Onboard sampling of the rockfish and lingcod commerical passenger fishing vessel industry in northern and central California, 1992

In 1992 fishery technicians sampled 230 commercial passenger fishing vessel (CPFV) trips targeting rockfish and lingcod from the port areas of Fort Bragg, Bodega Bay, San Francisco, Monterey, and Morro Bay. The skippers of 44 vessels, and 2,190 anglers, cooperated in the study. Species composition by port area and month, catch-per-unit-effort, mean length, and length frequency of lingcod and the 18 most frequently observed rockfish species are presented, as well as fishing effort relative to time, depth, and distance from port. Total catch estimates based on unadjusted and adjusted logbook records are summarized. Average catch of kept fish per angler day was 12.6 and average catch of kept fish per angler hour was 4.0. A continuing trend of an increasing frequency of trips to deep (> 40 fm) locations was observed in the Bodega Bay, San Francisco, and Monterey areas. Bodega Bay and San Francisco showed the highest frequency of trips to distant locations. Sixty species comprised of 29,731 fish were observed caught during the study. Rockfish comprised 93.5% by number of the total observed catch. The five most frequently observed species were blue, yellowtail, widow and rosy rockfishes, and bocaccio, with lingcod ranking eighth. CPFV angler success, as determined by catch per angler hour, generally increased in all ports in 1992 compared to previous 1988-91 data (Reilly et al. 1993). However, port-specific areas of major concern were identified for chilipepper, lingcod, and black rockfish, and to a lesser extent brown, canary, vermilion, yelloweye, widow and greenspotted rockfishes. These areas of concern included steadily declining catch rate, steadily declining mean length, and/or a high percentage of sexually immature fish in the sampled catch. Recent sampling of the commercial hook-and-line fishery in northern and central California indicates that most rockfishes taken by CPFV anglers are also harvested commercially. (105pp.

Comparison of prenatal and postnatal ontogeny: cranial allometry in the African striped mouse (Rhabdomys pumilio)

The relationship between prenatal and postnatal ontogenetic allometry is poorly known, and empirical studies documenting prenatal allometry are few, precluding an understanding of changes in growth patterns during life history and their relation to proximal, physiological, and ultimate evolutionary variables. In this study I compare prenatal and postnatal ontogenetic allometry of the cranium in a cleared and stained developmental series of the African striped mouse (Rhabdomys pumilio). Eighteen cranial measurements, reflecting the dimensions of individual elements, were analyzed using bivariate and multivariate estimates of allometry and methods of matrix comparison. Prenatal allometry is characterized in R. pumilio by a relative rapid lengthening of cranial elements, particularly the frontal, parietal, basisphenoid, premaxilla, and palatine, as evidenced by larger bivariate allometric coefficients (>30% increase) and, across all variables measured, a greater proportion of cranial elements growing with a positive allometry than in the postnatal period. Growth dynamics are found to shift for measurements of several elements including the parietal, frontal, and palatine, indicating a nonlinearity of ontogenetic allometry with respect to birth; similar shifts have been found between prenatal and postnatal growth for some regions of the human cranium. Application of common principal component analyses, a generalized extension of principal component analysis, revealed that the prenatal and postnatal matrices shared a highly similar structure, further quantified by high correlations (>0.78) using the random skewers method of matrix comparison. These results indicate a close correspondence between morphology-based variance structures over the course of ontogeny in R. pumili

The Structure and Function of Urban Pharmacies: Visits to Community Pharmacies in Inner-City Chicago

Visits were made to 21 pharmacies in two poor neighborhoods on the west side of Chicago and interviews conducted with pharmacists-in-charge. The objective of the study was to provide a comprehensive description of the function, capabilities, and problems of urban pharmacy. We present results on the structure and function of these inner-city pharmacies. The pharmacies fit one of three structural forms: chain, independent, or medical center. The majority of respondents viewed the function of the inner-city pharmacy as patient-centered but also identified several barriers to effective patient communication. The results suggest that inner-city physicians and pharmacists should communicate with patients more often and in ways that patients understand. Also, Medicaid and other drug insurance programs should develop patient information networks and coverage packages intended to maximize patient health status

