MOESM2 of Two ways to improve myoelectric control for a transhumeral amputee after targeted muscle reinnervation: a case study

Additional file 2: Video. The video demonstrates the subject performing two tasks: moving the ball onto the shelf and pouring water from one glass to another. (FLV 8910 kb

Additional file 1 of Two ways to improve myoelectric control for a transhumeral amputee after targeted muscle reinnervation: a case study

ARAT scores. Scores of all the tasks conducted by the subject in the experiment are given in the score sheet. The tasks were selected from ARAT. (PDF 67 kb

Diterpenoids with Diverse Skeletons from the Roots of <i>Euphorbia micractina</i>

Twelve new minor diterpenoids, possessing 5/6/8 (<b>1</b> and <b>2</b>), 5/6/7/3 (<b>3</b>–<b>9</b>), and 5/6/6/4 (<b>10</b>–<b>12</b>) fused-ring skeletons, as determined by spectroscopic analysis, were isolated from an ethanol extract of the roots of <i>Euphorbia micractina</i>, together with 25 known compounds. The structures of the diterpene skeletons are rare and have been found only in compounds isolated from <i>Euphorbia micractina</i> and <i>Euphorbia villosa</i>. On the basis of the octant rule for cyclohexanones, the absolute configurations of <b>1</b>–<b>12</b>, as well as of the known euphactins A–D and euphoractins A–D (<b>13</b>–<b>15</b>), could be assigned by circular dichroism spectroscopy. In addition, the co-occurring jolkinol B (<b>16</b>) was chemically transformed to euphoractin E (<b>17</b>), supporting the absolute configuration assignment and the biogenetic relationship between the different types of diterpenes. Compound <b>9</b> showed activity against HIV-1 replication in vitro, with an IC₅₀ value of 8.8 ± 0.6 μM

A Minor Diterpenoid with a New 6/5/7/3 Fused-Ring Skeleton from <i>Euphorbia micractina</i>

A novel diterpenoid with an unprecedented 6/5/7/3 fused-ring skeleton, euphorbactin (<b>1</b>), was isolated from an ethanol extract of the roots of <i>Euphorbia micractina.</i> The structure was determined by extensive spectroscopic studies, especially by 2D NMR and CD data analysis. A proposed biosynthetic pathway and preliminary investigations of the biological activity of compound <b>1</b> are also discussed