31 research outputs found

    Very Long Baseline Neutrino Oscillation Experiment for Precise Measurements of Mixing Parameters and CP Violating Effects

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    We analyze the prospects of a feasible, Brookhaven National Laboratory based, very long baseline (BVLB) neutrino oscillation experiment consisting of a conventional horn produced low energy wide band beam and a detector of 500 kT fiducial mass with modest requirements on event recognition and resolution. Such an experiment is intended primarily to determine CP violating effects in the neutrino sector for 3-generation mixing. We analyze the sensitivity of such an experiment. We conclude that this experiment will allow determination of the CP phase δCP\delta_{CP} and the currently unknown mixing parameter θ13\theta_{13}, if sin22θ130.01\sin ^2 2 \theta_{13} \geq 0.01, a value 15\sim 15 times lower than the present experimental upper limit. In addition to θ13\theta_{13} and δCP\delta_{CP}, the experiment has great potential for precise measurements of most other parameters in the neutrino mixing matrix including Δm322\Delta m^2_{32}, sin22θ23\sin^2 2\theta_{23}, Δm212×sin2θ12\Delta m^2_{21}\times \sin 2 \theta_{12}, and the mass ordering of neutrinos through the observation of the matter effect in the νμνe\nu_\mu \to \nu_e appearance channel.Comment: 12 pages, 10 figure

    Measurement of the solar neutrino capture rate with gallium metal

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    The solar neutrino capture rate measured by the Russian-American Gallium Experiment (SAGE) on metallic gallium during the period January 1990 through December 1997 is 67.2 (+7.2-7.0) (+3.5-3.0) SNU, where the uncertainties are statistical and systematic, respectively. This represents only about half of the predicted Standard Solar Model rate of 129 SNU. All the experimental procedures, including extraction of germanium from gallium, counting of 71Ge, and data analysis are discussed in detail.Comment: 34 pages including 14 figures, Revtex, slightly shortene

    Measurement of the solar neutrino capture rate by SAGE and implications for neutrino oscillations in vacuum

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    The Russian-American solar neutrino experiment has measured the capture rate of neutrinos on metallic gallium in a radiochemical experiment at the Baksan Neutrino Observatory. Eight years of measurement give the result 67.2 (+7.2,-7.0) (+3.5,-3.0) SNU, where the uncertainties are statistical and systematic, respectively. The restrictions these results impose on vacuum neutrino oscillation parameters are given

    Measurement of the solar neutrino capture rate with gallium metal

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    The solar neutrino capture rate measured by the Russian-American Gallium Experiment (SAGE) on metallic gallium during the period January 1990 through December 1997 is 67.2 (+7.2-7.0) (+3.5-3.0) SNU, where the uncertainties are statistical and systematic, respectively. This represents only about half of the predicted Standard Solar Model rate of 129 SNU. All the experimental procedures, including extraction of germanium from gallium, counting of 71Ge, and data analysis are discussed in detail

    The russian-american gallium experiment (sage) cr neutrino source measurement

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    The solar neutrino capture rate measured by SAGE is well below that predicted by solar models. To check the overall experimental efficiency, we exposed 13 tonnes of Ga metal to a reactor-produced 517 kCi source of 51Cr. The ratio of the measured production rate to that predicted from the source activity is 0.95+/-0.11statstat+0.05/-0.08systsyst. This agreement verifies that the experimental efficiency is measured correctly, establishes that there are no unknown systematic errors at the 10% level, and provides considerable evidence for the reliability of the solar neutrino measurement. © 1996 The American Physical Society

    Measurement of the response of a gallium metal solar neutrino experiment to neutrinos from a 51Cr source

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    The neutrino capture rate measured by the Russian-American Gallium Experiment is well below that predicted by solar models. To check the response of this experiment to low-energy neutrinos, a 517 kCi source of 51Cr was produced by irradiating 512.7 g of 92.4%-enriched 50Cr in a high-flux fast neutron reactor. This source, which mainly emits monoenergetic 747-keV neutrinos, was placed at the center of a 13.1 tonne target of liquid gallium and the cross section for the production of 71Ge by the inverse beta decay reaction was measured to be (5.55 +/- 0.60 (stat.) +/- 0.32 (syst.)) x 10^(-45) cm^2. The ratio of this cross section to the theoretical cross section of Bahcall for this reaction is 0.95 +/- 0.12 (exp.) +/- 0.03 (theor.) and to the cross section of Haxton is 0.87 +/- 0.11 (exp.) +/- 0.09 (theor.). This good agreement between prediction and observation implies that the overall experimental efficiency for the solar neutrino measurements is correctly determined and provides considerable evidence for the reliability of the solar neutrino measurement.Comment: 20 pages including figures in two column forma

    Finite proliferative lifespan in vitro of a human breast cancer cell strain isolated from a metastatic lymph node

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    We recently described culture conditions that allow proliferation of metastatic human breast cancer cells from biopsy specimens of certain patient samples. These conditions resulted in the development of an immortalized cell strain designated SUM-44PE. These same culture conditions were used to isolate a human breast cancer cell strain from a metastatic lymph node of a separate breast cancer patient. The SUM-16LN human breast cancer cells isolated from this specimen were cultured either in serum-free medium or serum-containing medium supplemented with insulin and hydrocortisone. Unlike the SUM-44PE cells that have proliferated in culture continuously for over two years, SUM-16LN cells proliferated in culture for approximately 200 days and underwent 15 to 20 population doublings before undergoing cell senescence. No cells of this strain proliferated beyond passage 8. SUM-16LN cells were keratin-19 positive and had an aneuploid karyotype. These cells overexpressed p53 protein and had an amplified epidermal growth factor (EGF) receptor gene that resulted in high level expression of tyrosine phosphorylated EGF receptor protein. Despite the presence of high levels of tyrosine phosphorylated EGF receptor in these cells, they proliferated in serum-free, EGF-free medium and did not secrete detectable levels of EGF-like mitogenic growth factor. In addition, these cells were potently growth inhibited by all concentrations of exogenous EGF tested and by the neutralizing EGF receptor antibody Mab 425. These results suggest that the high level of tyrosine phosphorylated EGF receptor present in these cells is the direct result of receptor overexpression and not the result of the presence of a simulatory ligand. Thus, SUM-16LN represents a human breast cancer cell strain that exhibited genetic and cellular characteristics of advanced human breast cancer cells. Nevertheless, these cells exhibited a finite proliferative lifespan in culture, suggesting that cellular immortalization is not a phenotype expressed by all human breast cancer cells.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44199/1/10549_2004_Article_BF00666588.pd
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