COMPARISON OF THE INFLUENCE OF THREE TYPES OF MILITARY BOOT INSOLE UPON THE FORCE AND LOADING RATES EXPERIENCED IN DROP JUMP LANDING

Eight male subjects performed drop jumps from a 0.8 m high platform onto a force plate and landing forces were sampled at 1000Hz. Six jumps were completed wearing military boots fitted with three different insoles (Saran, Poron and Sorbathane), and also when barefoot. Comparison of the last five jumps in each case showed that mean peak forces were similar (7.5 BW) for all insoles, though the forefoot impact mean (±SE) loading rate was higher for Sorbathane (754 ± 77 BWs-1) than for Saran (552 ± 58 BWs-1) or Poron (636 ± 77BWs-1). Mean peak loading rates for Poron, Saran and Sorbathane from forefoot to heel contact were similar for Saran (249 BWs-1) and Poron (254 BWs-1) and slightly higher for Sorbathane (300 BWs-1). Barefoot peak forces and both forefoot impact and peak loading rate were less than when a boot was worn with an insole

Explosivity : an unusual challenge in drug development

There remains an urgent global need for new drugs to combat diseases such as malaria, tuberculosis and cancer, as well as overcoming increasing antibiotic resistance. Chemists are moving into ‘new chemical space’ for drug design (1,2) and with this comes the possibility of traditional (and stable) ‘carbon-carbon’ bond structures being replaced by more ‘exotic’ bonding arrangements. While the implication of this on pharmaceutical stability can often be mitigated by suitable formulation and storage strategies, we came across an unusual case of chemical stability: the possibility that the drug was an explosive! By pushing drug designing into uncharted chemical space it could be argued that the possibility of finding explosive molecules of pharmaceutical interest will increase

\u3ci\u3eMedicine Meets Virtual Reality 14\u3c/i\u3e

Chapter, Real-Time Augmented Feedback Benefits Robotic Laparoscopic Training, co-authored by Nicholas Steriou, UNO faculty member. Machine intelligence will eclipse human intelligence within the next few decades - extrapolating from Moore’s Law - and our world will enjoy limitless computational power and ubiquitous data networks. Today’s iPod® devices portend an era when biology and information technology will fuse to create a human experience radically different from our own. Already, our healthcare system now appears on the verge of crisis; accelerating change is part of the problem. Each technological upgrade demands an investment of education and money, and a costly infrastructure more quickly becomes obsolete. Practitioners can be overloaded with complexity: therapeutic options, outcomes data, procedural coding, drug names etc. Furthermore, an aging global population with a growing sense of entitlement demands that each medical breakthrough be immediately available for its benefit: what appears in the morning paper is expected simultaneously in the doctor’s office. Meanwhile, a third-party payer system generates conflicting priorities for patient care and stockholder returns. The result is a healthcare system stressed by scientific promise, public expectation, economic and regulatory constraints and human limitations. Change is also proving beneficial, of course. Practitioners are empowered by better imaging methods, more precise robotic tools, greater realism in training simulators, and more powerful intelligence networks. The remarkable accomplishments of the IT industry and the Internet are trickling steadily into healthcare. The Medicine Meets Virtual Reality series can readily see the progress of the past fourteen years: more effective healthcare at a lower overall cost, driven by cheaper and better computers.https://digitalcommons.unomaha.edu/facultybooks/1236/thumbnail.jp

Bypassing the proline/thiazoline requirement of the macrocyclase PatG

Peer reviewedPublisher PD

Developing sexual competence? Exploring strategies for the provision of effective sexualities and relationships education

School-based sexualities and relationships education (SRE) offers one of the most promising means of improving young people's sexual health through developing 'sexual competence'. In the absence of evidence on whether the term holds the same meanings for young people and adults (e.g. teachers, researchers, policy-makers), the paper explores 'adult' notions of sexual competence as construed in research data and alluded to in UK Government guidance on SRE, then draws on empirical research with young people on factors that affect the contexts, motivations and outcomes of sexual encounters, and therefore have implications for sexual competence. These data from young people also challenge more traditional approaches to sexualities education in highlighting disjunctions between the content of school-based input and their reported sexual experience. The paper concludes by considering the implications of these insights for developing a shared notion of what SRE is trying to achieve and suggestions for recognition in the content and approaches to SRE.</p