Rex Quondam, Rexque Futurus: Arthurian Legends As Indicators of British National Identity Throughout History

By looking at the texts of Arthurian legends such as Sir Thomas Malory\u27s Le Morte d\u27Arthur, T.H. White\u27s The Once & Future King, and Marion Zimmer Bradley\u27s The Mists of Avalon, one can gain a historical perspective of the time in which each work was written. Through this historical perspective and by looking at each author\u27s personal life, a picture of Great Britain\u27s national identity at the time of writing can be seen. As such, the Arthurian Cycle can be used to exemplify British national identity throughout history

Responsibilities of Employers toward Mentally Disabled Persons under the Americans with Disabilities Act

This article discusses the standards of the American with Disabilities Act with respect to accommodating mental illness in the workplace. It argues that the ADA definitions are not precise enough in apprising employers of what their obligations are regarding mentally ill persons in the workplace. It additionally suggests revising the statue and regulations to achieve this goal

Responsibilities of Employers toward Mentally Disabled Persons under the Americans with Disabilities Act

This article will discuss the standards of the ADA with respect to accommodating mental illness in the workplace. It will argue the ADA definitions are not precise enough to apprising employers of what are their obligations regarding mentally ill persons in the workplace. It will additionally make suggestions for revising the statute and regulations to achieve this goal. In reaching its conclusion, this article will discuss popular conceptions about mental illness, and the current statutory framework of the ADA. Representative case law will be considered within the context of these topics. The article will ultimately suggest that fairness to both employers and employees can only be achieved by clearer definitions within the statute and an overt acknowledgment that mental disabilities are not necessarily synonymous with physical disabilities

New Pharmacological Agents to Aid Smoking Cessation and Tobacco Harm Reduction: What has been Investigated and What is in the Pipeline?

A wide range of support is available to help smokers to quit and aid attempts at harm reduction, including three first-line smoking cessation medications: nicotine replacement therapy, varenicline and bupropion. Despite the efficacy of these, there is a continual need to diversify the range of medications so that the needs of tobacco users are met. This paper compares the first-line smoking cessation medications to: 1) two variants of these existing products: new galenic formulations of varenicline and novel nicotine delivery devices; and 2) twenty-four alternative products: cytisine (novel outside of central and eastern Europe), nortriptyline, other tricyclic antidepressants, electronic cigarettes, clonidine (an anxiolytic), other anxiolytics (e.g. buspirone), selective 5-hydroxytryptamine (5-HT) reuptake inhibitors, supplements (e.g. St John’s wort), silver acetate, nicobrevin, modafinil, venlafaxine, monoamine oxidase inhibitors (MAOI), opioid antagonist, nicotinic acetylcholine receptors (nAChR) antagonists, glucose tablets, selective cannabinoid type 1 receptor antagonists, nicotine vaccines, drugs that affect gamma-aminobutyric acid (GABA) transmission, drugs that affect N-methyl-D-aspartate receptors (NMDA), dopamine agonists (e.g. levodopa), pioglitazone (Actos; OMS405), noradrenaline reuptake inhibitors, and the weight management drug lorcaserin. Six criteria are used: relative efficacy, relative safety, relative cost, relative use (overall impact of effective medication use), relative scope (ability to serve new groups of patients), and relative ease of use (ESCUSE). Many of these products are in the early stages of clinical trials, however, cytisine looks most promising in having established efficacy and safety and being of low cost. Electronic cigarettes have become very popular, appear to be efficacious and are safer than smoking, but issues of continued dependence and possible harms need to be considered

Mutagenicity of black pepper (Piper nigrum) in Drosophila melanogaster

Includes bibliographical references.Two-day-old adults of Drosophila melanoqaster (stock OR/y⁺YB[^s]) were raised on a balanced Drosophila medium to which powdered black pepper had been added, in order to test for rates of black pepper-induced mutagenicity. Two different concentrations of black pepper were used, the higher being just below the lethal dose of the larvae. Two-day-old males which had been fed for their entire lives on the test mixtures were mated to y²w[^sp] females. The males were transferred to a different group of virgin females every three days for two consecutive periods, resulting in two broods. Offspring were scored to determine the frequency of chromosome loss or breakage. The addition of black pepper did not induce a significant increase in chromosomal aberrations. The two concentrations of black pepper in the diet were also tested for the induction of sex-linked recessive lethals by the use of Oregon R males and Muller-5 females, employing the above brood methods. Again, the obtained data showed no evidence of mutagenicity.M.S. (Master of Science