1,017 research outputs found
Magnetomotive drive and detection of clamped-clamped mechanical resonators in water
We demonstrate magnetomotive drive and detection of doubly clamped string
resonators in water. A compact 1.9 T permanent magnet is used to detect the
fundamental and higher flexural modes of long resonators.
Good agreement is found between the magnetomotive measurements and optical
measurements performed on the same resonator. The magnetomotive detection
scheme can be used to simultaneously drive and detect multiple sensors or
scanning probes in viscous fluids without alignment of detector beams.Comment: 4 pages, 3 figure
Nonlinear modal interactions in clamped-clamped mechanical resonators
A theoretical and experimental investigation is presented on the intermodal
coupling between the flexural vibration modes of a single clamped-clamped beam.
Nonlinear coupling allows an arbitrary flexural mode to be used as a
self-detector for the amplitude of another mode, presenting a method to measure
the energy stored in a specific resonance mode. Experimentally observed complex
nonlinear dynamics of the coupled modes are quantitatively captured by a model
which couples the modes via the beam extension; the same mechanism is
responsible for the well-known Duffing nonlinearity in clamped-clamped beams.Comment: 5 pages, 3 figure
Interactions between directly and parametrically driven vibration modes in a micromechanical resonator
The interactions between parametrically and directly driven vibration modes
of a clamped-clamped beam resonator are studied. An integrated piezoelectric
transducer is used for direct and parametric excitation. First, the parametric
amplification and oscillation of a single mode are analyzed by the power and
phase dependence below and above the threshold for parametric oscillation.
Then, the motion of a parametrically driven mode is detected by the induced
change in resonance frequency in another mode of the same resonator. The
resonance frequency shift is the result of the nonlinear coupling between the
modes by the displacement-induced tension in the beam. These nonlinear modal
interactions result in the quadratic relation between the resonance frequency
of one mode and the amplitude of another mode. The amplitude of a
parametrically oscillating mode depends on the square root of the pump
frequency. Combining these dependencies yields a linear relation between the
resonance frequency of the directly driven mode and the frequency of the
parametrically oscillating mode.Comment: 5 pages, 4 figure
Q-factor control of a microcantilever by mechanical sideband excitation
We demonstrate the coupling between the fundamental and second flexural mode
of a microcantilever. A mechanical analogue of cavity-optomechanics is then
employed, where the mechanical cavity is formed by the second vibrational mode
of the same cantilever, coupled to the fundamental mode via the geometric
nonlinearity. By exciting the cantilever at the sum and difference frequencies
between fundamental and second flexural mode, the motion of the fundamental
mode of the cantilever is amplified and damped. This concept makes it possible
to enhance or suppress the Q-factor over a wide range.Comment: 9 pages, 3 figure
[18F]Sodium Fluoride PET has the potential to identify active formation of calcinosis cutis in limited cutaneous systemic sclerosis
OBJECTIVES: Calcinosis cutis affects 20-40% of patients with systemic sclerosis (SSc). When calcinosis cutis becomes clinically apparent, it is irreversible in most cases. Detection of active calcification formation might allow early disease-modifying interventions. We assessed the feasibility of visualizing active calcifications using [18F]Sodium Fluoride ([18F]NaF) PET/low-dose CT (LDCT) in SSc patients with calcinosis cutis. METHODS: In this cross-sectional, observational pilot study patients underwent a whole body [18F]NaF PET/LDCT. All patients met the 2013 ACR/EULAR SSc criteria and had clinically detectable calcinosis cutis. (Sub)cutaneous calcifications were described by three investigators. RESULTS: Nine female patients were included (median age 59.0 years [IQR 51.5-70.5]). [18F]NaF uptake was mostly visible in the fingers (n=7) and knees (n=5). [18F]NaF PET showed calcifications in the fingers of 3 patients where calcifications were undetected on LDCT and in the clinic. Ninety-seven percent of [18F]NaF positive lesions was visible on LDCT. Of all lesions visible on LDCT, 70% was also visible on [18F]NaF PET. CONCLUSION: Imaging of active calcifications in SSc is feasible using [18F]NaF PET/LDCT. Seventy percent of calcifications on LDCT were [18F]NaF PET positive. Although these findings require replication, [18F]NaF PET/LDCT may detect active calcification formation, being potentially suitable for early disease-modifying interventions
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