiratory physiology has never been investigated in the disease although it might be closely related to the pattern of autonomic dysfunction. We hypothesized that increased breathing rates and reduced cardio-respiratory coupling in patients with acute schizophrenia would be associated with low vagal function. We assessed variability of breathing rates and depth, HRV and cardio-respiratory coupling in patients, their first-degree relatives and controls at rest. Control subjects were investigated a second time by means of a stress task to identify stress-related changes of cardio-respiratory function. A total of 73 subjects were investigated, consisting of 23 unmedicated patients, 20 healthy, first-degree relatives and 30 control subjects matched for age, gender, smoking and physical fitness. The LifeShirt®, a multi-function ambulatory device, was used for data recording (30 minutes). Patients breathe significantly faster (p<.001) and shallower (p<.001) than controls most pronouncedly during exhalation. Patients' breathing is characterized by a significantly increased amount of middle- (p<.001), high- (p<.001), and very high frequency fluctuations (p<.001). These measures correlated positively with positive symptoms as assessed by the PANSS scale (e.g., middle frequency: r = 521; p<.01). Cardio-respiratory coupling was reduced in patients only, while HRV was decreased in patients and healthy relatives in comparison to controls. Respiratory alterations might reflect arousal in acutely ill patients, which is supported by comparable physiological changes in healthy subjects during stress. Future research needs to further investigate these findings with respect to their physiological consequences for patients. These results are invaluable for researchers studying changes of biological signals prone to the influence of breathing rate and rhythm (e.g., functional imaging)

    Natural History of Tuberculosis: Duration and Fatality of Untreated Pulmonary Tuberculosis in HIV Negative Patients: A Systematic Review

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    Background The prognosis, specifically the case fatality and duration, of untreated tuberculosis is important as many patients are not correctly diagnosed and therefore receive inadequate or no treatment. Furthermore, duration and case fatality of tuberculosis are key parameters in interpreting epidemiological data. Methodology and Principal Findings To estimate the duration and case fatality of untreated pulmonary tuberculosis in HIV negative patients we reviewed studies from the pre-chemotherapy era. Untreated smear-positive tuberculosis among HIV negative individuals has a 10-year case fatality variously reported between 53% and 86%, with a weighted mean of 70%. Ten-year case fatality of culture-positive smear-negative tuberculosis was nowhere reported directly but can be indirectly estimated to be approximately 20%. The duration of tuberculosis from onset to cure or death is approximately 3 years and appears to be similar for smear-positive and smear-negative tuberculosis. Conclusions Current models of untreated tuberculosis that assume a total duration of 2 years until self-cure or death underestimate the duration of disease by about one year, but their case fatality estimates of 70% for smear-positive and 20% for culture-positive smear-negative tuberculosis appear to be satisfactory
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