Mass measurement in boosted decay systems at hadron colliders

We report a new possibility of using the \mct2 (Constransverse mass) variable for mass measurement in single step decay chains involving missing particles with moderate transverse momentum. We show that its experimental feasibility is enhanced compared to the corresponding \mt2-kink method. We apply this method to reconstruct a pair of chargino decay chains.Comment: 6 pages, 12 figures, published in PRD, http://link.aps.org/doi/10.1103/PhysRevD.84.03501

Discriminating spin through quantum interference

Many of the proposed solutions to the hierarchy and naturalness problems postulate new `partner' fields to the standard model particles. Determining the spins of these new particles will be critical in distinguishing among the various possible SM extensions, yet proposed methods rely on the underlying models. We propose a new model-independent method for spin measurements which takes advantage of quantum interference among helicity states. We demonstrate that this method will be able to discriminate scalar particles from higher spin states at the ILC, and discuss application to higher spins and possible uses at the LHC.Comment: 11 pages, 11 figure

High-throughput chromatin accessibility profiling at single-cell resolution.

Here we develop a high-throughput single-cell ATAC-seq (assay for transposition of accessible chromatin) method to measure physical access to DNA in whole cells. Our approach integrates fluorescence imaging and addressable reagent deposition across a massively parallel (5184) nano-well array, yielding a nearly 20-fold improvement in throughput (up to ~1800 cells/chip, 4-5 h on-chip processing time) and library preparation cost (~81¢ per cell) compared to prior microfluidic implementations. We apply this method to measure regulatory variation in peripheral blood mononuclear cells (PBMCs) and show robust, de novo clustering of single cells by hematopoietic cell type

Charged Higgs Bosons in Naturally Aligned Two Higgs Doublet Models at the LHC

Measurements of a Higgs boson at the Large Hadron Collider (LHC) have become increasingly consistent with the predictions of the Standard Model (SM). This fact puts severe constraints on many potential low-energy extensions of the Higgs sector of the SM. In the well-known Two Higgs Doublet Model (2HDM), an `alignment limit' of parameters readily furnishes one SM-like scalar, and can be achieved naturally through an underlying symmetry. Among the other physical states of the 2HDM, a charged scalar $H^\pm$ would provide striking evidence of new physics if observed. We propose a novel technique for the observation of the process $pp\to t b H^\pm \to t\bar{t}b\bar{b}$ in the dileptonic decay channel at the LHC. The reconstruction of events in this channel is complicated by multiple $b$-jets and unobserved neutrinos in the final state. To determine the neutrino momenta, we implement a neutrino weighting procedure to study, for the first time, the $t\bar{t}b\bar{b}$ signature. We further train a pair of boosted decision trees to reconstruct and classify signal events. We determine the resulting reach within the context of naturally aligned 2HDMs, such as the Maximally Symmetric Two Higgs Doublet Model (MS-2HDM). By testing at the integrated luminosity of 150 fb$^{-1}$ achieved in Run 2 of the LHC, we find that this channel may restrict the parameter space of a Type-II MS-2HDM with charged Higgs masses as high as 680 GeV.Comment: 23 pages, 13 figures. Additional studies of backgrounds and comparison with existing searches added, some clarifications made, reference adde

Large Mixing Angles From Many Right-Handed Neutrinos

A beautiful understanding of the smallness of the neutrino masses may be obtained via the seesaw mechanism, whereby one takes advantage of the key qualitative distinction between the neutrinos and the other fermions: right-handed neutrinos are gauge singlets, and may therefore have large Majorana masses. The standard seesaw mechanism, however, does not address the apparent lack of hierarchy in the neutrino masses compared to the quarks and charged leptons, nor the large leptonic mixing angles compared to the small angles of the CKM matrix. In this paper, we will show that the singlet nature of the right-handed neutrinos may be taken advantage of in one further way in order to solve these remaining problems: Unlike particles with gauge interactions, whose numbers are constrained by anomaly cancellation, the number of gauge singlet particles is essentially undetermined. If large numbers of gauge singlet fermions are present at high energies - as is suggested, for example, by various string constructions - then the effective low energy neutrino mass matrix may be determined as a sum over many distinct Yukawa couplings, with the largest ones being the most important. This can reduce hierarchy, and lead to large mixing angles. Assuming a statistical distribution of fundamental parameters, we will show that this scenario leads to a good fit to low energy phenomenology, with only a few qualitative assumptions guided by the known quark and lepton masses. The scenario leads to predictions of a normal hierarchy for the neutrino masses, and a value for the |m_ee| mass matrix element of about 1-6 meV.Comment: 22 pages, 7 figures; v2: rare bug in diagonalization algorithm corrected- little quantitative impact on result