283 research outputs found
Parameters for a Super-Flavor-Factory
A Super Flavor Factory, an asymmetric energy e+e- collider with a luminosity
of order 10^36 cm-2s-1, can provide a sensitive probe of new physics in the
flavor sector of the Standard Model. The success of the PEP-II and KEKB
asymmetric colliders in producing unprecedented luminosity above 10^34 cm-2s-1
has taught us about the accelerator physics of asymmetric e+e- colliders in a
new parameter regime. Furthermore, the success of the SLAC Linear Collider and
the subsequent work on the International Linear Collider allow a new
Super-Flavor collider to also incorporate linear collider techniques. This note
describes the parameters of an asymmetric Flavor-Factory collider at a
luminosity of order 10^36 cm-2s-1 at the Upsilon(4S) resonance and about 10^35
cm-2s-1 at the Tau production threshold. Such a collider would produce an
integrated luminosity of about 10,000 fb-1 (10 ab-1) in a running year (10^7
sec) at the Upsilon(4S) resonance.Comment: Flavor Physics & CP Violation Conference, Vancouver, 200
Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness.
Antibody-mediated immune responses rely on antigen recognition by the B cell antigen receptor (BCR) and the proper engagement of its intracellular signal effector proteins. Src homology (SH) 2 domain-containing leukocyte protein of 65 kDa (SLP65) is the key scaffold protein mediating BCR signaling. In resting B cells, SLP65 colocalizes with Cbl-interacting protein of 85 kDa (CIN85) in cytoplasmic granules whose formation is not fully understood. Here we show that effective B cell activation requires tripartite phase separation of SLP65, CIN85, and lipid vesicles into droplets via vesicle binding of SLP65 and promiscuous interactions between nine SH3 domains of the trimeric CIN85 and the proline-rich motifs (PRMs) of SLP65. Vesicles are clustered and the dynamical structure of SLP65 persists in the droplet phase in vitro. Our results demonstrate that phase separation driven by concerted transient interactions between scaffold proteins and vesicles is a cellular mechanism to concentrate and organize signal transducers
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Analysis of the Wakefield Effects in the PEP-II SLAC B-FACTORY
We present the history and analysis of different wake field effects throughout the operational life of the PEP-II SLAC B-factory. Although the impedance of the high and low energy rings is small, the intense high current beams generated a lot of power. The effects from these wake fields are: heating and damage of vacuum beam chamber elements like RF seals, vacuum valves , shielded bellows, BPM buttons and ceramic tiles; vacuum spikes, vacuum instabilities and high detector background; beam longitudinal and transverse instabilities. We also discuss the methods used to eliminate these effects. Results of this analysis and the PEP-II experience may be very useful in the design of new storage rings and light sources
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Changing the PEP-II Center-of-Mass Energy Down to 10 GeV and up to 11 GeV
PEP-II, the SLAC, LBNL, LLNL B-Factory was designed and optimized to run at the Upsilon 4S resonance (10.580 GeV with an 8.973 GeV e- beam and a 3.119 GeV e+ beam). The interaction region (IR) used permanent magnet dipoles to bring the beams into a head-on collision. The first focusing element for both beams was also a permanent magnet. The IR geometry, masking, beam orbits and beam pipe apertures were designed for 4S running. Even though PEP-II was optimized for the 4S, we successfully changed the center-of-mass energy (E{sub cm}) down to the Upsilon 2S resonance and completed an E{sub cm} scan from the 4S resonance up to 11.2 GeV. The luminosity throughout most of these changes remained near 1 x 10{sup 34} cm{sup -2}s{sup -1}. The E{sub cm} was changed by moving the energy of the high-energy beam (HEB). The beam energy differed by more than 20% which produced significantly different running conditions for the RF system. The energy loss per turn changed 2.5 times over this range. We describe how the beam energy was changed and discuss some of the consequences for the beam orbit in the interaction region. We also describe some of the RF issues that arose and how we solved them as the high-current HEB energy changed
Design of beam optics for the Future Circular Collider e+e- -collider rings
A beam optics scheme has been designed for the Future Circular Collider-e+e-
(FCC-ee). The main characteristics of the design are: beam energy 45 to 175
GeV, 100 km circumference with two interaction points (IPs) per ring,
horizontal crossing angle of 30 mrad at the IP and the crab-waist scheme [1]
with local chromaticity correction. The crab-waist scheme is implemented within
the local chromaticity correction system without additional sextupoles, by
reducing the strength of one of the two sextupoles for vertical chromatic
correction at each side of the IP. So-called "tapering" of the magnets is
applied, which scales all fields of the magnets according to the local beam
energy to compensate for the effect of synchrotron radiation (SR) loss along
the ring. An asymmetric layout near the interaction region reduces the critical
energy of SR photons on the incoming side of the IP to values below 100 keV,
while matching the geometry to the beam line of the FCC proton collider
(FCC-hh) [2] as closely as possible. Sufficient transverse/longitudinal dynamic
aperture (DA) has been obtained, including major dynamical effects, to assure
an adequate beam lifetime in the presence of beamstrahlung and top-up
injection. In particular, a momentum acceptance larger than +/-2% has been
obtained, which is better than the momentum acceptance of typical collider
rings by about a factor of 2. The effects of the detector solenoids including
their compensation elements are taken into account as well as synchrotron
radiation in all magnets. The optics presented in this paper is a step toward a
full conceptual design for the collider. A number of issues have been
identified for further study
The FCC-ee study: Progress and challenges
The FCC (Future Circular Collider) study represents a vision for the next
large project in high energy physics, comprising an 80-100 km tunnel that can
house a future 100 TeV hadron collider. The study also includes a high
luminosity e+e- collider operating in the centre-of-mass energy range of 90-350
GeV as a possible intermediate step, the FCC-ee. The FCC-ee aims at definitive
electro-weak precision measurements of the Z, W, H and top particles, and
search for rare phenomena. Although FCC-ee is based on known technology, the
goal performance in luminosity and energy calibration make it quite
challenging. During 2014 the study went through an exploration phase. The study
has now entered its second year and the aim is to produce a conceptual design
report during the next three to four years. We here report on progress since
the last IPAC conference.Comment: Poster presented at IPAC15,Richmond, VA, USA, May 201
SuperB: a linear high-luminosity B Factory
This paper is based on the outcome of the activity that has taken place
during the recent workshop on "SuperB in Italy" held in Frascati on November
11-12, 2005. The workshop was opened by a theoretical introduction of Marco
Ciuchini and was structured in two working groups. One focused on the machine
and the other on the detector and experimental issues.
The present status on CP is mainly based on the results achieved by BaBar and
Belle. Estabilishment of the indirect CP violation in B sector in 2001 and of
the direct CP violation in 2004 thanks to the success of PEP-II and KEKB e+e-
asymmetric B Factories operating at the center of mass energy corresponding to
the mass of the Y(4s). With the two B Factories taking data, the Unitarity
Triangle is now beginning to be overconstrained by improving the measurements
of the sides and now also of the angles alpha, and gamma. We are also in
presence of the very intriguing results about the measurements of sin(2 beta)
in the time dependent analysis of decay channels via penguin loops, where b -->
s sbar s and b --> s dbar d. Tau physics, in particular LFV search, as well as
charm and ISR physics are important parts of the scientific program of a SuperB
Factory. The physics case together with possible scenarios for the high
luminosity SuperB Factory based on the concepts of the Linear Collider and the
related experimental issues are discussed.Comment: 22 pages, 22 figures, INFN Roadmap Repor
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