Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists

Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data. We thank John Low for carrying out the Cambridge Database survey.Peer reviewedPublisher PD

SAR investigations of glaciers in northwestern North America

The objective of this project was to investigate the utility of satellite synthetic aperture radar (SAR) imagery for measurement of geophysical parameters on Alaskan glaciers relevant to their mass balance and dynamics, including: (1) the positions of firn lines (late-summer snow lines); (2) surface velocities on fast-flowing (surging) glaciers, and also on slower steady-flow glaciers; and (3) the positions and changes in the positions of glacier termini. Preliminary studies of topography and glacier surface velocity with SAR interferometry have also been carried out. This project was motivated by the relationships of multi-year to decadal changes in glacier geometry to changing climate, and the probable significant contribution of Alaskan glaciers to rising sea level

Ethyl 2-(5-bromo-2-iodo­anilino)cyclo­pent-1-ene-1-carboxyl­ate

Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collection.Peer reviewedPublisher PD

Syntheses and Crystal Structures of Three Chiral Oxazolidinones with Different Ring Conformations

Funding: This research received no external funding. Acknowledgments: We thank the EPSRC National Crystallography Centre (University of Southampton) for the X-ray data collections.Peer reviewedPublisher PD

Understanding the remarkable difference in liquid crystal behaviour between secondary and tertiary amides : the synthesis and characterisation of new benzanilide-based liquid crystal dimers

Open Access via the RSC Open Access AgreementPeer reviewedPublisher PD

Crystal structures of four indole derivatives with a phenyl substituent at the 2-position and a carbonyl group at the 3-position : the C(6) N-H⋯O chain remains the same, but the weak reinforcing inter-actions are different

Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data.Peer reviewedPublisher PD

Weak interactions in the crystal structures of two indole derivatives

Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data.Peer reviewedPublisher PD

Spatially Resolving a Starburst Galaxy at Hard X-ray Energies: NuSTAR, Chandra, AND VLBA Observations of NGC 253

Prior to the launch of NuSTAR, it was not feasible to spatially resolve the hard (E > 10 keV) emission from galaxies beyond the Local Group. The combined NuSTAR dataset, comprised of three ~165 ks observations, allows spatial characterization of the hard X-ray emission in the galaxy NGC 253 for the first time. As a follow up to our initial study of its nuclear region, we present the first results concerning the full galaxy from simultaneous NuSTAR, Chandra, and VLBA monitoring of the local starburst galaxy NGC 253. Above ~10 keV, nearly all the emission is concentrated within 100" of the galactic center, produced almost exclusively by three nuclear sources, an off-nuclear ultraluminous X-ray source (ULX), and a pulsar candidate that we identify for the first time in these observations. We detect 21 distinct sources in energy bands up to 25 keV, mostly consisting of intermediate state black hole X-ray binaries. The global X-ray emission of the galaxy - dominated by the off-nuclear ULX and nuclear sources, which are also likely ULXs - falls steeply (photon index >~ 3) above 10 keV, consistent with other NuSTAR-observed ULXs, and no significant excess above the background is detected at E > 40 keV. We report upper limits on diffuse inverse Compton emission for a range of spatial models. For the most extended morphologies considered, these hard X-ray constraints disfavor a dominant inverse Compton component to explain the {\gamma}-ray emission detected with Fermi and H.E.S.S. If NGC 253 is typical of starburst galaxies at higher redshift, their contribution to the E > 10 keV cosmic X-ray background is < 1%.Comment: 20 pages, 14 figures, accepted for publication in Ap