1,059 research outputs found

    Arm Lymphedema as a Consequence of Breast Cancer Therapy

    Get PDF

    Characterization of site-specific GPS errors using a short-baseline network of braced monuments at Yucca Mountain, southern Nevada

    Get PDF
    We use a short-baseline network of braced monuments to investigate site-specific GPS effects. The network has baseline lengths of ∼10, 100, and 1000 m. Baseline time series have root mean square (RMS) residuals, about a model for the seasonal cycle, of 0.05–0.24 mm for the horizontal components and 0.20–0.72 mm for the radial. Seasonal cycles occur, with amplitudes of 0.04–0.60 mm, even for the horizontal components and even for the shortest baselines. For many time series these lag seasonal cycles in local temperature measurements by 23–43 days. This could suggest that they are related to bedrock thermal expansion. Both shorter-period signals and seasonal cycles for shorter baselines to REP2, the one short-braced monument in our network, are correlated with temperature, with no lag time. Differences between REP2 and the other stations, which are deep-braced, should reflect processes occurring in the upper few meters of the ground. These correlations may be related to thermal expansion of these upper ground layers, and/or thermal expansion of the monuments themselves. Even over these short distances we see a systematic increase in RMS values with increasing baseline length. This, and the low RMS levels, suggests that site-specific effects are unlikely to be the limiting factor in the use of similar GPS sites for geophysical investigations

    Restricted single isocenter for multiple targets dynamic conformal arc (RSIMT DCA) technique for brain stereotactic radiosurgery (SRS) planning.

    Get PDF
    In stereotactic radiosurgery (SRS), the multiple isocenters for multiple targets dynamic conformal arc (MIMT DCA) technique is traditionally used to treat multiple brain metastases, with one isocenter for each target. The single isocenter for multiple targets (SIMT) technique has recently been adopted to reduce the treatment time at the cost of plan quality. The objective of this study was to develop a restricted single isocenter for multiple targets DCA (RSIMT DCA) technique that can significantly reduce the treatment time but still maintain similar plan quality as the MIMT DCA technique.Treating multiple brain metastases with a single isocenter poses a challenge to SRS planning using DCA beams that are intrinsically 3D and do not modulate the beam intensity to spare the normal tissue between targets. To address this obstacle, we have developed a RSIMT DCA technique and used it to treat SRS patients with multiple brain metastases since February 2015. This planning approach is similar to the SIMT technique except that the number of targets for each isocenter is restricted and the distance between the isocenter and target is limited. In this technique, the targets are first split into batches so that all targets in a batch are within a chosen distance (e.g., 7 cm) of each other. All targets in a batch are combined into one target and the geometric center of the combined target is the isocenter for the group of DCA beams associated with that batch. Each DCA group typically consists of 3-4 DCA beams to irradiate 1-3 targets. For each DCA beam, the collimator angle is adjusted to minimize the exposure of normal tissue between targets. The dose of each treatment group is normalized so that the maximal point dose to the combined target is 125% of the prescription dose, which is equivalent to normalize the prescription dose to 80% isodose line. If the maximal point dose of a target is 95% and V19Gy=100%) was achieved for all plans using either technique. Most PTVs have a maximal point dose between 24.9 and 25.1 Gy, with 2 PTVs between 24.5 and 24.9 Gy. Overall, the plan quality was slightly better for the MIMT DCA technique and the normalized difference was statistically significantly larger than 0 for all investigated dose quality indexes. The normalized difference of body mean dose and conformity index (CI) between the RSIMT and MIMT techniques was respectively 4.2% (p=0.002) and 9.4% (p=0.001), indicating similar plan quality globally and in the high dose area. The difference was more pronounced for the mid-to-low dose spillage with the ratios of V12Gy and V10Gy/VPTV being 13.9% (p=3.8×10-6) and 14.9% (p=1.3×10-5), respectively. The treatment time was reduced by 30%-50% with the RSIMT DCA technique.The RSIMT DCA technique can produce satisfactory SRS plans for treating multiple targets and can significantly reduce the treatment time

    Assessment of GPS velocity accuracy for the Basin and Range Geodetic Network (BARGEN)

    Get PDF
    We assess the accuracy of horizontal velocity estimates from the Basin and Range Geodetic Network (BARGEN), a continuous GPS network that has been in operation since 1996. To make this quantitative assessment, we use a procedure that we term the “whole-error” method. In this method, the measure of the velocity errors is the root-mean-square (RMS) residual velocity relative to a simple geophysical model. This method produces a conservative estimate of the uncertainties, since errors in the geophysical models also contribute to the RMS residual. Using estimates from two different BARGEN subnetworks, the Northern Basin and Range and the Yucca Mountain Cluster, we determine velocity uncertainties of 0.1–0.2 mm yr^(−1). Since BARGEN covers a significant fraction of area of the proposed Plate Boundary Observatory component of EarthScope, our results indicate a good ability of this project to determine highly accurate long-term horizontal crustal velocities and deformation rates in this region

    Thermochronometry across the Austroalpine-Pennine boundary, Central Alps, Switzerland: Orogen-perpendicular normal fault slip on a major ‘overthrust’ and its implications for orogenesis

    Get PDF
    Fifty-one new and 309 published thermochronometric ages (nine systems with closure temperatures ranging from ~450 to 70°C) from the Graubünden region of the Central Alps demonstrate that a pronounced thermal mismatch between the Austroalpine allochthon (Alpine “orogenic lid”) and the Pennine zone persisted until at least 29 Ma and, allowably, until circa 18 Ma. The observed mismatch supports previous suggestions that the famous “overthrust” between the Austroalpine allochthon and the Pennine zone, historically regarded as primarily an Eocene top-north thrust fault, is in fact primarily an Oligocene-Miocene normal fault that has a minimum of 60 km of displacement with top-south or top-southeast sense of shear. Two hallmarks of Alpine geology, deposition of the foredeep Molasse and emplacement of the Helvetic nappes, appear to be coeval, peripheral manifestations of crustal thickening via the interposition of the Pennine zone as a northward intruding wedge between the Austroalpine “lid” and the European cratonic margin, with the Helvetic system (European margin) acting as the “floor” of the wedge. We presume the Penninic wedge is driven by the buoyant rise of subducted crust no longer able to remain attached to the descending slab. If so, emplacement of the Pennine wedge could have occurred mainly after Adria was juxtaposed against cratonic Europe
    • …
    corecore