41 research outputs found
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and bemcitabine in vitro and in huma tumor xenografts
Get PDF5-Fluorouracil/ leucovorin-induced inhibition of thymidylate synthase in normal tissues of mouse and man
Get PDFAntitumour activity, toxicity and inhibition of thymidylate syntahse of prolonged administration of 5-fluorouracil in mice
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Selective protection by uridine of growth inhibition by 5-fluorouracil (5FU) mediated by 5FU incorporation into RNA, but not the thymidylate synthase mediated growth inhibition by 5FU-leucovorin
No full textCross resistance to thymidylate synthase inhibitors in p-glycoprotein and non-p-glycoprotein cell lines
No full textEvaluation of immunohistochemical staining and activity of thymidylate synthase in cell lines
No full textThe interval between methotrexate and leucovorin determines the efficacy of 5-flurorouracil modulation in vitro and in vivo
No full textEffect of leucovorin on 5-fluorouracil induced inhibition of thymidylate synthase in patients with colon cancer. Purine and Pyrimidin Metabolism in Man VII
No full textMolecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed
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