318 research outputs found

    OpenCL Actors - Adding Data Parallelism to Actor-based Programming with CAF

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    The actor model of computation has been designed for a seamless support of concurrency and distribution. However, it remains unspecific about data parallel program flows, while available processing power of modern many core hardware such as graphics processing units (GPUs) or coprocessors increases the relevance of data parallelism for general-purpose computation. In this work, we introduce OpenCL-enabled actors to the C++ Actor Framework (CAF). This offers a high level interface for accessing any OpenCL device without leaving the actor paradigm. The new type of actor is integrated into the runtime environment of CAF and gives rise to transparent message passing in distributed systems on heterogeneous hardware. Following the actor logic in CAF, OpenCL kernels can be composed while encapsulated in C++ actors, hence operate in a multi-stage fashion on data resident at the GPU. Developers are thus enabled to build complex data parallel programs from primitives without leaving the actor paradigm, nor sacrificing performance. Our evaluations on commodity GPUs, an Nvidia TESLA, and an Intel PHI reveal the expected linear scaling behavior when offloading larger workloads. For sub-second duties, the efficiency of offloading was found to largely differ between devices. Moreover, our findings indicate a negligible overhead over programming with the native OpenCL API.Comment: 28 page

    Thermoforming of planar polymer optical waveguides for integrated optics in smart packaging materials

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    The innovations in smart packaging will open up a wide range of opportunities in the future. This work describes the processing of additive manufactured and planar integrated polymer optical waveguides for use in smart packaging products. The previously published combination of flexographic and Aerosol Jet printing is complemented by thermoforming and thus creates three-dimensional integrated multimode waveguides with optical attenuation of 1.9 dB/cm ± 0.1 dB/cm @ 638 nm. These properties will be the basis to develop smart applications in packaging materials

    Ablation and functionalization of flexographic printing forms using femtosecond lasers for additively manufactured polymer-optical waveguides

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    An efficient and low-cost approach to manufacture Opto-Mechatronic Interconnect Devices will be obligatory to handle the strongly increasing amount of data. The presented approach is based on a flexographic printing process. To adjust the transferred material the printing form is functionalized by means of laser-induced structures using an ultrashort-pulsed laser. The long-term goal is to adjust the printing result through microstructures in the printing form in order to create spatially resolved material transfer. In this work, first the ablation parameters are investigated at different repetition rates using a femtosecond laser. Further, a line structure is inserted in the material transferring areas of the printing form, which is consequently widened. Its influence on the printing result is presented. © 2020 The Authors. Published by Elsevier B.V

    What is important in evaluating health care quality? An international comparison of user views

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    BACKGROUND: Quality of care from the perspective of users is increasingly used in evaluating health care performance. Going beyond satisfaction studies, quality of care from the users' perspective is conceptualised in two dimensions: the importance users attach to aspects of care and their actual experience with these aspects. It is well established that health care systems differ in performance. The question in this article is whether there are also differences in what people in different health care systems view as important aspects of health care quality. The aim is to describe and explain international differences in the importance that health care users attach to different aspects of health care. METHODS: Data were used from different studies that all used a version of the QUOTE-questionnaire that measures user views of health care quality in two dimensions: the importance that users attach to aspects of care and their actual experience. Data from 12 European countries and 5133 individuals were used. They were analysed using multi-level analysis. RESULTS: Although most of the variations in importance people attach to aspects of health care is located at the individual level, there are also differences between countries. The ranking of aspects shows similarities. 'My GP should always take me seriously' was in nearly all countries ranked first, while an item about waiting time in the GP's office was always ranked lowest. CONCLUSION: Differences between countries in how health care users value different aspects of care are difficult to explain. Further theorising should take into account that importance and performance ratings are positively related, that people compare their experiences with those of others, and that general and instrumental values might be related through the institutions of the health care system

