MOESM3 of Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

Additional file 3.  Brain tissue (70–100 mg) from all BLT HIV-infected and uninfected animals was used to extract RNA. The RNA was used to quantify host genes (A) human CD163 (B) human IP10 (C) human MX2 and (D) mouse f4/80

MOESM4 of Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain

Additional file 4.  Differentiated THP-1 cells were infected with HIV-1 YU-2 and SF162. DNA was extracted from infected cells and used to establish the integration assay (A). Host genes expression from patients 1 and 2 compared to uninfected controls measured by quantitative RT-PCR for, (B) CD163, (C) IL6, (D) TNFA, (E) APOBEC3G, (F) MX2, (G) MX1 and (H) BST2