Practical trapped-ion protocols for universal qudit-based quantum computing

The notion of universal quantum computation can be generalized to multi-level qudits, which offer advantages in resource usage and algorithmic efficiencies. Trapped ions, which are pristine and well-controlled quantum systems, offer an ideal platform to develop qudit-based quantum information processing. Previous work has not fully explored the practicality of implementing trapped-ion qudits accounting for known experimental error sources. Here, we describe a universal set of protocols for state preparation, single-qudit gates, a new generalization of the M\o{}lmer-S\o{}rensen gate for two-qudit gates, and a measurement scheme which utilizes shelving to a meta-stable state. We numerically simulate known sources of error from previous trapped ion experiments, and show that there are no fundamental limitations to achieving fidelities above $99\%$ for three-level qudits encoded in $^{137}\mathrm{Ba}^+$ ions. Our methods are extensible to higher-dimensional qudits, and our measurement and single-qudit gate protocols can achieve $99\%$ fidelities for five-level qudits. We identify avenues to further decrease errors in future work. Our results suggest that three-level trapped ion qudits will be a useful technology for quantum information processing

Detained Adolescents: Mental Health Needs, Treatment Use, and Recidivism

Objective: Although approximately 60%-70% of detained adolescents meet criteria for a mental disorder, few receive treatment upon community reentry. Given that mental health treatment can potentially reduce recidivism, the study examined detained adolescents’ mental health needs and their post-detention mental health treatment and recidivism. Method: Altogether, 1574 adolescents (<18 years) completed a mental health screener at a detention center. Scores on the screener, mental health treatment utilization (60-days post-detention), and recidivism (6-months post-detention) were measured. Results: About 82.2% of adolescents earned elevated scores on the mental health screener, but only 16.4% utilized treatment and 37.2% recidivated. Logistic regression models revealed adolescents with insurance and higher Angry-Irritable scores were significantly more likely to obtain treatment, whereas males, Black adolescents, older adolescents, and adolescents endorsing a trauma history were less likely. Black adolescents, insured adolescents, and adolescents with higher Alcohol/Drug Use scores were significantly more likely to recidivate. Mental health treatment increased the likelihood of recidivism. Discussion: The prevalence of mental health needs among DAs was high, but treatment utilization was low, with notable treatment disparities across race, gender, and age. The use of mental health treatment predicted recidivism, suggesting treatment may act as a proxy measure of mental health problems. Future research should assess the impact of timely and continuous mental health services on recidivism

Immune Response Testing of Electrospun Polymers: An Important Consideration in the Evaluation of Biomaterials

Due primarily to cell sourcing issues, many in the field of tissue engineering have opted to create scaffolds that promote in situ regeneration, using the body as both the bioreactor and the cell source for the remodeling of scaffolds, resulting in the formation of native tissue. This practice raises many concerns, with the body’s immune response to such an implant often being neglected as a potential problem in preliminary design and biocompatibility testing. More importantly, what happens over time in terms of the immune responses as the biodegradable scaffold structures being utilized to promote in situ regeneration begin to degrade, forming structural fragments and degradation products? In summary, immune response evaluations are critical considerations that must be conducted when evaluating bioresorbable scaffolds. In addition, it is essential that these evaluations analyze materials for their potential dose-response and time-course effects on the various components of innate and acquired immunity

Lower Postsurgical Mortality for Individuals with Dementia with Better-Educated Hospital Workforce

Surgical patients age 65 and over with Alzheimer’s disease and related dementias (ADRD) were more likely to die within 30 days of admission and to die after a complication than those without ADRD. Having better-educated nurses in the hospital improved the likelihood of good outcomes for all surgical patients, but had a much greater effect in individuals with ADRD. Specifically, a 10% increase in the proportion of nurses with a Bachelor of Science in Nursing (BSN) degree or higher was associated with 10% lower odds of death and 10% lower odds of dying after a complication for surgical patients with ADRD