    Prospectus, October 31, 1979

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    FROM POLIDENT TO EFFERVESCENT: DOWNTOWN TO BE VINTAGE; Week in Review: Across the globe, In the nation, Throughout the state, Around the town; Poltergeists bump at night; Elam wins state CC; Correction…; Wilson thanks Ziggy fans; Briefs: Forum discusses survey, Brazilian pianist at Monticello Nov. 4, Debate: has America failed?, Art field trip features Toulouse-Lautrec, NHB sponsors student awards, One woman is \u27nine Women\u27, EMT workshop at PC Nov. 17, Parkland presents Survival Program; Weekly Calendar; Preppy yet potent: Heads progress the hard way; Letters to the Editor: Rep. Johnson opposes veto; When weather break thieves break in; Foreigners complain again; Treaters shouldn\u27t \u27trick\u27; Amittyville: fact or fiction?; Survey handed out next week; Classifieds; Checks cashable in Nov.; College Day at PC Nov. 7; Model govt. needs plans; Earn less than $6,000? Elgible for higher grant; Parkland offers Folkore; Harmful materials to be discusses; Knee surgery ousts Short; Home no help for golfers; You\u27ve waited long enough: shape up; Soccer club wins; Freddy heading toward poverty; Fast Freddy Contesthttps://spark.parkland.edu/prospectus_1979/1006/thumbnail.jp

    Optimistic Parallelism on GPUs

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    Abstract. We present speculative parallelization techniques that can exploit parallelism in loops even in the presence of dynamic irregulari-ties that may give rise to cross-iteration dependences. The execution of a speculatively parallelized loop consists of five phases: scheduling, com-putation, misspeculation check, result committing, and misspeculation recovery. While the first two phases enable exploitation of data paral-lelism, the latter three phases represent overhead costs of using specu-lation. We perform misspeculation check on the GPU to minimize its cost. We perform result committing and misspeculation recovery on the CPU to reduce the result copying and recovery overhead. The scheduling policies are designed to reduce the misspeculation rate. Our program-ming model provides API for programmers to give hints about potential misspeculations to reduce their detection cost. Our experiments yielded speedups of 3.62x-13.76x on an nVidia Tesla C1060 hosted in an Intel(R) Xeon(R) E5540 machine.

    Systemic and Tissue Inflammation in Juvenile Dermatomyositis: From Pathogenesis to the Quest for Monitoring Tools

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    Juvenile Dermatomyositis (JDM) is a systemic immune-mediated disease of childhood, characterized by muscle weakness, and a typical skin rash. Other organ systems and tissues such as the lungs, heart, and intestines can be involved, but may be under-evaluated. The inflammatory process in JDM is characterized by an interferon signature and infiltration of immune cells such as T cells and plasmacytoid dendritic cells into the affected tissues. Vasculopathy due to loss and dysfunction of endothelial cells as a result of the inflammation is thought to underlie the symptoms in most organs and tissues. JDM is a heterogeneous disease, and several disease phenotypes, each with a varying combination of affected tissues and organs, are linked to the presence of myositis autoantibodies. These autoantibodies have therefore been extensively studied as biomarkers for the disease phenotype and its associated prognosis. Next to identifying the JDM phenotype, monitoring of disease activity and disease-inflicted damage not only in muscle and skin, but also in other organs and tissues, is an important part of clinical follow-up, as these are key determinants for the long-term outcomes of patients. Various monitoring tools are currently available, among which clinical assessment, histopathological investigation of muscle and skin biopsies, and laboratory testing of blood for specific biomarkers. These investigations also give novel insights into the underlying immunological processes that drive inflammation in JDM and suggest a strong link between the interferon signature and vasculopathy. New tools are being developed in the quest for minimally invasive, but sensitive and specific diagnostic methods that correlate well with clinical symptoms or reflect local, low-grade inflammation. In this review we will discuss the types of (extra)muscular tissue inflammation in JDM and their relation to vasculopathic changes, critically assess the available diagnostic methods including myositis autoantibodies and newly identified biomarkers, and reflect on the immunopathogenic implications of identified markers
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