Automatic ontology mapping for agent communication

Agent communication languages such as ACL and KQML provide a standard for agent communication. These languages enable an agent to specify the intention and the content of a message as well as the protocol, the language, and the ontology that are used. For the protocol and the language some standards are available and should be known by the communicating agents. The ontology used in a communication depends on the subject of the communication. Since the number of subjects is almost infinite and since the concepts used for a subject can be described by different ontologies, the development of generally accepted standards will take a long time. This lack of standardization, which hampers communication and collaboration between agents, is known as the interoperability problem. To overcome the interoperability problem, agents must be able to establish a mapping between their ontologies. This paper investigates a new approach to the interoperability problem. The proposed approach requires neither a correspondence between concepts used in the ontologies nor a correspondence between the structure of the ontologies. It only requires that some instances of the subject about which the agents try to communicate are known by both agents.economics of technology ;

Automated extraction of potential migraine biomarkers using a semantic graph

Problem Biomedical literature and databases contain important clues for the identification of potential disease biomarkers. However, searching these enormous knowledge reservoirs and integrating findings across heterogeneous sources is costly and difficult. Here we demonstrate how semantically integrated knowledge, extracted from biomedical literature and structured databases, can be used to automatically identify potential migraine biomarkers. Method We used a knowledge graph containing more than 3.5 million biomedical concepts and 68.4 million relationships. Biochemical compound concepts were filtered and ranked by their potential as biomarkers based on their connections to a subgraph of migraine-related concepts. The ranked results were evaluated against the results of a systematic literature review that was performed manually by migraine researchers. Weight points were assigned to these reference compounds to indicate their relative importance. Results Ranked results automatically generated by the knowledge graph were highly consistent with results from the manual literature review. Out of 222 reference compounds, 163 (73%) ranked in the top 2000, with 547 out of the 644 (85%) weight points assigned to the reference compounds. For reference compounds that were not in the top of the list, an extensive error analysis has been performed. When evaluating the overall performance, we obtained a ROC-AUC of 0.974. Discussion Semantic knowledge graphs composed of information integrated from multiple and varying sources can assist researchers in identifying potential disease biomarkers

Benefits and problems of electronic information exchange as perceived by health care professionals: an interview study

<p>Abstract</p> <p>Background</p> <p>Various countries are currently implementing a national electronic patient record (n-EPR). Despite the assumed positive effects of n-EPRs, their overall adoption remains low and meets resistance from health care providers. This study aims to increase our understanding of health care providers' attitude towards the n-EPR, by investigating their perceptions of the benefits and problems of electronic information exchange in health care and the n-EPR in particular.</p> <p>Methods</p> <p>The study was conducted in three Dutch health care settings: acute care, diabetes care, and ambulatory mental health care. Two health care organisations were included per setting. Between January and June 2010, interviews were conducted with 17 stakeholders working in these organisations. Relevant themes were deduced by means of thematic qualitative analysis.</p> <p>Results</p> <p>Health care providers perceived electronic information exchange to promote the efficiency and quality of care. The problems they perceived in electronic information exchange mainly concerned the confidentiality and safety of information exchange and the reliability and quality of patient data. Many problems perceived by health care providers did not specifically apply to the n-EPR, but to electronic information exchange in general.</p> <p>Conclusions</p> <p>The implementation of the Dutch n-EPR has mainly followed a top-down approach, thereby neglecting the fact that the perceptions and preferences of its users (health care providers) need to be addressed in order to achieve successful implementation. The results of this study provide valuable suggestions about how to promote health care providers' willingness to adopt electronic information exchange, which can be useful for other countries currently implementing an n-EPR. Apart from providing information about the benefits and usefulness of electronic information exchange, efforts should be focused on minimising the problems as perceived by health care providers. The safety and confidentiality of electronic information exchange can be improved by developing tools to evaluate the legitimacy of access to electronic records, by increasing health care providers' awareness of the need to be careful when using patient data, and by measures to limit access to sensitive patient data. Improving health care providers' recording behaviour is important to improve the reliability and quality of electronically exchanged patient data.</p

Domain Independent Learning of Ontology Mappings

This paper proposes a domain independent method for handling interoperability problems by learning a mapping between ontologies. The learning method is based on exchanging instances of concepts that are defined in the ontologies. The method starts with identifying pairs of instances of concepts denoting the same entity in the world using information retrieval techniques, followed by proposing and evaluating mappings between the ontologies using the pairs of instances. For each step of this method, the likelihood that a decision is correct is taken into account. Important benefits of the method are that (a) no domain knowledge is required, and (b) the structures of ontologies between which a mapping must be established, play no role

Agents for Market-Based Computational-Resource Allocation

Distributed computing is a well-known approach to perform computationally intensive tasks. A problem inherent to this approach is the allocation of tasks to machines. This problem can be successfully addressed with a market mechanism. The article presents a comparison between two market mechanisms for an agent-based trading platform for computational resources. The platform consists of the following agents: (A) management agents (the directory facilitator, the controller agent, the account agent, and the bank agent), (B) client agents, and (C) one mediator agent. The market mechanisms used were an unmediated one, Contract Net, and a mediated one, the sealed bid, periodic, uniform-price, double auction. Experiments showed that overhead and gain were quite similar for the two market mechanisms. Regarding scalability – a highly important factor for large distributed projects – the auction scored clearly better than Contract Net. 1 Allocation of computational resources Over the years, the computational problems around the globe have increased in size an

Automatic ontology mapping for agent communication

Agent communication languages such as ACL and KQML provide a standard for agent communication. These languages enable an agent to specify the intention and the content of a message as well as the protocol, the language, and the ontology that are used. For the protocol and the language some standards are available and should be known by the communicating agents. The ontology used in a communication depends on the subject of the communication. Since the number of subjects is almost infinite and since the concepts used for a subject can be described by different ontologies, the development of generally accepted standards will take a long time. This lack of standardization, which hampers communication and collaboration between agents, is known as the interoperability problem. To overcome the interoperability problem, agents must be able to establish a mapping between their ontologies. This paper investigates a new approach to the interoperability problem. The proposed approach uses no background knowledge and requires neither a correspondence between concepts used in the ontologies nor a correspondence between the structure of the ontologies. It only requires that some instances of the subject about which the agents try to communicate are known by both agents.