Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Chris McGregor: now's the time

Photocopied article from the newspaper Melody Maker about Chris McGregor's music and its influence on the new European jazz style. There is a portrait of Chris McGregor with this article

Chris McGregor with a horse.

Black and white photo (front and back) of Chris McGregor with a horse at Milton Court Farm, Alfriston in 1972. There is a stamp of the photographer's details and a sticker with Chris McGregor's postal address in France

Johnny Dyani at Blue Notes London debut in 1965.

Black and white photo (front and back) of Johnny Dyani playing the double bass at Blue Notes London debut at ICA in Dover Street, 26th of April 1965

Chris McGregor and Johnny Dyani at Blue Notes London debut in April 1965

Black and white photo (front and back) of Chris McGregor and Johnny Dyani playing at Blue Notes London debut at the International Communication Association (ICA) in Dover Street, the 26th of April 1965

Dudu Pukwana at home

Black and white photo (front and back) of Dudu Pukwana at home (Peckham, London) holding his saxophone

Mongezi Feza and Barre Phillips playing their instruments

Black and white photo (front and back) of Mongezi Feza playing the trumpet and Barre Phillips playing the double bass at a concert in Cambridge, 2nd of March 1969. A stamp at the back of the photo indicates the photographer's details

Chris McGregor posing outside

Black and white photo (front and back) of Chris McGregor posing outside with cows in the background, in Alfriston, Sussex (England) in 1972

Harry Miller playing double bass.

Black and white photo (front and back) of Harry Miller playing double bass. There is a stamp on the back indicating name, address and registration number of the photographer

Barbara and Dudu Pukwana at home

Black and white photo (front and back) of Barbara and Dudu Pukwana at home in London, the 27th of July 196