17 research outputs found
Atrial natriuretic factor attenuates prostaglandin E<sub>2</sub>-stimulated plasma renin activity in humans
No full textThe effect of atrial natriuretic factor (ANF) 99-126 3 or 10 pmol/kg/min on increase in plasma renin activity (PRA) stimulated by a 30-min infusion of prostaglandin E2 (PGE2) 80 ng/kg/min was studied in healthy salt-replete male volunteers. PGE2 increased PRA to -230% of basal levels (p < 0.001). Concomitant infusion of ANF 3 pmol/kg/min significantly attenuated this rise in PRA to -130% of baseline values (p = 0.02, n = 10). A quantitatively similar effect was observed with ANF 10 pmol/kg/min (n = 5). We suggest, in light of previous findings, that this inhibitory effect of ANF probably represents a nonspecific action rather than a specific effect of ANF on PGE2-mediated increases in PRA
Atrial natriuretic factor attenuates prostaglandin E2-stimulated plasma renin activity in humans
No full textThe effect of atrial natriuretic factor (ANF) 99-126 3 or 10 pmol/kg/min on increase in plasma renin activity (PRA) stimulated by a 30-min infusion of prostaglandin E2 (PGE2) 80 ng/kg/min was studied in healthy salt-replete male volunteers. PGE2 increased PRA to -230% of basal levels (p < 0.001). Concomitant infusion of ANF 3 pmol/kg/min significantly attenuated this rise in PRA to -130% of baseline values (p = 0.02, n = 10). A quantitatively similar effect was observed with ANF 10 pmol/kg/min (n = 5). We suggest, in light of previous findings, that this inhibitory effect of ANF probably represents a nonspecific action rather than a specific effect of ANF on PGE2-mediated increases in PRA
Atrial Natriuretic Factor Attenuates Prostaglandin E2-Stimulated Plasma Renin Activity in Humans
No full text
Effect of angiotensin-converting enzyme inhibition on plasma brain natriuretic peptide levels in patients with heart failure
No full textClearance of brain natriuretic peptide in patients with chronic heart failure:indirect evidence for a neutral endopeptidase mechanism but against an atrial natriuretic peptide clearance receptor mechanism
No full textCyclosporin-induced renal vasoconstriction is augmented by frusemide and by angiotensin II in humans
No full textEvaluation of the buccal componet of systemic absorption with inhaled fluticasone propionate
No full textEvidence in humans for a postsynaptic interaction between noradrenaline and angiotensin II with regard to systolic but not diastolic blood pressure
No full textBrain Natriuretic Peptide: Effect on Left Ventricular Filling Patterns in Healthy Subjects
No full text
