1,216 research outputs found

    Of Civil Wrongs and Rights: \u3cem\u3eKiyemba v. Obama\u3c/em\u3e and the Meaning of Freedom, Separation of Powers, and the Rule of Law Ten Years After 9/11

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    This article is about the rise and fall of continued adherence to the rule of law, proper application of the separation of powers doctrine, and the meaning of freedom for a group of seventeen Uighurs—a Turkic Muslim ethnic minority whose members reside in the Xinjiang province of China—who had been held at the Guantanamo Bay Naval Base since 2002. Most scholars regard the trilogy of Hamdi v. Rumsfeld, Hamdan v. Rumsfeld, and Boumediene v. Bush as demonstrating the Supreme Court’s willingness to uphold the rule of law during the war on terror. The recent experience of the Uighurs suggest that this commitment is either waning or was never as strong as scholars thought. About a year and a half before the tenth anniversary of the terrorist attacks of September 11, 2001, the United States Supreme Court was primed to hear oral arguments in the Uighurs’ case known as Kiyemba v. Obama. The issue in this case was whether the Uighurs, who were concededly being detained illegally, would be released from Guantanamo Bay. As a result of the government’s latest delay tactics, the Court never heard the merits of the case. Had it done so, the Court, arguably, would have established the contours of a constitutionally required habeas remedy for foreign nationals whose indefinite detention had been judicially declared illegal and no other option but release into the continental interior of the United States is possible. The Court’s dismissal of the Uighurs previously granted cert petition thus signaled the beginning of the end of the Court’s landmark “war-on–terror” line of precedential cases culminating in the evisceration of its 2008 seminal case of Boumediene v. Bush. With the D. C. Circuit Court of Appeals decision now reinstated in which the court had held in 2009 that habeas courts had no jurisdiction to order the release of foreign nationals under such circumstances because it was an immigration case triggering the political branches’ plenary power over which such matters are largely immune from judicial intervention. But Kiyemba v. Obama is not an immigration case. The Uighurs were brought here involuntarily as a result of the government’s counterterrorism policies, the implementation of which the Court had declared unlawful over the course of a four year period beginning with Rasul v. Bush in 2004. The D.C. Circuit Court holding, which still stands, was erroneous because the Uighurs never sought to immigrate to this country; their filing of writs of habeas corpus placed the matter solidly in the area of granting constitutionally required habeas relief which a habeas court has jurisdiction to decide. Through political machinations and influences at all levels of government, however, the Supreme Court has more recently decided to end its role of protecting the individual rights of Guantanamo Bay detainees with a series of denials of cert.-petitions without a single dissent authored to voice concerns about the beginning of the end of the Republic Benjamin Franklin once said we had but only if we could keep it. And although most of the original group of Uighurs has subsequently been relocated to other countries, the two still remaining have now entered their second decade of unlawful detention

    Interprofessional Education: Current State in Psychology Training

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    Healthcare reform has led to the consideration of interprofessional team-based, collaborative care as a way to provide comprehensive, high-quality care to patients and families. Interprofessional education is the mechanism by which the next generation health professional workforce is preparing for the future of health care-team-based, collaborative care. This literature review explored the extent and content of published studies documenting Interprofessional Education (IPE) activities with psychology trainees across learner level. A systematic review following PRISMA guidelines was conducted of studies describing IPE involving psychology learners. Electronic databases (MEDLINE, CINAHL, PsychINFO, and EMBASE) were searched for the following terms: inter/multi-professional education/practice, inter/multidisciplinary education/practice, and psychology/psychologists. Thirty-seven articles were identified that included psychology in clinical outcome studies or other reviews of interprofessional education initiatives. The review addresses the nature of current IPE learning activities, the impact of IPE activities on participating trainees, opportunities for, and challenges of, involving psychology trainees in IPE, and future directions for research. This review illuminates the relative paucity of the literature about IPE in psychology training. Given the trend toward increasing team-based collaborative care, the limited inclusion of psychology in the IPE literature is concerning. The next generation of health professional trainees is learning about, from, and with each other with the objective of building collaboration and teamwork. Given the few articles documenting psychology trainees\u27 involvement in IPE, future health professionals quite possibly will have limited understanding of, and contact with, psychologists. Our findings are a call to action for greater psychology involvement in IPE