Coming Soon to ACRL | NEC: A New Open Access Repository for Conference Proceedings and Other Materials

This poster describes a new open access repository being developed to store and disseminate digital materials arising from ACRL | NEC conferences and SIG events. Come learn more about the repository and how your ACRL | NEC group can participate

SbcCD regulation and localization in Escherichia coli

The SbcCD complex and its homologues play important roles in DNA repair and in the maintenance of genome stability. In Escherichia coli, the in vitro functions of SbcCD have been well characterized, but its exact cellular role remains elusive. This work investigates the regulation of the sbcDC operon and the cellular localization of the SbcC and SbcD proteins. Transcription of the sbcDC operon is shown to be dependent on starvation and RpoS protein. Overexpressed SbcC protein forms foci that colocalize with the replication factory, while overexpressed SbcD protein is distributed through the cytoplasm

The histone demethylase enzymes KDM3A and KDM4B co-operatively regulate chromatin transactions of the estrogen receptor in breast cancer

Many estrogen receptor (ER)-positive breast cancers develop resistance to endocrine therapy but retain canonical receptor signalling in the presence of selective ER antagonists. Numerous co-regulatory proteins, including enzymes that modulate the chromatin environment, control the transcriptional activity of the ER. Targeting ER co-regulators has therefore been proposed as a novel therapeutic approach. By assessing DNA-binding dynamics in ER-positive breast cancer cells, we have identified that the histone H3 lysine 9 demethylase enzymes, KDM3A and KDM4B, co-operate to regulate ER activity via an auto-regulatory loop that facilitates the recruitment of each co-activating enzyme to chromatin. We also provide evidence that suggests that KDM3A primes chromatin for deposition of the ER pioneer factor FOXA1 and recruitment of the ER-transcriptional complex, all prior to ER recruitment, therefore establishing an important mechanism of chromatin regulation involving histone demethylases and pioneer factors, which controls ER functionality. Importantly, we show via global gene-expression analysis that a KDM3A/KDM4B/FOXA1 co-regulated gene signature is enriched for pro-proliferative and ER-target gene sets, suggesting that abrogation of this network could be an efficacious therapeutic strategy. Finally, we show that depletion of both KDM3A and KDM4B has a greater inhibitory effect on ER activity and cell growth than knockdown of each individual enzyme, suggesting that targeting both enzymes represents a potentially efficacious therapeutic option for ER-driven breast cancer

Quantum entanglement between electronic and vibrational degrees of freedom in molecules

We consider the quantum entanglement of the electronic and vibrational degrees of freedom in molecules with a tendency towards double welled potentials using model coupled harmonic diabatic potential-energy surfaces. The von Neumann entropy of the reduced density matrix is used to quantify the electron-vibration entanglement for the lowest two vibronic wavefunctions in such a bipartite system. Significant entanglement is found only in the region in which the ground vibronic state contains a density profile that is bimodal (i.e., contains two separate local minima). However, in this region two distinct types of entanglement are found: (1) entanglement that arises purely from the degeneracy of energy levels in the two potential wells and which is destroyed by slight asymmetry, and (2) entanglement that involves strongly interacting states in each well that is relatively insensitive to asymmetry. These two distinct regions are termed fragile degeneracy-induced entanglement and persistent entanglement, respectively. Six classic molecular systems describable by two diabatic states are considered: ammonia, benzene, semibullvalene, pyridine excited triplet states, the Creutz-Taube ion, and the radical cation of the "special pair" of chlorophylls involved in photosynthesis. These chemically diverse systems are all treated using the same general formalism and the nature of the entanglement that they embody is elucidated