Dose-related influences of chronic alcohol exposure on nuclear protein expression (A) and DNA-binding activity (B) of PPARγ in CATH.a neurons.

<p>Values are means ± SE for 6 wells in each group. *P<0.05 vs. 0 mM alcohol.</p

Total infarct volume (A) and neurological score (B) at 24 hours of reperfusion after a 90-minute MCAO in nonalcohol-fed and 1% alcohol-fed mice treated without and with rosiglitazone or GW9662.

<p>Values are means ± SE for 6 mice in each group. *P<0.05 vs. Nonalcohol. #P<0.05 vs. Without Treatment.</p

Effect of chronic exposure of 1 mM alcohol on apoptosis in CATH.a neurons following a 2-hour OGD/24-hour reoxygenation.

<p>Values are means ± SE for 6 wells in each group. *P<0.01 vs. Without OGD/reperfusion. *P<0.05 vs. Nonalcohol.</p

Nuclear protein expression (A) and DNA-binding activity (B) of PPARγ in parietal cortex punched at the peri-infarct and the contralateral corresponding areas of nonalcohol-fed and 1% alcohol-fed mice following a 90-minute MCAO/24-hour reperfusion.

<p>Values are means ± SE for 6 mice in each group. *P<0.001 vs. Nonalcohol. #P<0.001 vs. Without MCAO/reperfusion.</p