Copper-Catalyzed Radical Difluoroalkylation and Redox Annulation of Nitroalkynes for the Construction of C2-Tetrasubstituted Indolin‑3-ones

An efficient and convenient method with wide applicability for the synthesis of C2-tetrasubstituted indolin-3-ones via copper-catalyzed redox cycloisomerization of nonprefunctionalized nitroalkynes has been developed. This protocol features simple operation, readily available starting materials, good functional group tolerance, broad scope, and diboron as the reductant

Copper/Iron-Catalyzed Aerobic Oxyphosphorylation of Terminal Alkynes Leading to β‑Ketophosphonates

A copper/iron-catalyzed oxyphosphorylation of alkynes with H-phosphonates through a radical process was developed. The present protocol provides an attractive approach to β-ketophosphonates in moderate to good yields, with the advantages of readily available substrate, high functional group tolerance and operation simplicity