34,520 research outputs found

    Peter Walsh, double bass, February 17, 2018

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    This is the concert program of the Peter Walsh, double bass performance on Saturday, February 17, 2018 at 4:30 p.m., at the Marshall Room, 855 Commonwealth Avenue. Works performed were Arpeggione Sonata by Franz Schubert, S. Biagio 9 Agnosto ore 1207 by Hans Werner Henze, and String Quartet No. 2 by Anton Arensky. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund

    FGF-2 Induces Neuronal Death through Upregulation of System xc-

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    The cystine/glutamate antiporter (system xc-) transports cystine into cell in exchange for glutamate. Fibroblast growth factor-2 (FGF-2) upregulates system xc- selectively on astrocytes, which leads to increased cystine uptake, the substrate for glutathione production, and increased glutamate release. While increased intracellular glutathione can limit oxidative stress, the increased glutamate release can potentially lead to excitotoxicity to neurons. To test this hypothesis, mixed neuronal and glial cortical cultures were treated with FGF-2. Treatment with FGF-2 for 48 h caused a significant neuronal death in these cultures. Cell death was not observed in neuronal-enriched cultures, or astrocyte-enriched cultures, suggesting the toxicity was the result of neuron-glia interaction. Blocking system xc- eliminated the neuronal death as did the AMPA/kainate receptor antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione (NBQX), but not the NMDA receptor antagonist memantine. When cultures were exposed directly to glutamate, both NBQX and memantine blocked the neuronal toxicity. The mechanism of this altered profile of glutamate receptor mediated toxicity by FGF-2 is unclear. The selective calcium permeable AMPA receptor antagonist 1-naphthyl acetyl spermine (NASPM) failed to offer protection. The most likely explanation for the results is that 48 h FGF-2 treatment induces AMPA/kainate receptor toxicity through increased system xc- function resulting in increased release of glutamate. At the same time, FGF-2 alters the sensitivity of the neurons to glutamate toxicity in a manner that promotes selective AMPA/kainate receptor mediated toxicity

    Crying for Repression: Populist and Democratic Biopolitics in Times of COVID-19

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    We live in very Foucauldian times, as the many think-pieces published on biopolitics and COVID-19 show. Yet what is remarkable—biopolitically—about the current situation has gone largely unnoticed: We are witnessing a new form of biopolitics today that could be termed populist biopolitics. Awareness of this populist biopolitics helps illuminate what is needed today: democratic biopolitics

    Incompatibility of different customary kaon phase convention

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    The conventions that Wu and Yang assumed for the kaon phases in the context of CPCP symmetrical two-pion decay channels fix the relative kaon phase. This fact, apparently not emphasized sufficiently in the past, has recently been overlooked by Hayakawa and Sanda. In particular, Wu and Yang fix the relative phase to a different value than the one resulting from the convention CPK0=K0CP|K^{0}\rangle = |\overline{K^{0}}\rangle. The difference between the two values is made up of possible contributions from CPTCPT- and direct CPCP-violations during the decay of a kaon into a two-pion state of isospin zero.Comment: 5 pages, LaTe

    Ein Liederabend, December 3, 1987

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    This is the concert program of the Ein Liederabend performance on Thursday, December 3, 1987 at 8:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Come again, sweet love doth now invite by John Dowland, Flow my tears by J. Dowland, What if I never speed by J. Dowland, Le secret by Gabriel Fauré, Out of the Morning by Vincent Persichetti, Morgenlied by Franz Schubert, Alma del core by Antonio Caldara, Cabin by Paul Bowles, I'll sail upon the Dog-Star by Henry Purcell, Cara, cara e dolce by Domenico Scarlatti, Der Winterabend by F. Schubert, Chanson triste by Henri Duparc, Un moto di gioia by Wolfgang Amadeus Mozart, Schneeglöckchen by Robert Schumann, Nell by G. Fauré, Voglio amor by D. Scarlatti, Du moment qu'on aime by André Grétry, El Vito by Fernando Obradors, So wahr die Sonne scheinet by R. Schumann, Pleurs d'Or by G. Fauré, and Dialogue of a Kiss by Henry Lawes. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund

    Paul Speck

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    Capital Budgeting Techniques

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