165 research outputs found
Multiphoton Coincidence Spectroscopy
We extend the analysis of photon coincidence spectroscopy beyond bichromatic
excitation and two-photon coincidence detection to include multichromatic
excitation and multiphoton coincidence detection. Trichromatic excitation and
three-photon coincidence spectroscopy are studied in detail, and we identify an
observable signature of a triple resonance in an atom-cavity system.Comment: 6 page, REVTeXs, 6 Postscript figures. The abstract appeared in the
Proceedings of ACOLS9
Coordinated and interactive expression of genes of lipid metabolism and inflammation in adipose tissue and liver during metabolic overload
Optimal Quantum Trajectories for Continuous Measurement
We define an ideal optimal quantum measurement as that measurement on the apparatus for which the average algorithmic information in the measurement record is minimized. We apply the definition to a chaotic system subject to continuous (Markov) quantum nondemolition measurements. For optimized measurements the average information in the record is much closer to the von Neumann entropy than in the nonoptimized case, but increases more quickly in the chaotic region than in the regular region
Nonclassical Fields and the Nonlinear Interferometer
We demonstrate several new results for the nonlinear interferometer, which
emerge from a formalism which describes in an elegant way the output field of
the nonlinear interferometer as two-mode entangled coherent states. We clarify
the relationship between squeezing and entangled coherent states, since a weak
nonlinear evolution produces a squeezed output, while a strong nonlinear
evolution produces a two-mode, two-state entangled coherent state. In between
these two extremes exist superpositions of two-mode coherent states manifesting
varying degrees of entanglement for arbitrary values of the nonlinearity. The
cardinality of the basis set of the entangled coherent states is finite when
the ratio is rational, where is the nonlinear strength. We
also show that entangled coherent states can be produced from product coherent
states via a nonlinear medium without the need for the interferometric
configuration. This provides an important experimental simplification in the
process of creating entangled coherent states.Comment: 21 pages, 2 figure
Quantum nonlocality and applications in quantum-information processing of hybrid entangled states
The hybrid entangled states generated, e.g., in a trapped-ion or atom-cavity
system, have exactly one ebit of entanglement, but are not maximally entangled.
We demonstrate this by showing that they violate, but in general do not
maximally violate, Bell's inequality due to Clauser, Horne, Shimony and Holt.
These states are interesting in that they exhibit the entanglement between two
distinct degrees of freedom (one is discrete and another is continuous). We
then demonstrate these entangled states as a valuable resource in quantum
information processing including quantum teleportation, entanglement swapping
and quantum computation with "parity qubits". Our work establishes an
interesting link between quantum information protocols of discrete and
continuous variables.Comment: 5 pages, no figur
Back to the Future: Lessons from Knowledge Engineering Methodologies for Chatbot Design and Development
Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation
Associations of Amylin with Inflammatory Markers and Metabolic Syndrome in Apparently Healthy Chinese
BACKGROUND: Cellular and animal studies implicate multiple roles of amylin in regulating insulin action, glucose and lipid metabolisms. However, the role of amylin in obesity related metabolic disorders has not been thoroughly investigated in humans. Therefore, we aimed to evaluate the distribution of circulating amylin and its association with metabolic syndrome (MetS) and explore if this association is influenced by obesity, inflammatory markers or insulin resistance in apparently healthy Chinese. METHODS: A population-based sample of 1,011 Chinese men and women aged 35-54 years was employed to measure plasma amylin, inflammatory markers (C-reactive protein [CRP] and interleukin-6 [IL-6]), insulin, glucose and lipid profiles. MetS was defined according to the updated National Cholesterol Education Program Adult Treatment Panel III criteria for Asian-Americans. RESULTS: Plasma amylin concentrations were higher in overweight/obese participants than normal-weight counterparts (P<0.001) without sex difference. Circulating amylin was positively associated with CRP, IL-6, BMI, waist circumference, blood pressure, fasting glucose, insulin, amylin/insulin ratio, HOMA-IR, LDL cholesterol and triglycerides, while negatively associated with HDL cholesterol (all P<0.001). After multiple adjustments, the risk of MetS was significantly higher (odds ratio 3.71; 95% confidence interval: 2.53 to 5.46) comparing the highest with the lowest amylin quartile. The association remained significant even further controlling for BMI, inflammatory markers, insulin or HOMA-IR. CONCLUSIONS: Our study suggests that amylin is strongly associated with inflammatory markers and MetS. The amylin-MetS association is independent of established risk factors of MetS, including obesity, inflammatory markers and insulin resistance. The causal role of hyperamylinemia in the development of MetS needs to be confirmed prospectively
Multilocus Genotyping of Human Giardia Isolates Suggests Limited Zoonotic Transmission and Association between Assemblage B and Flatulence in Children
Giardia intestinalis is a protozoan parasite found world-wide and it is a major cause of diarrhea in humans and other mammals. The genetic variability within G. intestinalis is high with eight distinct genotypes or assemblages (A-H). Here we performed sequence-based multilocus genotyping of around 200 human Giardia isolates. We found evidence of limited zoonotic transmission of certain A subtypes and an association between flatulence and assemblage B infection in children. This shows that it is important to investigate different assemblages and sub-assemblages of G. intestinalis in human infections in order to understand the clinical significance, zoonotic potential, sequence divergence, and transmission pathways of this parasite
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