5,456 research outputs found
Lattice Refining LQC and the Matter Hamiltonian
In the context of loop quantum cosmology, we parametrise the lattice
refinement by a parameter, , and the matter Hamiltonian by a parameter,
. We then solve the Hamiltonian constraint for both a self-adjoint, and
a non-self-adjoint Hamiltonian operator. Demanding that the solutions for the
wave-functions obey certain physical restrictions, we impose constraints on the
two-dimensional, , parameter space, thereby restricting the types
of matter content that can be supported by a particular lattice refinement
model.Comment: 15 pages, 3 figures, revtex style; amended version to match
publication in Phys. Rev.
Lattice Refining Loop Quantum Cosmology and Inflation
We study the importance of lattice refinement in achieving a successful
inflationary era. We solve, in the continuum limit, the second order difference
equation governing the quantum evolution in loop quantun cosmology, assuming
both a fixed and a dynamically varying lattice in a suitable refinement model.
We thus impose a constraint on the potential of a scalar field, so that the
continuum approximation is not broken. Considering that such a scalar field
could play the role of the inflaton, we obtain a second constraint on the
inflationary potential so that there is consistency with the CMB data on large
angular scales. For a inflationary model, we combine the two
constraints on the inflaton potential to impose an upper limit on , which is
severely fine-tuned in the case of a fixed lattice. We thus conclude that
lattice refinement is necessary to achieve a natural inflationary model.Comment: 12 pages, RevTex Two minor changes to match version to appear in
Physical Review
EEG analytics for early detection of autism spectrum disorder: a data-driven approach
Autism spectrum disorder (ASD) is a complex and heterogeneous disorder, diagnosed on the basis of behavioral symptoms during the second year of life or later. Finding scalable biomarkers for early detection is challenging because of the variability in presentation of the disorder and the need for simple measurements that could be implemented routinely during well-baby checkups. EEG is a relatively easy-to-use, low cost brain measurement tool that is being increasingly explored as a potential clinical tool for monitoring atypical brain development. EEG measurements were collected from 99 infants with an older sibling diagnosed with ASD, and 89 low risk controls, beginning at 3 months of age and continuing until 36 months of age. Nonlinear features were computed from EEG signals and used as input to statistical learning methods. Prediction of the clinical diagnostic outcome of ASD or not ASD was highly accurate when using EEG measurements from as early as 3 months of age. Specificity, sensitivity and PPV were high, exceeding 95% at some ages. Prediction of ADOS calibrated severity scores for all infants in the study using only EEG data taken as early as 3 months of age was strongly correlated with the actual measured scores. This suggests that useful digital biomarkers might be extracted from EEG measurements.This research was supported by National Institute of Mental Health (NIMH) grant R21 MH 093753 (to WJB), National Institute on Deafness and Other Communication Disorders (NIDCD) grant R21 DC08647 (to HTF), NIDCD grant R01 DC 10290 (to HTF and CAN) and a grant from the Simons Foundation (to CAN, HTF, and WJB). We are especially grateful to the staff and students who worked on the study and to the families who participated. (R21 MH 093753 - National Institute of Mental Health (NIMH); R21 DC08647 - National Institute on Deafness and Other Communication Disorders (NIDCD); R01 DC 10290 - NIDCD; Simons Foundation)Published versio
Effects of Alternative Cropping Patterns and Management Decisions on Soil Erosion and Revenue, Region VII, North Dakota
This report focuses on the economic impact of selected agricultural management policies and the corresponding effect upon soil erosion.Farm Management, Land Economics/Use,
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Shear-induced damped oscillations in an epithelium depend on actomyosin contraction and E-cadherin cell adhesion.
Shear forces between cells occur during global changes in multicellular organization during morphogenesis and tissue growth, yet how cells sense shear forces and propagate a response across a tissue is unknown. We found that applying exogenous shear at the midline of an epithelium induced a local, short-term deformation near the shear plane, and a long-term collective oscillatory movement across the epithelium that spread from the shear-plane and gradually dampened. Inhibiting actomyosin contraction or E-cadherin trans-cell adhesion blocked oscillations, whereas stabilizing actin filaments prolonged oscillations. Combining these data with a model of epithelium mechanics supports a mechanism involving the generation of a shear-induced mechanical event at the shear plane which is then relayed across the epithelium by actomyosin contraction linked through E-cadherin. This causes an imbalance of forces in the epithelium, which is gradually dissipated through oscillatory cell movements and actin filament turnover to restore the force balance across the epithelium
Constraining the Noncommutative Spectral Action via Astrophysical Observations
The noncommutative spectral action extends our familiar notion of commutative
spaces, using the data encoded in a spectral triple on an almost commutative
space. Varying a rather simple action, one can derive all of the standard model
of particle physics in this setting, in addition to a modified version of
Einstein-Hilbert gravity. Thus, noncommutative geometry provides a geometric
interpretation of particle physics coupled to curvature. In this letter we use
observations of pulsar timings, assuming that no deviation from General
Relativity has been observed, to constrain the gravitational sector of this
theory. Thus, we directly constrain noncommutative geometry, a potential grand
unified theory of physics, via astrophysical observations. Whilst the bounds on
the coupling constants remain rather weak, they are comparable to existing
bounds on deviations from General Relativity in other settings and are likely
to be further constrained by future observations.Comment: 5 pages; slightly shorter version to match the one will appear in
Phys. Rev. Let
Letters between A. C. Nelson and William Kerr
Letters concerning a position in the art department at Utah Agricultural College
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