Ethnic Differences in Bladder Cancer Survival

ObjectiveTo examine trends in bladder cancer survival among whites, blacks, Hispanics, and Asian/Pacific Islanders in the United States over a 30-year period. Racial disparities in bladder cancer outcomes have been documented with poorer survival observed among blacks. Bladder cancer outcomes in other ethnic minority groups are less well described.MethodsFrom the Surveillance, Epidemiology and End Results cancer registry data, we identified patients diagnosed with transitional cell carcinoma of the bladder between 1975 and 2005. This cohort included 163,973 white, 7731 black, 7364 Hispanic, and 5934 Asian/Pacific Islander patients. We assessed the relationship between ethnicity and patient characteristics. Disease-specific 5-year survival was estimated for each ethnic group and for subgroups of stage and grade.ResultsBlacks presented with higher-stage disease than whites, Hispanics, and Asian/Pacific Islanders, although a trend toward earlier-stage presentation was observed in all groups over time. Five-year disease-specific survival was consistently worse for blacks than for other ethnic groups, even when stratified by stage and grade. Five-year disease-specific survival was 82.8% in whites compared with 70.2% in blacks, 80.7% in Hispanics, and 81.9% in Asian/Pacific Islanders. There was a persistent disease-specific survival disadvantage in black patients over time that was not seen in the other ethnic groups.ConclusionEthnic disparities in bladder cancer survival persist between whites and blacks, whereas survival in other ethnic minority groups appears similar to that of whites. Further study of access to care, quality of care, and treatment decision making among black patients is needed to better understand these disparities

Perspectives on Risk Perceptions

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72341/1/j.1539-6924.1981.tb01409.x.pd

A planet within the debris disk around the pre-main-sequence star AU Microscopii

AU Microscopii (AU Mic) is the second closest pre main sequence star, at a distance of 9.79 parsecs and with an age of 22 million years. AU Mic possesses a relatively rare and spatially resolved3 edge-on debris disk extending from about 35 to 210 astronomical units from the star, and with clumps exhibiting non-Keplerian motion. Detection of newly formed planets around such a star is challenged by the presence of spots, plage, flares and other manifestations of magnetic activity on the star. Here we report observations of a planet transiting AU Mic. The transiting planet, AU Mic b, has an orbital period of 8.46 days, an orbital distance of 0.07 astronomical units, a radius of 0.4 Jupiter radii, and a mass of less than 0.18 Jupiter masses at 3 sigma confidence. Our observations of a planet co-existing with a debris disk offer the opportunity to test the predictions of current models of planet formation and evolution.Comment: Nature, published June 24th [author spelling name fix

The Hawaii Infrared Parallax Program. III. 2MASS J0249-0557 c:A Wide Planetary-mass Companion to a Low-mass Binary in the β Pic Moving Group

We have discovered a wide planetary-mass companion to the $\beta$ Pic moving group member 2MASSJ02495639-0557352 (M6 VL-G) using CFHT/WIRCam astrometry from the Hawaii Infrared Parallax Program. In addition, Keck laser guide star adaptive optics aperture-masking interferometry shows that the host is itself a tight binary. Altogether, 2MASSJ0249-0557ABc is a bound triple system with an $11.6^{+1.0}_{-1.3}$ $M_{\rm Jup}$ object separated by $1950\pm200$ AU (40") from a relatively close ($2.17\pm0.22$ AU, 0.04") pair of $48^{+12}_{-13}$ $M_{\rm Jup}$ and $44^{+11}_{-14}$ $M_{\rm Jup}$ objects. 2MASSJ0249-0557AB is one of the few ultracool binaries to be discovered in a young moving group and the first confirmed in the $\beta$ Pic moving group ($22\pm6$ Myr). The mass, absolute magnitudes, and spectral type of 2MASSJ0249-0557 c (L2 VL-G) are remarkably similar to those of the planet $\beta$ Pic b (L2, $13.0^{+0.4}_{-0.3}$ $M_{\rm Jup}$). We also find that the free-floating object 2MASSJ2208+2921 (L3 VL-G) is another possible $\beta$ Pic moving group member with colors and absolute magnitudes similar to $\beta$ Pic b and 2MASSJ0249-0557 c. $\beta$ Pic b is the first directly imaged planet to have a "twin," namely an object of comparable properties in the same stellar association. Such directly imaged objects provide a unique opportunity to measure atmospheric composition, variability, and rotation across different pathways of assembling planetary-mass objects from the same natal material.Comment: Accepted to AJ, only change is color scheme of figure