Unlocking the flexibility of combined heat and power for frequency response by coordinative control with batteries

Owners of combined heat and power (CHP), e.g., industrial manufacturers, are motivated to provide frequency response to power grids due to clear financial benefits. Yet, the slow response speed of CHP limits its capability in providing such services. Moreover, frequent adjustments would cause a faster lifetime reduction of CHP and rapid pressure fluctuation in the gas network. To further unlock the flexibility of CHP, this paper integrates a battery unit with CHP via a power electronic interface. A filter-based coordinative controller is designed for smoothing short-term fluctuations in CHP outputs. Based on the filter parameters and frequency response requirements, the minimum required capacity of the battery is identified. The results show that the proposed system enhances the capability of CHP for frequency response and mitigates the associated adverse effects on the gas network. The required capacity of the battery is economically feasible considering the benefit it brings to the CHP

State-of-the-art analysis and perspectives for peer-to-peer energy trading

As a promising solution to address the “energy trilemma” confronting human society, peer-to-peer (P2P) energy trading has emerged and rapidly developed in recent years. When carrying out P2P energy trading, customers with distributed energy resources (DERs) are able to directly trade and share energy with each other. This paper summarizes and analyzes the global development of P2P energy trading based on a comprehensive review of related academic papers, research projects, and industrial practice. Key aspects in P2P energy trading are identified and discussed, including market design, trading platforms, physical infrastructure and information and communication technology (ICT) infrastructure, social science perspectives, and policy. For each key aspect, existing research and practice are critically reviewed and insights for future development are presented. Comprehensive concluding remarks are provided at the end, summarizing the major findings and perspectives of this paper. P2P energy trading is a growing field with great potential and opportunities for both academia and industry across the world

Preparation, structural and magnetic characterization of trinuclear and one-dimensional cyanide-bridged Co(III)-Cu(II) complexes

341-345By employing two trans-dicyanocobolt(III) building blocks K[Co(bpb)(CN)2] (bpb2- = 1,2-bis(pyridine-2-carboxamido)benzenate), K[Co(bpmb)(CN)2] (bpmb2- = 1,2-bis(pyridine-2-carboxamido)-4-methyl-benzenate) and one 14-membered macrocycle Cu(II) compound as assembling segment, two cyanide-bridged CoIII-CuII complexes {{[Cu(cyclam)][Co(bpb)(CN)2]}ClO4}n·nCH3OH·nH2O (1) and {[Cu(cyclam)][Co(bpmb)(CN)2]2}·4H2O (2) (cyclam = 1,4,8,11-tetraazacyclotetradecane) have been successfully prepared and characterized by elemental analysis, IR spectroscopy and X-ray structure determination. Single X-ray diffraction analysis shows that complex 1 can be structurally characterized as one-dimensional cationic single chain consisting of alternating units of [Cu(cyclam)]2+ and [Co(bpb)(CN)2]- with free ClO4- as balanced anion, while complex 2 presents cyanide-bridged neutral trinuclear bimetallic structure containing Co2Cu core, giving clear information that the substitute group on the cyanide precursor has obvious influence on the structure type of the target compound. Investigation over magnetic properties of complex 1 reveals the weak antiferromagnetic coupling between the neighboring Cu(II) ions through the diamagnetic cyanide building block

Synthesis and Biological Evaluation of Ezetimibe Analogs as Possible Cholesterol Absorption Inhibitors

In order to investigate the SAR of Ezetimibe analogs for cholesterol absorption inhibitions, amide group and electron-deficient pyridine ring were introduced to the C-(3) carbon chain of Ezetimibe. Eight new derivatives of the 2-azetidinone cholesterol absorption inhibitors have been synthesized, and all of them were enantiomerically pure. All the new compounds were evaluated for their activity to inhibit cholesterol absorption in hamsters, and most of them showed comparable effects in lowering the levels of total cholesterol in the serum

G protein–coupled estrogen receptor: a promising therapeutic target for aldosterone-induced hypertension

Aldosterone is one of the most essential hormones synthesized by the adrenal gland because it regulates water and electrolyte balance. G protein–coupled estrogen receptor (GPER) is a newly discovered aldosterone receptor, which is proposed to mediate the non-genomic pathways of aldosterone while the hormone simultaneously interacts with mineralocorticoid receptor. In contrast to its cardio-protective role in postmenopausal women via its interaction with estrogen, GPER seems to trigger vasoconstriction effects and can further induce water and sodium retention in the presence of aldosterone, indicating two entirely different binding sites and effects for estrogen and aldosterone. Accumulating evidence also points to a role of aldosterone in mediating hypertension and its risk factors via the interaction with GPER. Therefore, with this review, we aimed to summarize the research on these interactions to help (1) elucidate the role of GPER activated by aldosterone in the blood vessels, heart, and kidney; (2) compare the non-genomic actions between aldosterone and estrogen mediated by GPER; and (3) address the potential of GPER as a new promising therapeutic target for aldosterone-induced hypertension