    Proteinaceous Pheromone Homologs Identified from the Cloacal Gland Transcriptome of a Male Axolotl, Ambystoma mexicanum

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    Abstract Pheromones play an important role in modifying vertebrate behavior, especially during courtship and mating. Courtship behavior in urodele amphibians often includes female exposure to secretions from the cloacal gland, as well as other scent glands. The first vertebrate proteinaceous pheromone discovered, the decapeptide sodefrin, is a female attracting pheromone secreted by the cloacal gland of male Cynops pyrrhogaster. Other proteinaceous pheromones in salamanders have been shown to elicit responses from females towards conspecific males. The presence and levels of expression of proteinaceous pheromones have not been identified in the family Ambystomatidae, which includes several important research models. The objective of this research was therefore to identify putative proteinaceous pheromones from male axolotls, Ambystoma mexicanum, as well as their relative expression levels. The results indicate that axolotls possess two different forms of sodefrin precursor-like factor (alpha and beta), as well as a putative ortholog of plethodontid modulating factor. The beta form of sodefrin precursor-like factor was amongst the most highly expressed transcripts within the cloacal gland. The ortholog of plethodontid modulating factor was expressed at a level equivalent to the beta sodefrin precursor-like factor. The results are from a single male axolotl; therefore, we are unable to assess how representative our results may be. Nevertheless, the presence of these highly expressed proteinaceous pheromones suggests that male axolotls use multiple chemical cues to attract female conspecifics. Behavioral assays would indicate whether the putative protein pheromones elicit courtship activity from female axolotls

    Microbial impacts on 99mTc migration through sandstone under highly alkaline conditions relevant to radioactive waste disposal

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    Geological disposal of intermediate level radioactive waste in the UK is planned to involve the use of cementitious materials, facilitating the formation of an alkali-disturbed zone within the host rock. The biogeochemical processes that will occur in this environment, and the extent to which they will impact on radionuclide migration, are currently poorly understood. This study investigates the impact of biogeochemical processes on the mobility of the radionuclide technetium, in column experiments designed to be representative of aspects of the alkali-disturbed zone. Results indicate that microbial processes were capable of inhibiting 99mTc migration through columns, and X-ray radiography demonstrated that extensive physical changes had occurred to the material within columns where microbiological activity had been stimulated. The utilisation of organic acids under highly alkaline conditions, generating H2 and CO2, may represent a mechanism by which microbial processes may alter the hydraulic conductivity of a geological environment. Column sediments were dominated by obligately alkaliphilic H2-oxidising bacteria, suggesting that the enrichment of these bacteria may have occurred as a result of H2 generation during organic acid metabolism. The results from these experiments show that microorganisms are able to carry out a number of processes under highly alkaline conditions that could potentially impact on the properties of the host rock surrounding a geological disposal facility for intermediate level radioactive waste

    The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells

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    The eukaryotic translation initiation factor 2α (eIF2α) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as activating ligands of yeast GCN2 is supported experimentally. However, mouse GCN2 activation has recently been observed in circumstances associated with ribosome stalling with no global increase in uncharged tRNAs. We report on a mammalian CHO cell-based CRISPR-Cas9 mutagenesis screen for genes that contribute to ISR activation by amino acid starvation. Disruption of genes encoding components of the ribosome P-stalk, uL10 and P1, selectively attenuated GCN2-mediated ISR activation by amino acid starvation or interference with tRNA charging without affecting the endoplasmic reticulum unfolded protein stress-induced ISR, mediated by the related eIF2α kinase PERK. Wildtype ribosomes isolated from CHO cells, but not those with P-stalk lesions, stimulated GCN2-dependent eIF2α phosphorylation in vitro. These observations support a model whereby lack of a cognate charged tRNA exposes a latent capacity of the ribosome P-stalk to activate GCN2 in cells and help explain the emerging link between ribosome stalling and ISR activation
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