8,134 research outputs found

    Epacris limbata sp. nov., a localised heath from eastern Tasmania

    Get PDF
    A description is given of Epacris limbata sp. nov., a new species of heath known from three locations on Tasmania's eastern coast. Notes on taxonomic affinities and habitat of the species are presented

    Reconnaissance survey of a glaucous eucalypt near Louisa Bay, southwestern Tasmania

    Get PDF
    Stands of a glaucous eucalypt in the vicinity of Louisa Bay, southwestern Tasmania, which has affinities to Eucalyptus tenuiramis (Series Piperitae), were surveyed in order to determine their taxonomic status and record aspects of their population ecology. Two main populations were observed in scattered stands among predominantly moorland vegetation at the Red Point Hills and Louisa Plains. One stand from each population was accessed for detailed study. Contiguous plots located along transects across the copses were used to record changes in population status, floristics and site conditions. Individuals of the glaucous eucalypt were small in stature and frequently malleeform near the moorland boundary, but were taller (10-12 m) and straight with single, slender main stems toward the centre of the copse. The Red Point Hills stand comprised a larger number of smaller individuals than the Louisa Plains stand and had been subject to at least three fires in the last 65 years, whereas only one fire had occurred on the Louisa Plains in the same period. These observations have implications for fire management: an appropriate regime, which encourages regeneration around the stand margins rather than increasing the edge-effects, needs to be devised. Given the geographic discontinuity with Eucalyptus tenuiramis, the southwestern copses may represent a relict dry sclerophyll community that was once contiguous with eastern Tasmania during the height of the last glaciation

    The comparative hemodynamic efficacy of lower limb muscles using transcutaneous electrical stimulation.

    Get PDF
    Circulation in the limbs can be augmented using transcutaneous electrical stimulation devices. The optimum muscle stimulation sites for enhancement of vascular hemodynamic parameters have not been identified.Seven suitable anatomic sites were identified within the right leg. Twelve healthy participants were recruited (mean age, 23.1 ± 3 years; body mass index, 23.1 ± 3 kg/m(2)). Muscles were stimulated by transcutaneous bipolar electrodes at a current twice their motor threshold, at 1 Hz, for 5 minutes. Hemodynamic ultrasound measurements were taken from the right femoral vein. Laser Doppler measurements from the feet of the stimulated and nonstimulated sides were obtained. Baseline measurements were compared with readings after 5 minutes of stimulation, with device active. Discomfort experienced for stimulation of each muscle was rated out of 100.Hemodynamic changes displayed large intersubject variation, with no muscle statistically superior to the others. All muscles increased peak velocity; contraction of medial gastrocnemius increased time-averaged maximum velocity and volume flow. All muscles increased foot fluximetry (P < .05). Discomfort correlated weakly with current applied. Tibialis anterior and vastus lateralis were most tenable.Transcutaneous stimulation increases hemodynamic parameters significantly, locally and systemically. No optimum stimulation site has been identified, and it is limited by comfort and variability in the subjects response. Gastrocnemius, tibialis anterior, and vastus lateralis all provoke large changes in hemodynamic parameters, but clinical efficacy in disease prevention and management has not been explored

    The comparative haemodynamic efficacy of lower limb muscles using transcutaneous electrical stimulation

    Get PDF
    BACKGROUND: Circulation in the limbs can be augmented using transcutaneous electrical stimulation devices. The optimum muscle stimulation sites for enhancement of vascular hemodynamic parameters have not been identified. METHODS: Seven suitable anatomic sites were identified within the right leg. Twelve healthy participants were recruited (mean age, 23.1 ± 3 years; body mass index, 23.1 ± 3 kg/m(2)). Muscles were stimulated by transcutaneous bipolar electrodes at a current twice their motor threshold, at 1 Hz, for 5 minutes. Hemodynamic ultrasound measurements were taken from the right femoral vein. Laser Doppler measurements from the feet of the stimulated and nonstimulated sides were obtained. Baseline measurements were compared with readings after 5 minutes of stimulation, with device active. Discomfort experienced for stimulation of each muscle was rated out of 100. RESULTS: Hemodynamic changes displayed large intersubject variation, with no muscle statistically superior to the others. All muscles increased peak velocity; contraction of medial gastrocnemius increased time-averaged maximum velocity and volume flow. All muscles increased foot fluximetry (P < .05). Discomfort correlated weakly with current applied. Tibialis anterior and vastus lateralis were most tenable. CONCLUSIONS: Transcutaneous stimulation increases hemodynamic parameters significantly, locally and systemically. No optimum stimulation site has been identified, and it is limited by comfort and variability in the subject's response. Gastrocnemius, tibialis anterior, and vastus lateralis all provoke large changes in hemodynamic parameters, but clinical efficacy in disease prevention and management has not been explored

    Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases.

    Get PDF
    BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been identified as potentially important in the development of emphysema. However, the relationship between MMPs and emphysema sub-type is unknown. We investigated the role of MMPs and their inhibitors in the development of emphysema sub-types by quantifying levels and determining relationships with these sub-types in mild-moderate COPD patients and ex/current smokers with preserved lung function. METHODS: Twenty-four mild-moderate COPD and 8 ex/current smokers with preserved lung function underwent high resolution CT and distinct emphysema sub-types were quantified using novel local histogram-based assessment of lung density. We analysed levels of MMPs and tissue inhibitors of MMPs (TIMPs) in bronchoalveolar lavage (BAL) and assessed their relationship with these emphysema sub-types. RESULTS: The most prevalent emphysema subtypes in COPD subjects were mild and moderate centrilobular (CLE) emphysema, while only small amounts of severe centrilobular emphysema, paraseptal emphysema (PSE) and panlobular emphysema (PLE) were present. MMP-3, and -10 associated with all emphysema sub-types other than mild CLE, while MMP-7 and -8 had associations with moderate and severe CLE and PSE. MMP-9 also had associations with moderate CLE and paraseptal emphysema. Mild CLE occurred in substantial quantities irrespective of whether airflow obstruction was present and did not show any associations with MMPs. CONCLUSION: Multiple MMPs are directly associated with emphysema sub-types identified by CT imaging, apart from mild CLE. This suggests that MMPs play a significant role in the tissue destruction seen in the more severe sub-types of emphysema, whereas early emphysematous change may be driven by a different mechanism. TRIAL REGISTRATION: Trial registration number NCT01701869

    Cerebral time domain near-infrared spectroscopy of people with multiple sclerosis: A feasibility study

    Get PDF
    We present a feasibility study on the use of a time domain NIRS instrument, named MAESTROS, to explore the cerebral optical parameters and physiology of people with multiple sclerosis
    • …
    corecore