HRCT of patient No.-glass pattern with air trapping and bronchial thickening.

<p>HRCT of patient No.-glass pattern with air trapping and bronchial thickening.</p

Comparative Study of Structures and Luminescent Properties of Three Ag(I) Complexes Utilizing an Achiral Bipyridyl‑<i>N</i> or Its Axially Chiral <i>N</i>‑Oxide Analogue

An achiral 2,2′-bipyridyl-3,3′-dicarboxylate (H₂L_N) can be oxidized to a <i>C</i>₂ axially chiral <i>N</i>-oxide analogy (<i>R</i>,<i>S</i>)-2,2′-bipyridyl-3,3′-dicarboxylate-1,1′-dioxide ((<i>R</i>,<i>S</i>)-H₂L_NO), converting normal bipyridyl-<i>N</i> to a charge-separated <i>N</i>-oxide group. The achiral H₂L_N connects the Ag­(I) ions into a 4-connected mesomeric 3D network [Ag₄(L_N)₂·(H₂O)]·3H₂O (<b>1</b>). However, as expected, with the introduction of <i>N</i>-oxide groups, {Ag₄­[(<i>R</i>,<i>S</i>)-L_NO]₂·2­(H₂O)}·H₂O (<b>2</b>) and {Ag₂­[(<i>R</i>,<i>S</i>)-L_NO]}·H₂O (<b>3</b>) contain right- and left-handedness homochiral layers. Such opposite handedness layers are linked together to give a racemic compound in <b>2</b> but <i>meso</i> double-layers in <b>3</b>. Notably, both ligands in <b>1</b>–<b>3</b> support argentophilic interactions. Moreover, a luminescent comparison of <b>1</b>–<b>3</b>, pyridyl-<i>N</i>, and its functional <i>N</i>-oxide ligands is also investigated in detail

Pulmonary function results in infants and young children.

<p>Pulmonary function results in infants and young children.</p

Disease severity evaluation method.

<p>Patient's disease severity was defined as none (summed score  = 0), mild (summed score ranged from 1 to 3), moderate (summed score ranged from 4 to 7), and severe (summed score ranged from 8 to 12).</p

Clinical characteristics and imaging results of patients (n = 25).

<p>All patients had persistent cough and wheezing, so these manifestations were not listed in the symptoms column. All patients showed mosaic pattern and air trapping by HRCT, so these imaging findings were not listed in the HRCT column. BWT =  bronchial wall thickening; Be =  Bronchiectasis</p

Fiberoptic bronchoscopy of the same patient shown in Figure 1.

<p>Complete obstructions were observed in the subsegmental anterior basal bronchus of the left lower lobe (A) and in the subsegmental lateral bronchus of the right middle lobe (B).</p

Three patterns of V/Q scan (A. mismatched ventilation; B. mismatched perfusion; C. matched ventilation-perfusion) in post-infectious BO children (patient No. 4, patient No. 21 and patient No. 12), displayed in 8 views.

<p>POS =  posterior, RPO =  right posterior oblique, RL =  right lateral, RAO =  right anterior oblique, ANT =  anterior, LAO =  left anterior oblique, LL =  left lateral, LPO =  left posterior oblique.</p

Comparative Study on Temperature-Dependent CO₂ Sorption Behaviors of Two Isostructural <i>N</i>‑Oxide-Functionalized 3D Dynamic Microporous MOFs

By functionalization of the achiral carboxylate-based pyridine-<i>N</i> ligand 2,2′-bipyridine-3,3′-dicarboxylate (H₂bpda) with <i>N</i>-oxide groups, the axially chiral ligand 2,2′-bipyridine-3,3′-dicarboxylate 1,1′-dioxide (H₂bpdado) has been obtained. On the basis of H₂bpdado and auxiliary N-donor ligands, two isostructural 3D dynamic porous Cu­(II) metal–organic frameworks (MOFs), {[Cu_0.5(bpdado)_0.5(L)_0.5]·3H₂O}_<i>n</i> (L <b>=</b> 1,2-bis­(4-pyridyl)­ethane (bpa), <i>trans</i>-1,2-bis­(4-pyridyl)­ethene (bpe) for <b>1</b> and <b>2</b>, respectively), have been synthesized, which contain <i>N</i>-oxide “open donor sites” (ODSs) and carboxyl sites on the pore surfaces. The modification of pyridine-<i>N</i> into the <i>N</i>-oxide group not only transforms the nonporous structure into a porous framework but also endows the <i>N</i>-oxide group with unique charge-separated plus electron-rich character, which may provide an enhanced affinity toward CO₂ molecules. Interestingly, both <b>1</b> and <b>2</b> present reversible structural transformation upon dehydration and rehydration. The adsorption properties of <b>1</b> and <b>2</b> have been investigated by N₂, H₂, CH₄, and CO₂ gases, and they reveal evident adsorption for CO₂ and CH₄. Both MOFs have high CO₂ uptake, CO₂ sorption affinity, and sorption selectivities of CO₂ over CH₄ and N₂. Remarkably, <b>1′</b> and <b>2′</b> exhibit intriguingly comparable temperature-dependent CO₂ sorption behaviors that can probably be attributed to the difference in bpa and bpe. First, at 195 K, <b>1′</b> and <b>2′</b> exhibit stepwise adsorption and hysteretic desorption behavior for CO₂, but in the second step, the isotherms of <b>2′</b> display a starting pressure greater than that of <b>1′</b>. Then, at 298 K, their CO₂ isotherms all show nonclassical type I adsorption, while peculiarly, at 273 K, the CO₂ isotherm of <b>1′</b> still exhibits uncommon stepwise adsorption but that of <b>2′</b> does not. Thus, these temperature-dependent CO₂ sorption behaviors indicate that there exist different threshold temperatures and pressures of channel expansion for <b>1′</b> and <b>2′</b>