Different hypoxia levels in intracranial tumours of untreated control mice in the same experiment.

<p><b>(</b>A) and (C): day 14 after implantation; (B) and (D): day 16 after implantation. Photographs are from one experiment with 4 mice (A-D).</p

Statistical data for Fig 5.

<p>Statistical data for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0184250#pone.0184250.g005" target="_blank">Fig 5</a>.</p

Effect of PFC/carbogen and carbogen alone on hypoxia in intracranial mouse glioma tumours.

<p>Animals were divided into groups of 5 mice each. A. Untreated control mice; B. Mice exposed to PFC emulsions; C. Mice exposed to carbogen and D. Mice exposed to both PFC emulsions and carbogen. Tumor-bearing mice were injected IV with 1.5cc/kg of a 40% PFC emulsion and hypoxia was measured using pimonidazole-HCL (PIM). Mice that received carbogen (95%O₂/5%CO₂) for 1h were placed in an air-tight chamber. Photos are representative of 3 separate experiments.</p

Effect of PFC/carbogen and carbogen alone on hypoxia in subcutaneous mouse glioma tumours.

<p>Animals were divided into groups of 5 mice each. (A) Untreated control mice; (B) mice exposed to both PFC emulsions and carbogen and (C) mice exposed to carbogen alone. Tumor-bearing mice were injected IV with 1.5cc/kg of a 40% PFC emulsion and hypoxia was measured using pimonidazole-HCL (PIM). Mice that received carbogen (95%O₂/5%CO₂) for 1h were placed in an air-tight chamber. Photos are representative of 2 separate experiments with 5 mice in each group.</p